Journal of Diabetes & Metabolic Disorders

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Insulin resistance in hypothyroid patients under Levothyroxine therapy: a comparison between those with and without thyroid autoimmunity
Journal of Diabetes & Metabolic Disorders - Tập 13 - Trang 1-7 - 2014
Tina Mazaheri, Faranak Sharifi, Koorosh Kamali
A chronic inflammation resulting from an imbalance between pro-inflammatory and anti-inflammatory cytokines in Hashimoto’s thyroiditis (HT) might be responsible for IR in hypothyroidism. This study was performed to investigate a probable association between autoimmune background of hypothyroidism and IR. In this clinical study, 63 subjects with Hashimoto’s thyroiditis and 49 subjects with post-abl...... hiện toàn bộ
Beneficial effects of 1,3–1,6 β-glucans produced by Aureobasidium pullulans on non-esterified fatty acid levels in diabetic KKAy mice and their potential implications in metabolic dysregulation
Journal of Diabetes & Metabolic Disorders - Tập 22 - Trang 487-494 - 2022
Nobunao Ikewaki, Yasunori Ikeue, Mitsuru Nagataki, Gene Kurosawa, Vidyasagar Devaprasad Dedeepiya, Mathaiyan Rajmohan, Suryaprakash Vaddi, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel J. K. Abraham
In this study, we used an obese and diabetic mouse model to compare two strains of Aureobasidium pullulans (AFO-202 and N-163) produced beta-glucans (β-glucans), which alleviate lipotoxicity. Four groups of KK-Ay mice were used, with six subjects in each group. Group 1: sacrificed on day 0 for baseline values; Group 2: control (drinking water); Group 3: AFO-202 beta glucan—200 mg/kg/day; Group 4: ...... hiện toàn bộ
Assessment of vascular function in individuals with hyperglycemia: a cross-sectional study of glucose – induced changes in digital volume pulse
Journal of Diabetes & Metabolic Disorders - Tập 14 - Trang 1-8 - 2015
Fariba Alaei-Shahmiri, Yun Zhao, Jill Sherriff
Arterial stiffness is an independent risk factor for cardiovascular disease and its progression may be accelerated in the presence of hyperglycemia, either fasting or postprandial. The current study assessed vascular function in subjects with pre-diabetes hyperglycemia, using digital volume pulse analysis technique. We conducted a cross-sectional study examining vascular function in the fasting an...... hiện toàn bộ
The anti-inflammatory activity of probiotic Dadiah to activate Sirtuin-1 in inhibiting diabetic nephropathy progression
Journal of Diabetes & Metabolic Disorders - Tập 22 - Trang 1425-1442 - 2023
Rinita Amelia, Faridah Mohd Said, Farzana Yasmin, Harnavi Harun, Tofrizal Tofrizal
The activation of SIRT-1 in the kidney has become a new therapeutic target to increase resistance to many causal factors in DN development. Furthermore, antioxidative stress and anti-inflammation are essential to preventing renal fibrosis in DN. Therefore, finding “probiotic products” to treat and prevent DN is necessary. This study aimed to analyze the anti-inflammatory of probiotic dadiah to act...... hiện toàn bộ
Diabetes and tuberculosis: a review of the role of optimal glycemic control
Journal of Diabetes & Metabolic Disorders - Tập 11 - Trang 1-4 - 2012
Asfandyar Khan Niazi, Sanjay Kalra
Developing countries shoulder most of the burden of diabetes and tuberculosis. These diseases often coexist. Suboptimal control of diabetes predisposes the patient to tuberculosis, and is one of the common causes of poor response to anti-tubercular treatment. Tuberculosis also affects diabetes by causing hyperglycemia and causing impaired glucose tolerance. Impaired glucose tolerance is one of the...... hiện toàn bộ
The prevalence of uncontrolled diabetes mellitus in patients with type 2 diabetes: a multicenter cross-sectional study
Journal of Diabetes & Metabolic Disorders - Tập 22 - Trang 787-792 - 2023
Monir Lorestanifar, Masoomeh Mosayebi Molasaraei, Reyhaneh Jashaninejad, Saman Khoshmanesh, Amin Doosti-Irani
The prevalence of diabetes is increasing worldwide. Studies have shown that poor blood sugar control is associated with the complications of diabetes, we aimed to determine the prevalence of uncontrolled diabetes mellitus (UDM) and its related factors. This multicenter cross-sectional study was conducted in 2021 on type 2 diabetic patients in three cities; Rasht (in Gillan province), Borujerd (in ...... hiện toàn bộ
Gongronema latifolium leaf extract modulates hyperglycaemia, inhibits redox imbalance and inflammation in alloxan-induced diabetic nephropathy
Journal of Diabetes & Metabolic Disorders - Tập 19 Số 1 - Trang 469-481 - 2020
Oluwafemi Adeleke Ojo, Olukemi Adetutu Osukoya, Lisa Ilobekemen Ekakitie, Basiru Olaitan Ajiboye, Babatunji Emmanuel Oyinloye, Precious Eseose Agboinghale, Abidemi Paul Kappo
Adding to the spectrum of insulin sensitive populations for mixed meal tolerance test glucose reliability assessment
Journal of Diabetes & Metabolic Disorders - Tập 15 - Trang 1-4 - 2016
Sabina Paglialunga, Angelica Guerrero, Julie M. Roessig, Paul Rubin, Clayton A. Dehn
As a measure of insulin sensitivity, the mixed meal tolerance test (MMTT) is a simple technique that can provide robust results. The assay consists of examining plasma glucose, insulin and C-peptide prior to and following the consumption of a test meal. While this procedure has been used in clinical research for several years, there is no set standard protocol, and only until recently has the reli...... hiện toàn bộ
Prospective of managing impaired brain insulin signalling in late onset Alzheimers disease with excisting diabetic drugs
Journal of Diabetes & Metabolic Disorders - Tập 18 Số 1 - Trang 229-242 - 2019
Gifty M Jojo, Gowthamarajan Kuppusamy, Kousalya Selvaraj, Uday Krishna Baruah
Association of cardiac autonomic neuropathy with arterial stiffness in type 2 diabetes mellitus patients
Journal of Diabetes & Metabolic Disorders - Tập 12 - Trang 1-6 - 2013
Ataollah Bagherzadeh, Afshin Nejati-Afkham, Yaser Tajallizade-Khoob, Akbar Shafiee, Farshad Sharifi, Morteza Abdar Esfahani, Zohre Badamchizade, Sudabeh Alatab, Hossein Fakhrzadeh
Diabetic patients are at the risk of cardiac autonomic neuropathy (CAN) and arterial stiffness. This study aimed to investigate the association of heart rate variability (HRV) as an index for CAN and pulse wave velocity (PWV) as an index for arterial stiffness. Uncomplicated diabetes type-2 patients who had no apparent history of cardiovascular condition underwent HRV and PWV measurements and the ...... hiện toàn bộ
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