UPLC/FT-ICR MS-based high-resolution platform for determining the geographical origins of raw propolis samplesJournal of Analytical Science and Technology - Tập 10 - Trang 1-12 - 2019
Cho Hyun Kim, Mee Young Kim, Seung-Wan Lee, Kyoung-Soon Jang
In this study, we demonstrate a high-resolution 15 Tesla Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry coupled with a reverse-phase ultra-performance liquid chromatography (RP-UPLC) system for determining the geographical origins of raw propolis samples. The UPLC/FT-ICR MS-based high-resolution platform was validated on the ethanol-extracted propolis (EEP) from various propo...... hiện toàn bộ
Bioanalysis of alpelisib using liquid chromatography–tandem mass spectrometry and application to pharmacokinetic studyJournal of Analytical Science and Technology - Tập 13 - Trang 1-13 - 2022
Seop Lee, Min-Soo Kim, Jong-Woo Jeong, Jung-woo Chae, Tae-Sung Koo, Han-Joo Maeng, Suk-Jae Chung, Kyeong-Ryoon Lee, Yoon-Jee Chae
Alpelisib is the first alpha-specific phosphatidylinositol-3-kinase (PI3K) inhibitor indicated for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative, PI3K catalytic subunit alpha-mutated, advanced, or metastatic breast cancer. Substantial attempts have been made to extend its clinical use to other types of cancer. Analytical methods proven to accurately ...... hiện toàn bộ
A rapid assessment method for determination of iodate in table salt samplesJournal of Analytical Science and Technology - Tập 4 - Trang 1-6 - 2013
Preeti S Kulkarni, Satish D Dhar, Sunil D Kulkarni
In the present work, a simple and rapid method for determination of iodate is described. Iodometric reaction between iodate, excess iodide, and acid has been used, and the iodine liberated is allowed to react with variamine blue (VB) dye in the presence of sodium acetate to yield a violet-colored species. A calibration curve was obtained in the concentration range of 2 to 30 μg of iodate in a fina...... hiện toàn bộ
UHPLC‐Q‐TOF‐MS/MS‐guided dereplication to study chemical constituents of Hedera nepalensis leaves in northern VietnamJournal of Analytical Science and Technology - Tập 14 - Trang 1-13 - 2023
Pham Hong Ngoc, Tran Chieu An, Nguyen Tuan Hiep, Tran Phan Huynh Nhu, Le Ngoc Hung, Nguyen Quang Trung, Bui Quang Minh, Phung Van Trung
Hedera nepalensis is commonly used as a traditional medicine for the treatment of several diseases. In this research, the efficient characterization of chemical constituents, especially triterpenoid saponins, contained in H. nepalensis extract was established by applying ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight tandem mass spectrometry method (UHPLC‐Q‐TOF‐MS/MS). As a...... hiện toàn bộ
A novel cysteine catalytic oxidation-based colorimetric approach for sensitive analysis of acute pancreatitis-related microRNAJournal of Analytical Science and Technology - Tập 14 - Trang 1-7 - 2023
Mingwei Gong, Guoyan Jiang, Yuan Rong, Zeping Yang, Dong She, Chunhong Sun
It is essential to establish simple, sensitive and accurate quantitative approaches for microRNAs (miRNAs) identification due to its crucial roles in a variety of physiological and pathological processes. Herein, we propose a novel RCA-based colorimetric method for sensitive and reliable miRNA analysis. In this approach, cyclization of the padlock sequence by miRNA-21 initiates the RCA to produce ...... hiện toàn bộ