CCN3 and bone marrow cellsJournal of Cell Communication and Signaling - Tập 3 - Trang 135-145 - 2009
Ken-ichi Katsube, Saki Ichikawa, Yuko Katsuki, Tasuku Kihara, Masanori Terai, Lester F. Lau, Yoshihiro Tamamura, Shin’ichi Takeda, Akihiro Umezawa, Kei Sakamoto, Akira Yamaguchi
CCN3 expression was observed in a broad variety of tissues from the early stage of development. However, a kind of loss of function in mice (CCN3 del VWC domain -/-) demonstrated mild abnormality, which indicates that CCN3 may not be critical for the normal embryogenesis as a single gene. The importance of CCN3 in bone marrow environment becomes to be recognized by the studies of hematopoietic ste...... hiện toàn bộ
Sulfatase-1 knockdown promotes in vitro and in vivo aggressive behavior of murine hepatocarcinoma Hca-P cells through up-regulation of mesothelinJournal of Cell Communication and Signaling - - 2018
Salma Abdi Mahmoud, Mohammed Mohammed Ibrahim, Ahmed Hago Musa, Yühong Huang, Jun Zhang, Jingwen Wang, Yiran Wei, Li Wang, Shunting Zhou, Boyi Xin, Wei Xuan, Jianwu Tang
CCN2/decorin interactions: a novel approach to combating fibrosis?Journal of Cell Communication and Signaling - Tập 5 - Trang 249-250 - 2011
Andrew Leask
CCN2 (connective tissue growth factor, CTGF), a member of the CCN family is overexpressed in fibrotic disease and is essential for the development of experimental fibrosis. Drugs targeting CCN2 action may therefore prove to be useful anti-fibrotic approaches. CCN2 acts via integrins and heparan sulfate-containing proteoglycans (HSPGs). In a recent study, Vial and colleagues (2011) show that decori...... hiện toàn bộ
Global transcriptomic analysis of induced cardiomyocytes predicts novel regulators for direct cardiac reprogrammingJournal of Cell Communication and Signaling - Tập 11 - Trang 193-204 - 2017
Mahmood Talkhabi, Seyed Morteza Razavi, Ali Salari
Heart diseases are the most significant cause of morbidity and mortality in the world. De novo generated cardiomyocytes (CMs) are a great cellular source for cell-based therapy and other potential applications. Direct cardiac reprogramming is the newest method to produce CMs, known as induced cardiomyocytes (iCMs). During a direct cardiac reprogramming, also known as transdifferentiation, non-card...... hiện toàn bộ
Questionable papers in citation databases as an issue for literature reviewJournal of Cell Communication and Signaling - Tập 11 - Trang 181-185 - 2017
Mehdi Dadkhah, Mohammad Lagzian, Glenn Borchardt
In recent years, the academic world has been faced with much academic misconduct. Examples involve plagiarizing papers, manipulating data, and launching predatory or hijacked journals. The literature exposing these activities is growing exponentially, and so is the presentation of criteria or guidelines for counteracting the problem. Most of the research is focused on predatory or hijacked journal...... hiện toàn bộ
An assembly of TROP2-mediated signaling eventsJournal of Cell Communication and Signaling - Tập 17 - Trang 1105-1111 - 2023
Shubham Sukerndeo Upadhyay, Rex Devasahayam Arokia Balaya, Sakshi Sanjay Parate, Shobha Dagamajalu, T. S. Keshava Prasad, Rohan Shetty, Rajesh Raju
Trophoblast cell surface antigen 2 (TROP2) is a calcium-transducing transmembrane protein mainly involved in embryo development. The aberrant expression of TROP2 is observed in numerous cancers, including triple-negative breast cancer, gastric, colorectal, pancreatic, squamous cell carcinoma of the oral cavity, and prostate cancers. The main signaling pathways mediated by TROP2 are calcium signali...... hiện toàn bộ
Role of prostaglandins in fibroblast activation and fibrosisJournal of Cell Communication and Signaling - Tập 4 Số 2 - Trang 75-77 - 2010
Stratton, Richard, Shiwen, Xu
Fibroblasts release prostaglandins and express a range of prostanoid receptors. However the importance of prostaglandins in fibroblast biology have not been fully explored. Our studies showed that the prostaglandin metabolite PGI2 blocks the activation of fibroblasts, antagonising the induction of Ras/MEK/ERK signalling by TGFβ. Endogenous PGI2 acts so as to limit the activation of fibroblasts fol...... hiện toàn bộ