Journal of Cell Communication and Signaling

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Sequence features, structure, ligand interaction, and diseases in small leucine rich repeat proteoglycans
Journal of Cell Communication and Signaling - Tập 15 - Trang 519-531 - 2021
Norio Matsushima, Hiroki Miyashita, Robert H. Kretsinger
Small leucine rich repeat proteoglycans (SLRPs) are a group of active components of the extracellular matrix in all tissues. SLRPs bind to collagens and regulate collagen fibril growth and fibril organization. SLRPs also interact with various cytokines and extracellular compounds, which lead to various biological functions such cell adhesion and signaling, proliferation, and differentiation. Mutat... hiện toàn bộ
CCN3 and bone marrow cells
Journal of Cell Communication and Signaling - Tập 3 - Trang 135-145 - 2009
Ken-ichi Katsube, Saki Ichikawa, Yuko Katsuki, Tasuku Kihara, Masanori Terai, Lester F. Lau, Yoshihiro Tamamura, Shin’ichi Takeda, Akihiro Umezawa, Kei Sakamoto, Akira Yamaguchi
CCN3 expression was observed in a broad variety of tissues from the early stage of development. However, a kind of loss of function in mice (CCN3 del VWC domain -/-) demonstrated mild abnormality, which indicates that CCN3 may not be critical for the normal embryogenesis as a single gene. The importance of CCN3 in bone marrow environment becomes to be recognized by the studies of hematopoietic ste... hiện toàn bộ
Interleukin-1 alpha and high mobility group box-1 secretion in polyinosinic:polycytidylic-induced colorectal cancer cells occur via RIPK1-dependent mechanism and participate in tumourigenesis
Journal of Cell Communication and Signaling - Tập 17 - Trang 189-208 - 2022
Kim Jun Cheng, Elsa Haniffah Mejia Mohamed, Saiful Effendi Syafruddin, Zaridatul Aini Ibrahim
Pathogenic infections have significant roles in the pathogenesis of colorectal cancer (CRC). These infections induce the secretion of various damage-associated molecular patterns (DAMPs) including interleukin-1 alpha (IL-1α) and high mobility group box-1 (HMGB1). Despite their implication in CRC pathogenesis, the mechanism(s) that modulate the secretion of IL-1α and HMGB1, along with their roles i... hiện toàn bộ
CCN proteins are part of a multilayer complex system: a working model
Journal of Cell Communication and Signaling - Tập 13 - Trang 437-439 - 2019
Bernard Perbal
Platelet-lymphocyte co-culture serves as an ex vivo platform of dynamic heterotypic cross-talk
Journal of Cell Communication and Signaling - - 2022
Samara Albayati, Li N, Amanda J. Unsworth, Elisabetta Liverani
ATPase vận chuyển canxi và đồng: sự tương đồng và khác biệt trong cơ chế truyền đạt và tín hiệu Dịch bởi AI
Journal of Cell Communication and Signaling - Tập 5 - Trang 227-237 - 2011
Giuseppe Inesi
ATPase vận chuyển canxi và ATPase vận chuyển đồng đều là các thành viên của gia đình P-ATPase và giữ lại cơ chế xúc tác tương tự cho việc sử dụng ATP, bao gồm việc chuyển phosphoryl trung gian đến một dư lượng aspartyl được bảo tồn, sự dịch chuyển theo hướng của cation bị ràng buộc, và sự phân hủy thủy phân cuối cùng của Pi. Cả hai ATPase đều trải qua những thay đổi hình dạng protein đồng thời với... hiện toàn bộ
#ATPase #canxi #đồng #cơ chế truyền đạt #tín hiệu #phosphoryl hóa #màng plasma
Cross- species communication in bacterial world
Journal of Cell Communication and Signaling - Tập 11 - Trang 187-190 - 2017
Sarangam Majumdar, Sukla Pal
Biofilms are the compact association of micro organisms and the communication processes in these biofilms are always a wonder. Electrical and chemical signaling mechanism are the key to understand the bacterial communication network. Quorum sensing so far has been able to explain the coordinated motion of bacteria through its chemical signaling mechanism. Bacteria residing within biofilm communiti... hiện toàn bộ
A sticky situation: CCN1 promotes both proliferation and apoptosis of cancer cells
Journal of Cell Communication and Signaling - Tập 4 - Trang 71-72 - 2009
Andrew Leask
Members of the CCN family of matricellular signaling regulators promote cell adhesion through integrins and heparan sulfate-containing proteoglycans. A paradox of the CCN field is that, depending on the set of circumstances examined, individual CCN molecules can have quite different, and often opposing, effects. In a recent report, Franzen and colleagues (Mol Cancer Res. 7:1045–1055, 2009) show us... hiện toàn bộ
Quinacrine inhibits cMET-mediated metastasis and angiogenesis in breast cancer stem cells
Journal of Cell Communication and Signaling - Tập 17 Số 4 - Trang 1371-1388 - 2023
Biswajit Das, Chinmayee Sethy, Subhajit Chatterjee, Somya Ranjan Dash, Saptarshi Sinha, Subarno Paul, Kunal Goutam, Chanakya Nath Kundu
CCN2 is required for recruitment of Sox2-expressing cells during cutaneous tissue repair
Journal of Cell Communication and Signaling - Tập 9 - Trang 341-346 - 2014
Matthew Tsang, Andrew Leask
Connective tissue growth factor (CTGF/CCN2), a member of the CCN family of matricellular proteins is upregulated in both fibrosis as well as tissue repair. Recently, we showed that, in mice, CCN2 expression by fibroblasts was required for dermal fibrogenesis, but not for cutaneous tissue repair. Lineage tracing analysis linked the ability of CCN2 to promote fibrosis to the requirement for CCN2 to ... hiện toàn bộ
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