Journal of Applied Physiology

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Shunt and ventilation-perfusion distribution during partial liquid ventilation in healthy piglets
Journal of Applied Physiology - Tập 82 Số 3 - Trang 933-942 - 1997
Elisabeth Mates, J. Hildebrandt, J. Craig Jackson, Peter Tarczy‐Hornoch, Michael P. Hlastala
Mates, Elisabeth A., Jacob Hildebrandt, J. Craig Jackson, Peter Tarczy-Hornoch, and Michael P. Hlastala. Shunt and ventilation-perfusion distribution during partial liquid ventilation in healthy piglets. J. Appl. Physiol.82(3): 933–942, 1997.—Replacing gas in the lung with perfluorocarbon fluids (PFC) and periodically ventilating with a gas [partial liquid ventilation (PLV)] has been show...... hiện toàn bộ
Continuous Recording of Blood Oxygen Tensions by Polarography
Journal of Applied Physiology - Tập 6 Số 3 - Trang 189-193 - 1953
Leland C. Clark, Richard M. Wolf, Donald L. Granger, Zena Taylor
Ozone-induced airway hyperresponsiveness and loss of neuronal M2 muscarinic receptor function
Journal of Applied Physiology - Tập 76 Số 3 - Trang 1088-1097 - 1994
A. H. Schultheis, David Bassett, A.D. Fryer
The effect of acute ozone exposure on the function of efferent parasympathetic nerves, M3 muscarinic receptors on airway smooth muscle, and inhibitory M2 muscarinic receptors on the parasympathetic nerves was studied. Immediately after exposure to 2.0 ppm ozone for 4 h, guinea pigs became hyperresponsive to electrical stimulation of the vagus nerves. The normal airway response to intraven...... hiện toàn bộ
Total respiratory tract deposition of fine micrometer-sized particles in healthy adults: empirical equations for sex and breathing pattern
Journal of Applied Physiology - Tập 101 Số 2 - Trang 401-412 - 2006
Chong S. Kim, Shu-Chieh Hu
Accurate dose estimation under various inhalation conditions is important for assessing both the potential health effects of pollutant particles and the therapeutic efficacy of medicinal aerosols. We measured total deposition fraction (TDF) of monodisperse micrometer-sized particles [particle diameter (Dp) = 1, 3, and 5 μm in diameter] in healthy adults (8 men and 7 w...... hiện toàn bộ
Positive end-expiratory pressure shifts left ventricular diastolic pressure-area curves
Journal of Applied Physiology - Tập 48 Số 4 - Trang 670-676 - 1980
J. B. Haynes, SA Carson, W. P. Whitney, Gary O. Zerbe, Thomas M. Hyers, Peter Steele
Positive end-expiratory pressure (PEEP) ventilation is frequently associated with reduction in cardiac output despite unchanged transmural left ventricular (LV) end-diastolic pressure. These findings have been interpreted to indicate decreased contractility, but could also be explained by altered LV diastolic pressure-volume characteristics. To study this possibility, radiopaque markers w...... hiện toàn bộ
Effects of pressure on uptake and release of calcium by brain synaptosomes
Journal of Applied Physiology - Tập 60 Số 4 - Trang 1446-1450 - 1986
Sara C. Gilman, K.K. Kumaroo, John M. Hallenbeck
Uptake of radioactive calcium from guinea pig brain fractions enriched in synaptosomes could be significantly and reproducibly decreased by exposure to high pressure. Calcium efflux from preloaded synaptosomes was unaffected by pressure exposure. It was hypothesized that the development of pressure-induced encephalopathy may be related to an effect of pressure on the central nervous syste...... hiện toàn bộ
M1/70 attenuates blood-borne neutrophil oxidants, activation, and myofiber damage following stretch injury
Journal of Applied Physiology - Tập 95 Số 3 - Trang 969-976 - 2003
Stacey Brickson, Lili Ji, Kathleen Schell, Ronke M. Olabisi, Barbara St. Pierre Schneider, Thomas M. Best
The purpose of this study was to determine the role of the CD11b-dependent respiratory burst in neutrophil oxidant generation and activation, interleukin-8 (IL-8) production, and myofiber damage after muscle stretch injury by using the monoclonal antibody M1/70 to block this pathway. Twelve male New Zealand White rabbits were randomly assigned to a treatment group: M1/70 ( n = 6), IgG isot...... hiện toàn bộ
Determination of oxygen consumption by use of the paramagnetic oxygen analyzer.
Journal of Applied Physiology - Tập 33 Số 2 - Trang 261-263 - 1972
Robert W. Hill
A computer model of human thermoregulation for a wide range of environmental conditions: the passive system
Journal of Applied Physiology - Tập 87 Số 5 - Trang 1957-1972 - 1999
Dusan Fiala, Kevin J. Lomas, Martin Stohrer
A dynamic model predicting human thermal responses in cold, cool, neutral, warm, and hot environments is presented in a two-part study. This, the first paper, is concerned with aspects of the passive system: 1) modeling the human body, 2) modeling heat-transport mechanisms within the body and at its periphery, and 3) the numerical procedure. A paper in preparation will describe the active ...... hiện toàn bộ
Metabolic and vasomotor insulative responses occurring on immersion in cold water
Journal of Applied Physiology - Tập 58 Số 3 - Trang 964-977 - 1985
L. Strong, Gin K. Gee, Ralph F. Goldman
Twenty male volunteers (17–28 yr of age) exhibiting a range of body weights (60 kg less than or equal to Wt less than or equal to 95 kg) and body fat (7% less than or equal to BF less than or equal to 23%) underwent total immersion while at rest in water between 36 and 20 degrees C. The metabolic heat production measured as a function of time and water temperature was converted to explici...... hiện toàn bộ
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