The prognostic value of p53, Ki‐67 and matrix metalloproteinases MMP‐2 and MMP‐9 in transitional cell carcinoma of the renal pelvis and ureterInternational Journal of Urology - Tập 12 Số 11 - Trang 941-947 - 2005
Shuichi Kamijima, Toyofusa Tobe, Takahito Suyama, Takeshi Ueda, Tatsuo Igarashi, Tomohiko Ichikawa, Haruo Itô
Aim: To investigate the prognostic and predictive relevance of p53 protein,
Ki‐67 antigen, MMP‐2 and MMP‐9 in patients with transitional cell carcinoma
(TCC) of the upper urinary tract.Methods: The expression of p53 protein, Ki‐67
antigen, MMP‐2 and MMP‐9 was examined by immunohistochemistry in 69 patients
with TCC of the upper urinary tract. Correlation of p53, Ki‐67, MMP‐2 and MMP‐9
over‐express... hiện toàn bộ
Immunotherapy against metastatic renal cell carcinoma with mature dendritic cellsInternational Journal of Urology - Tập 14 Số 4 - Trang 277-283 - 2007
Akihiko Matsumoto, Kazutoshi Haraguchi, Tsuyoshi Takahashi, Takeshi Azuma, Yoshinobu Kanda, K. Tomita, Mineo Kurokawa, Seishi Ogawa, Koki Takahashi, Shigeru Chiba, Tadaichi Kitamura
Objective: We performed a clinical trial of immunotherapy using autologous
mature dendritic cells (DC) pulsed with autologous tumor lysate, for patients
with metastatic renal cell carcinoma (RCC).Methods: Patients with refractory
metastatic RCC were enrolled in the study. All of them received interferon
(IFN)‐α treatment after nephrectomy and were followed over 3 months prior to
this study. Auto... hiện toàn bộ
Treatment of androgen‐independent prostate cancer with dexamethasone: A prospective study in stage D2 patientsInternational Journal of Urology - Tập 8 Số 6 - Trang 290-294 - 2001
Takashi Sakaguchi, Noboru Kusaka, Tomoyasu Tsushima, Toyoko Yamato, Teruhisa Ohashi, Bunzo Suyama, Ryoji Arata, Yasutomo Nasu, Hiromi Kumon
AbstractPurpose:In order to evaluate the efficacy of dexamethasone in the
treatment of Japanese men with androgen‐independent prostate cancer, a
prospective study was conducted using prostate‐specific antigen (PSA) as a
primary end‐point.Methods:Nineteen Japanese men with stage D2
androgen‐independent prostate cancer were registered and treatment was started.
After ruling out anti‐androgen withdra... hiện toàn bộ
Hormone/Antihormone Withdrawal and Dexamethasone for Hormone‐Refractory Prostate CancerInternational Journal of Urology - Tập 5 Số 1 - Trang 44-47 - 1998
Tsutomu Nishiyama, Masahiro Terunuma
Background Flutamide withdrawal has been reported to benefit patients with
hormone‐refractory prostate cancer. Several studies have also demonstrated that
a combination of corticosteroids and testicular androgen ablation lowers serum
androgen levels and improves clinical response. The purpose of this study was to
examine the effect of withdrawal of oral hormonal agents and administration of
dexame... hiện toàn bộ
Circumcision with a novel disposable device in Chinese children: A randomized controlled trialInternational Journal of Urology - Tập 20 Số 2 - Trang 220-226 - 2013
Feng Pan, Lianjun Pan, Aixia Zhang, Yong Liu, Fenglei Zhang, Yutian Dai
ObjectivesTo compare the outcomes and complications of three methods of
circumcision in a Chinese pediatric population.MethodsA total of 120 children
were randomly assigned to three groups. Group I was submitted to circumcision
using the Shenghuan disposable device according to Yan's method; group II was
submitted to circumcision using the same device, but according to Peng's
methods; group III wa... hiện toàn bộ
The efficacy of laparoscopic radical nephrectomy for renal cell cancer in the elderly: An oncological outcome analysisInternational Journal of Urology - Tập 15 Số 7 - Trang 577-581 - 2008
Masahiko Harano, Masatoshi Eto, Akira Yokomizo, Katsunori Tatsugami, Masumitsu Hamaguchi, Seiji Naito
Objectives: The efficacy and outcome of a laparoscopic radical nephrectomy
(LRN) were retrospectively evaluated in patients aged ≥70 years, and the results
were compared with those obtained from patients younger than 70 years undergoing
laparoscopic surgery for the same indications.Methods: Data were collected for
all patients undergoing an LRN for renal cell carcinoma between March 1999 and
Nov... hiện toàn bộ
Correlation of Allelic Loss of the P53 Gene and Tumor Grade, Stage, and Malignant Progression in Bladder CancerInternational Journal of Urology - Tập 4 Số 1 - Trang 74-78 - 1997
Masakazu Tsutsumi, Kokichi Sugano, Kensei Yamaguchi, Tadao Kakizoe, Hideyuki Akaza
Background We examined loss of heterozygosity (LOH) of the P53 gene in bladder
cancer, and investigated the role of the P53 gene on malignant progression of
papillary tumors. In addition, the clonality of recurrent bladder cancer was
examined. Methods LOH of the P53 gene was analyzed in 67 bladder cancers from 47
patients. DNA was extracted from formalin‐fixed, paraffin‐embedded tissues,
amplified... hiện toàn bộ
Inverse correlation of microvessel density with metastasis and prognosis in renal cell carcinomaInternational Journal of Urology - Tập 11 Số 11 - Trang 948-953 - 2004
Tetsuya Imao, Masayuki Egawa, Hiroshi Takashima, Kiyoshi Koshida, Mikio Namiki
AbstractBackground: Although a correlation between microvessel density (MVD) and
tumor aggressiveness has been established for several malignancies, the data for
renal cell carcinoma (RCC) is conflicting. In order to clarify the significance
of MVD, we investigated the relationships between MVD and tumor stage, grade,
size, occurrence of metastasis and patient survival.Methods: Tumor specimens
fro... hiện toàn bộ