International Journal of Urology

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The prognostic value of p53, Ki‐67 and matrix metalloproteinases MMP‐2 and MMP‐9 in transitional cell carcinoma of the renal pelvis and ureter
International Journal of Urology - Tập 12 Số 11 - Trang 941-947 - 2005
Shuichi Kamijima, Toyofusa Tobe, Takahito Suyama, Takeshi Ueda, Tatsuo Igarashi, Tomohiko Ichikawa, Haruo Itô
Aim: To investigate the prognostic and predictive relevance of p53 protein, Ki‐67 antigen, MMP‐2 and MMP‐9 in patients with transitional cell carcinoma (TCC) of the upper urinary tract.Methods: The expression of p53 protein, Ki‐67 antigen, MMP‐2 and MMP‐9 was examined by immunohistochemistry in 69 patients with TCC of the upper...... hiện toàn bộ
Roles of p53 and MDM2 in tumor proliferation and determination of the prognosis of transitional cell carcinoma of the renal pelvis and ureter
International Journal of Urology - Tập 7 Số 12 - Trang 457-463 - 2000
Hiroshi Hashimoto, Yoichi Sue, Yuji Saga, Masayuki Tokumitsu, Sunao Yachiku
Abstract Background The significance of p53 overexpression for the prognosis of transitional cell carcinoma (TCC) of the renal pelvis and ureter remains controversial. Simultaneous evaluation of p53 and MDM2 may enable better prediction of tumor proliferation and patient prognosis than that obtained with evaluation of p53 alone.... hiện toàn bộ
Immunotherapy against metastatic renal cell carcinoma with mature dendritic cells
International Journal of Urology - Tập 14 Số 4 - Trang 277-283 - 2007
Akihiko Matsumoto, Kazutoshi Haraguchi, Tsuyoshi Takahashi, Takeshi Azuma, Yoshinobu Kanda, K. Tomita, Mineo Kurokawa, Seishi Ogawa, Koki Takahashi, Shigeru Chiba, Tadaichi Kitamura
Objective:  We performed a clinical trial of immunotherapy using autologous mature dendritic cells (DC) pulsed with autologous tumor lysate, for patients with metastatic renal cell carcinoma (RCC).Methods:  Patients with refractory metastatic RCC were enrolled in the study. All of them received interferon (IFN)‐α treatment afte...... hiện toàn bộ
Hormone/Antihormone Withdrawal and Dexamethasone for Hormone‐Refractory Prostate Cancer
International Journal of Urology - Tập 5 Số 1 - Trang 44-47 - 1998
Tsutomu Nishiyama, Masahiro Terunuma
Background Flutamide withdrawal has been reported to benefit patients with hormone‐refractory prostate cancer. Several studies have also demonstrated that a combination of corticosteroids and testicular androgen ablation lowers serum androgen levels and improves clinical response. The purpose of this study was to examine the effect of withdrawal of oral hormonal age...... hiện toàn bộ
Treatment of androgen‐independent prostate cancer with dexamethasone: A prospective study in stage D2 patients
International Journal of Urology - Tập 8 Số 6 - Trang 290-294 - 2001
Takashi Sakaguchi, Noboru Kusaka, Tomoyasu Tsushima, Toyoko Yamato, Teruhisa Ohashi, Bunzo Suyama, Ryoji Arata, Yasutomo Nasu, Hiromi Kumon
AbstractPurpose:In order to evaluate the efficacy of dexamethasone in the treatment of Japanese men with androgen‐independent prostate cancer, a prospective study was conducted using prostate‐specific antigen (PSA) as a primary end‐point.Methods:Ni...... hiện toàn bộ
Circumcision related to urinary tract infections, sexually transmitted infections, human immunodeficiency virus infections, and penile and cervical cancer
International Journal of Urology - Tập 20 Số 8 - Trang 769-775 - 2013
Yutaro Hayashi, Kenjiro Kohri
AbstractMale circumcision has been carried out as a prophylactic measure against future diseases, as well as a rite of passage due to religious practice and definite medical indication. The present review discusses the benefits of male circumcision on the prevention of urinary tract infections, and the importance of circumcision in congenital urinary system anomali...... hiện toàn bộ
Circumcision with a novel disposable device in Chinese children: A randomized controlled trial
International Journal of Urology - Tập 20 Số 2 - Trang 220-226 - 2013
Feng Pan, Lianjun Pan, Aixia Zhang, Yong Liu, Fenglei Zhang, Yutian Dai
ObjectivesTo compare the outcomes and complications of three methods of circumcision in a Chinese pediatric population.MethodsA total of 120 children were randomly assigned to three groups. Group  hiện toàn bộ
The efficacy of laparoscopic radical nephrectomy for renal cell cancer in the elderly: An oncological outcome analysis
International Journal of Urology - Tập 15 Số 7 - Trang 577-581 - 2008
Masahiko Harano, Masatoshi Eto, Akira Yokomizo, Katsunori Tatsugami, Masumitsu Hamaguchi, Seiji Naito
Objectives:  The efficacy and outcome of a laparoscopic radical nephrectomy (LRN) were retrospectively evaluated in patients aged ≥70 years, and the results were compared with those obtained from patients younger than 70 years undergoing laparoscopic surgery for the same indications.Methods:  Data were collected for all patient...... hiện toàn bộ
Correlation of Allelic Loss of the P53 Gene and Tumor Grade, Stage, and Malignant Progression in Bladder Cancer
International Journal of Urology - Tập 4 Số 1 - Trang 74-78 - 1997
Masakazu Tsutsumi, Kokichi Sugano, Kensei Yamaguchi, Tadao Kakizoe, Hideyuki Akaza
Background We examined loss of heterozygosity (LOH) of the P53 gene in bladder cancer, and investigated the role of the P53 gene on malignant progression of papillary tumors. In addition, the clonality of recurrent bladder cancer was examined. Methods LOH of the ... hiện toàn bộ
Inverse correlation of microvessel density with metastasis and prognosis in renal cell carcinoma
International Journal of Urology - Tập 11 Số 11 - Trang 948-953 - 2004
Tetsuya Imao, Masayuki Egawa, Hiroshi Takashima, Kiyoshi Koshida, Mikio Namiki
AbstractBackground: Although a correlation between microvessel density (MVD) and tumor aggressiveness has been established for several malignancies, the data for renal cell carcinoma (RCC) is conflicting. In order to clarify the significance of MVD, we investigated the relationships between MVD and tumor stage, grade, size, occurrence of meta...... hiện toàn bộ
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