Cefiderocol treatment for carbapenem-resistant Acinetobacter baumannii infection in the ICU during the COVID-19 pandemic: a multicentre cohort studyJAC-Antimicrobial Resistance - Tập 3 Số 4 - 2021
Renato Pascale, Zeno Pasquini, Michele Bartoletti, Luca Caiazzo, Giacomo Fornaro, Linda Bussini, Francesca Volpato, Elisa Marchionni, Matteo Rinaldi, Filippo Trapani, Chiara Temperoni, Paolo Gaibani, Simone Ambretti, Francesco Barchiesi, Pierluigi Viale, Maddalena Giannella
Abstract Objectives To analyse the impact of cefiderocol use on outcome in
patients admitted to the ICU for severe COVID-19 and further diagnosed with
carbapenem-resistant Acinetobacter baumannii (CR-Ab) infection. Methods
Retrospective multicentre observational study was performed at four Italian
hospitals, from January 2020 to April 2021. Adult patients admitted to ICU for
severe COVID-19 and fu... hiện toàn bộ
In vitroactivity of the siderophore cephalosporin, cefiderocol, against molecularly characterized, carbapenem-non-susceptible Gram-negative bacteria from EuropeJAC-Antimicrobial Resistance - Tập 2 Số 3 - 2020
Christopher Longshaw, Davide Manissero, Masakatsu Tsuji, Roger Echols, Yoshinori Yamano
AbstractObjectivesMany carbapenem-resistant (CR) Gram-negative (GN) pathogens
exhibit MDR, meaning few therapeutic options are available for CR-GN infections.
Cefiderocol, a siderophore cephalosporin, has demonstrated in vitro efficacy
against CR-GN bacteria. In the SIDERO-CR-2014–2016 surveillance study, European
clinical isolates comprising carbapenem-non-susceptible (CarbNS)
Enterobacterales an... hiện toàn bộ