Using ultrasound-targeted microbubble destruction to enhance radiotherapy of glioblastomaJournal of Cancer Research and Clinical Oncology - Tập 147 - Trang 1355-1363 - 2021
Chanjuan Peng, Yong Wu, Yang Yang, Ningning Li, Xi Chen, Linhui Gu, Dong Xu, Chen Yang
To investigate the efficacy and mechanism of ultrasound-targeted microbubble destruction (UTMD) combined with radiotherapy (XRT) on glioblastoma. The enhanced radiosensitization by UTMD was assessed through colony formation and cell apoptosis in Human glioblastoma cells (U87MG). Subcutaneous transplantation tumors in 24 nude mice implanted with U87MG cells were randomly assigned to 4 different tre...... hiện toàn bộ
Experiences with the human tumor colony-forming assay in gynecologic malignanciesJournal of Cancer Research and Clinical Oncology - Tập 110 - Trang 234-237 - 1985
Günter E. Umbach, Judith Poethen, Heino v. Matthiessen, Hans Georg Bender, Ursula Koldovsky
Tumor samples from 74 patients with gynecologic malignancies including breast cancer were processed in a soft agar colony-forming assay. None of the samples resulted in a pure single cell suspension. Of the 10 samples meeting our criteria of evaluability for chemosensitivity testing, only 5 samples showed in vitro sensitivity to any drug. Of the 3 evaluable correlations between in vitro and in viv...... hiện toàn bộ
Clinical identification of colorectal cancer patients benefiting from adjuvant uracil–tegafur (UFT): a randomized controlled trialJournal of Cancer Research and Clinical Oncology - Tập 134 - Trang 1319-1323 - 2008
Masashi Fujii, Tadatoshi Takayama, Mitsugu Kochi
A randomized controlled trial was conducted to determine whether pathologic necrosis in response to preoperative treatment with uracil–tegafur(UFT) could be used to identify patients with colorectal cancer most likely to benefit from postoperative adjuvant therapy with the drug. The 152 patients with colorectal cancer who received preoperative UFT at a dose of 600 mg/day for at least 10 days were ...... hiện toàn bộ