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SCOPUS (2017-2025)ESCI-ISI
2473-4039
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Cơ quản chủ quản: Wiley-Blackwell Publishing Ltd , WILEY
Lĩnh vực:
Endocrinology, Diabetes and MetabolismOrthopedics and Sports Medicine
Các bài báo tiêu biểu
Obesity Represses CYP2R1 , the Vitamin D 25‐Hydroxylase, in the Liver and Extrahepatic Tissues
Tập 4 Số 11 - 2020
ABSTRACTLow plasma level of 25‐hydroxyvitamin D (25‐OH‐D), namely vitamin D
deficiency, is associated with obesity and weight loss improves 25‐OH‐D status.
However, the mechanism behind obesity‐induced vitamin D deficiency remains
unclear. Here, we report that obesity suppresses the expression of cytochrome
P450 (CYP) 2R1, the main vitamin D 25‐hydroxylase, in both mice and humans. In
humans, weig...
Refracture and mortality following hospitalization for severe osteoporotic fractures: The Fractos Study
Tập 5 Số 7 - 2021
ABSTRACTSevere osteoporotic fractures (hip, proximal humerus, pelvic, vertebral
and multiple rib fractures) carry an increased risk of mortality. This
retrospective cohort study in the French national healthcare database aimed to
estimate refracture and mortality rates after severe osteoporotic fractures at
different sites, and to identify mortality‐related variables. A total of 356,895
patients h...
Administration of Denosumab Preserves Bone Mineral Density at the Knee in Persons With Subacute Spinal Cord Injury: Findings From a Randomized Clinical Trial
Tập 4 Số 8 - 2020
ABSTRACTPersons with neurologically motor‐complete spinal cord injury (SCI) have
a marked loss of bone mineral density (BMD) of the long bones of the lower
extremities, predisposing them to fragility fractures, especially at the knee.
Denosumab, a commercially available human monoclonal IgG antibody to receptor
activator of nuclear factor‐κB ligand (RANKL), may provide an
immunopharmacological sol...
The Real‐World Effect of 12 Months of Romosozumab Treatment on Patients With Osteoporosis With a High Risk of Fracture and Factors Predicting the Rate of Bone Mass Increase: A Multicenter Retrospective Study
Tập 6 Số 7 - 2022
ABSTRACTExcluding clinical trials, there is limited evidence on the effect of
12 months of romosozumab treatment on bone mineral density (BMD) increase in
real‐world clinical practice because its use has only been approved recently.
Thus, this study aimed to investigate the real‐world effect of 12 months of
romosozumab treatment on BMD increase and identify factors that predict the rate
of BMD inc...
Combination of DXA and BIS Predicts Jump Power Better Than Traditional Measures of Sarcopenia
Tập 5 Số 8 - 2021
ABSTRACTTraditional diagnostic criteria for sarcopenia use dual‐energy X‐ray
absorptiometry (DXA)‐measured appendicular lean mass (ALM), normalized to height
(ALM/ht2) or body mass index (ALM/BMI) to define low muscle mass. However,
muscle function declines with aging before the loss of muscle mass is detected
by ALM. This is likely due, in part, to qualitative muscle changes such as
extracellular...