Journal of Analytical Science and Technology

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UPLC/FT-ICR MS-based high-resolution platform for determining the geographical origins of raw propolis samples
Journal of Analytical Science and Technology - Tập 10 - Trang 1-12 - 2019
Cho Hyun Kim, Mee Young Kim, Seung-Wan Lee, Kyoung-Soon Jang
In this study, we demonstrate a high-resolution 15 Tesla Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry coupled with a reverse-phase ultra-performance liquid chromatography (RP-UPLC) system for determining the geographical origins of raw propolis samples. The UPLC/FT-ICR MS-based high-resolution platform was validated on the ethanol-extracted propolis (EEP) from various propo...... hiện toàn bộ
Bioanalysis of alpelisib using liquid chromatography–tandem mass spectrometry and application to pharmacokinetic study
Journal of Analytical Science and Technology - Tập 13 - Trang 1-13 - 2022
Seop Lee, Min-Soo Kim, Jong-Woo Jeong, Jung-woo Chae, Tae-Sung Koo, Han-Joo Maeng, Suk-Jae Chung, Kyeong-Ryoon Lee, Yoon-Jee Chae
Alpelisib is the first alpha-specific phosphatidylinositol-3-kinase (PI3K) inhibitor indicated for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative, PI3K catalytic subunit alpha-mutated, advanced, or metastatic breast cancer. Substantial attempts have been made to extend its clinical use to other types of cancer. Analytical methods proven to accurately ...... hiện toàn bộ
A rapid assessment method for determination of iodate in table salt samples
Journal of Analytical Science and Technology - Tập 4 - Trang 1-6 - 2013
Preeti S Kulkarni, Satish D Dhar, Sunil D Kulkarni
In the present work, a simple and rapid method for determination of iodate is described. Iodometric reaction between iodate, excess iodide, and acid has been used, and the iodine liberated is allowed to react with variamine blue (VB) dye in the presence of sodium acetate to yield a violet-colored species. A calibration curve was obtained in the concentration range of 2 to 30 μg of iodate in a fina...... hiện toàn bộ
UHPLC‐Q‐TOF‐MS/MS‐guided dereplication to study chemical constituents of Hedera nepalensis leaves in northern Vietnam
Journal of Analytical Science and Technology - Tập 14 - Trang 1-13 - 2023
Pham Hong Ngoc, Tran Chieu An, Nguyen Tuan Hiep, Tran Phan Huynh Nhu, Le Ngoc Hung, Nguyen Quang Trung, Bui Quang Minh, Phung Van Trung
Hedera nepalensis is commonly used as a traditional medicine for the treatment of several diseases. In this research, the efficient characterization of chemical constituents, especially triterpenoid saponins, contained in H. nepalensis extract was established by applying ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight tandem mass spectrometry method (UHPLC‐Q‐TOF‐MS/MS). As a...... hiện toàn bộ
Environmentally preferable solvents promoted resolution of multi-component mixtures of amino acids: an approach to perform green chromatography
Journal of Analytical Science and Technology - Tập 4 - Trang 1-6 - 2013
Ali Mohammad, Asma Siddiq, Gaber E El-Desoky
Amino acids are the building blocks of proteins and found in structural tissues of the human body. Their deficiency may cause a number of diseases. Amino acids were analysed by the proposed thin layer chromatographic system using silica gel as stationary phase and Ethanol/70% aq. ethylene glycol/acetone (5:3:1) as mobile phase. Separations of some closely related amino acids from their quaternary,...... hiện toàn bộ
A novel cysteine catalytic oxidation-based colorimetric approach for sensitive analysis of acute pancreatitis-related microRNA
Journal of Analytical Science and Technology - Tập 14 - Trang 1-7 - 2023
Mingwei Gong, Guoyan Jiang, Yuan Rong, Zeping Yang, Dong She, Chunhong Sun
It is essential to establish simple, sensitive and accurate quantitative approaches for microRNAs (miRNAs) identification due to its crucial roles in a variety of physiological and pathological processes. Herein, we propose a novel RCA-based colorimetric method for sensitive and reliable miRNA analysis. In this approach, cyclization of the padlock sequence by miRNA-21 initiates the RCA to produce ...... hiện toàn bộ
Accessible analytical methodology for assessing workplace contamination of antineoplastic drugs in limited-resource oncology health-care settings
Journal of Analytical Science and Technology - Tập 7 - Trang 1-9 - 2016
Claudio Müller-Ramírez, Katherine Squibb, Melissa McDiarmid
Environmental monitoring of workplaces where antineoplastic drugs are handled constitutes an essential tool to assess occupational exposures among health-care workers. Consequently, availability of simple, sensitive, and affordable analytical methodologies is needed, particularly in health-care settings with limited resources that restrict environmental monitoring studies. Previously validated met...... hiện toàn bộ
HPLC-CUPRAC post-column derivatization method for the determination of antioxidants: a performance comparison between porous silica and core-shell column packing
Journal of Analytical Science and Technology - Tập 9 - Trang 1-9 - 2018
Syed A. Haque, Socrates Jose P. Cañete
An HPLC method employing a post-column derivatization strategy using the cupric reducing antioxidant capacity reagent (CUPRAC reagent) for the determining antioxidants in plant-based materials leverages the separation capability of regular HPLC approaches while allowing for detection specificity for antioxidants. Three different column types, namely core-shell and porous silica including two chemi...... hiện toàn bộ
Selective and sensitive determination of Cd(II) ions in various samples using a novel modified carbon paste electrode
Journal of Analytical Science and Technology - Tập 10 Số 1 - 2019
Refaat F. Aglan, Mostafa M. Hamed, Hosam M. Saleh
Isotopic variations of Sm, Gd, Er and Yb found in planetary materials caused by neutron-capture reactions in nature
Journal of Analytical Science and Technology -
Hiroshi Hidaka
AbstractThe isotopic shifts of 149Sm–150Sm and 157Gd–158Gd have often been observed in meteorites and lunar surface materials, because they result from the neutron-capture reactions associated with secondary neutrons produced by cosmic-ray irradiation. While the Sm and Gd isotopic s...... hiện toàn bộ
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