Effects of pressure on uptake and release of calcium by brain synaptosomes

Journal of Applied Physiology - Tập 60 Số 4 - Trang 1446-1450 - 1986
Sara C. Gilman, K.K. Kumaroo, John M. Hallenbeck

Tóm tắt

Uptake of radioactive calcium from guinea pig brain fractions enriched in synaptosomes could be significantly and reproducibly decreased by exposure to high pressure. Calcium efflux from preloaded synaptosomes was unaffected by pressure exposure. It was hypothesized that the development of pressure-induced encephalopathy may be related to an effect of pressure on the central nervous system calcium transport system.

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