The hemostatic capability, adhesion ability and biocompatibility of chitosan
sponges were compared with commercial collagen sponges. The chitosan sponges
were briefly immersed in an aqueous 20% ammonia solution before being applied to
a rabbit cervical vein wound. The total amount of bleeding from the injured
veins until hemostasis was similar for both chitosan and collagen sponges. The
complete h... hiện toàn bộ
The effect of the film-forming solution pH on the triple-helix content, thermal
stability, and mechanical properties of gelatin films was investigated. The
films were prepared from solutions at different pHs of type A pigskin gelatin,
and their mechanical characteristics were determined. At pHs higher than 9 and
lower than 5, Young’s modulus, E, and the stress at break, σb, of the films
decreased ... hiện toàn bộ
We have studied the interaction of macromolecular anticancer agent SMANCS, a
conjugate of partially half-butyl-esterified styrene-co-maleic acid
polymer[butyl-SMA]- and neocarzinostatin (NCS), with various serum proteins by
the fluorescence polarization method. Comparatively strong binding of
FITC-labeled SMANCS (F-SMANCS) to human serum albumin (HSA) and weak binding to
fibrinogen were observed, ... hiện toàn bộ
Francesco M. Veronese, Cristina Mammucari, Paolo Caliceti, Oddone Schiavon, S. Lora
Model proteins of therapeutic interest, ribonuclease, superoxide dismutase,
catalase and albumin, extensively PEGylated with linear 5,000 Mw PEG, were
entrapped in PVA hydrogels (31,000-50,000 Mw) by means of a cryogel procedure
and the rate of release was evaluated. All of the PEGylated proteins were
released from the gel, but at a lower rate than the unmodified proteins. The
rate for both native... hiện toàn bộ
Assunta Borzacchiello, Laura Mayol, Luigi Ambrosio, Ola Gärskog, Åke Dahlqvist
The investigation of vocal folds viscoelastic properties in an animal model
(rabbit) after injection of various augmentation substances, 6 months after
injection, is reported. The injected materials were: hyaluronan-based materials
(Hylan B gel and Deflux®), cross-linked collagen (Zyplast®) and
polytetrafluoroethylene (Teflon®). Rheological properties of the augmentation
substances were also evalu... hiện toàn bộ