Journal of Flow Chemistry
Công bố khoa học tiêu biểu
* Dữ liệu chỉ mang tính chất tham khảo
Sắp xếp:
Continuous synthesis of tetraethyl thiuram disulfide with CO2 as acid agent in a gas-liquid microdispersion system
Journal of Flow Chemistry - Tập 9 - Trang 211-220 - 2019
Herein, a continuous synthetic method of tetraethyl thiuram disulfide (TETD)
with CO2 as a weak acid reagent in a gas-liquid microdispersion reaction system
has been described. A microdispersion reaction system comprising two
microreactors for CO2 absorption and diethyldithiocarbamate acid subsequent
oxidation reaction was developed. In the first step, the main products of
absorption and oxidation...
Generation and Reactions of Vinyllithiums Using Flow Microreactor Systems
Journal of Flow Chemistry - Tập 2 - Trang 70-72 - 2012
Vinyllithiums were effectively generated by bromine-lithium exchange reaction of
vinyl bromides with one eq of s-BuLi in a flow microreactor system at 0 °C or 20
°C, although two eq of t-BuLi and much lower temperatures are required for a
conventional macro batch reaction. Subsequent reactions with various
electrophiles in the flow microreactor system gave the corresponding vinyl
compounds in good...
Flow Synthesis of Symmetrical Di- and Trisulfides Using Phase-Transfer Catalysis
Journal of Flow Chemistry - Tập 3 - Trang 118-121 - 2013
Using mild conditions and short reaction times, symmetrical disulfides have been
synthesized in flow chemistry using phase transfer catalysts to facilitate the
substitution of organohalides with disodium disulfide. Also, the synthesis of
symmetrical trisulfides was possible using this procedure with an additional
equivalent of sulfur.
A device for continuous and flexible adjustment of liquid-liquid slug size in micro-channels
Journal of Flow Chemistry - Tập 10 - Trang 409-422 - 2020
In liquid-liquid segmented flow slug size determines the interfacial area as
well as the intensity of Taylor vortices and is thus an important operational
parameter, decisive for mass transfer performance of biphasic micro-reactors and
-extractors. Resulting slug sizes conventionally depend on material properties,
flow and geometric parameters of the mixing point of the liquids. To evade
tedious m...
Photo-Induced Copper-Mediated Acrylate Polymerization in Continuous-Flow Reactors
Journal of Flow Chemistry - Tập 6 - Trang 260-267 - 2016
The synthetic scope of photo-induced copper-mediated polymerization (photoCMP)
in continuous-flow reactors is further explored. A series of monomers, namely,
methyl (MA), ethyl (EA), n-butyl (nBA), 2-hydroxyethyl (HEA), and di(ethylene
glycol) ethyl ether (DEGA) acrylate are investigated, all showing high
livingness (dispersity in the range of 1.1 and linear first order kinetics) in
the polymeriza...
Design and scale-up of continuous di-nitration reaction using pinched tube flow reactor
Journal of Flow Chemistry - Tập 11 - Trang 611-624 - 2021
Scale-up of the di-nitration reaction for synthesis of selective herbicide
pendimethalin using only nitric acid in continuous flow is presented in this
work. This work showcases an approach for smooth scale-up for an herbicide for a
production capacity of 50 kg/day using a pinched tube reactor. The approach
begins with the batch experiments followed by flow synthesis using a
1/8-inchSS316 helical ...
Synthesis of a Key Intermediate towards the Preparation of Efavirenz Using n-Butyllithium
Journal of Flow Chemistry - Tập 7 - Trang 37-40 - 2017
A key reaction in one of the routes to efavirenz, an essential drug used in the
treatment of acquired immunodeficiency syndrome (AIDS), is the ortho-lithiation
reaction of N-Boc-4-chloroaniline. For the first time, we demonstrate that the
reaction may be conducted using n-BuLi and show that the reaction may be
performed in a flow reactor with a significantly higher yield (70%) compared to
batch (2...
#Chemistry/Food Science #general #Green Chemistry #Organic Chemistry #Inorganic Chemistry #Nanochemistry #Industrial Chemistry/Chemical Engineering
Enantioselective catalytic Strecker reaction on cyclic (Z)-aldimines in flow: reaction optimization and sustainability aspects
Journal of Flow Chemistry - - Trang 1-14 - 2023
Catalytic enantioselective Strecker reactions on an achiral substrate using
sub-stoichiometric amounts of a chiral catalyst represent an evolving key
strategy for the effective synthesis of α-amino nitriles. We herein disclosed
the set-up of a flow-based methodology for enantioselective Strecker, employing
ethyl cyanoformate as a relatively safe cyanide source, a cinchona-based
catalyst, and metha...
Highlights from the Flow Chemistry Literature 2015 (Part 4)
Journal of Flow Chemistry - Tập 6 - Trang 62-66 - 2016
In this Section of the journal, the literature on continuous flow synthesis
(primarily organic synthesis and functional materials) from the period of
October–December 2015 is presented. All the publications are listed ordered by
journal name, with a Review article appearing at the end. In this quarter the
number of papers on flow synthesis of nanomaterials is relatively higher than in
the previous...
Telescoped continuous flow synthesis of phenyl acrylamide
Journal of Flow Chemistry - - 2020
Functional acrylamides are valuable intermediates for organic synthesis and
building blocks in many industrial areas, like polymer synthesis, fine chemicals
and pharmaceutics. The conventional batch reaction copes with some safety
issues, due to the intrinsic reactivity and careful handling of the reagents.
Moreover, the hazardous solvents used and the energy consumed have an enormous
environmenta...
Tổng số: 374
- 1
- 2
- 3
- 4
- 5
- 6
- 10