Vectorization of the general Monte Carlo classical trajectory program VENUSJournal of Computational Chemistry - Tập 12 Số 8 - Trang 1014-1024 - 1991
Xiche Hu, William L. Hase, Tony Pirraglia
AbstractThe general chemical dynamics computer program VENUS is used to perform classical trajectory simulations for large polyatomic systems, with many atoms and complicated potential energy functions. To simulate an ensemble of many trajectories requires a large amount of CPU time. Since each trajectory is independent, it is possible to parallel process a large s...... hiện toàn bộ
Comparison of a posteriori and a priori BSSE correction schemes for SCF intermolecular energiesJournal of Computational Chemistry - Tập 14 Số 4 - Trang 401-409 - 1993
P. Valiron, Ágnes Vibók, I. Mayer
AbstractA systematic SCF study has been undertaken to compare the conventional a posteriori Boys–Bernardi BSSE correction scheme with our recent CHA/F method in which BSSE is excluded in a priori manner. Potential curves have been obtained for nine simple hydrogen‐bonded systems by using nine different basis set...... hiện toàn bộ
Validity of the Hammond postulate and constraints on general one‐dimensional reaction barriersJournal of Computational Chemistry - Tập 9 Số 7 - Trang 728-744 - 1988
Gustavo A. Arteca, Paul G. Mezey
AbstractThe Hammond postulate is a useful, qualitative tool that interrelates structural similarities between reactants, transition structures, and products with the exo‐ or endothermicity of reactions. It applies to most chemical reactions, although several exceptions are known. In this study the following problem is addressed: is it possible to formulate conditio...... hiện toàn bộ
Fast, efficient generation of high‐quality atomic charges. AM1‐BCC model: II. Parameterization and validationJournal of Computational Chemistry - Tập 23 Số 16 - Trang 1623-1641 - 2002
Araz Jakalian, D. B. Jack, Christopher I. Bayly
AbstractWe present the first global parameterization and validation of a novel charge model, called AM1‐BCC, which quickly and efficiently generates high‐quality atomic charges for computer simulations of organic molecules in polar media. The goal of the charge model is to produce atomic charges that emulate the HF/6‐31G* electrostatic potential (ESP) of a molecule...... hiện toàn bộ
SwissParam: A fast force field generation tool for small organic moleculesJournal of Computational Chemistry - Tập 32 Số 11 - Trang 2359-2368 - 2011
Vincent Zoete, Michel A. Cuendet, Aurélien Grosdidier, Olivier Michielin
AbstractThe drug discovery process has been deeply transformed recently by the use of computational ligand‐based or structure‐based methods, helping the lead compounds identification and optimization, and finally the delivery of new drug candidates more quickly and at lower cost. Structure‐based computational methods for drug discovery mainly involve ligand‐protein...... hiện toàn bộ