International Journal of Clinical Oncology

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Clinical features and distribution of the APC variant in duodenal and ampullary polyps in patients with familial adenomatous polyposis: a multicenter retrospective cohort study in Japan
International Journal of Clinical Oncology - - Trang 1-10 - 2023
Yasuyuki Miyakura, Tatsuro Yamaguchi, Alan Kawarai Lefor, Sawako Tamaki, Akinari Takao, Misato Takao, Yoshiko Mori, Kenichi Chikatani, Hideyuki Ishida, Mitsuhiro Kono, Yoji Takeuchi, Hideki Ishikawa, Toshiya Nagasaki, Kazuhito Sasaki, Takaaki Matsubara, Keiji Hirata, Fumitaka Taniguchi, Kohji Tanakaya, Naohiro Tomita, Yoichi Ajioka
Management of duodenal or ampullary adenomas in patients with familial adenomatous polyposis (FAP) is a major challenge for clinicians. Insufficient data are available to evaluate the clinical manifestations and distribution of adenomatous polyposis coli (APC) variants in these patients. We enrolled 451 patients with data regarding duodenal or ampullary polyps from 632 patients with FAP retrospect...... hiện toàn bộ
Testicular dermoid cyst in an 85-year-old man
International Journal of Clinical Oncology - Tập 5 Số 2 - Trang 144-145 - 2000
Nakata, S., Morita, T., Higashi, H., Takahashi, H., Shimizu, K.
We report a case of dermoid cyst of the right testis. An 85-year-old man was admitted to our hospital with an enlarged right testicle and a high prostate specific antigen (PSA) level. A hard testis of approximately 10 cm, with a smooth surface, was palpated. On digital rectal examination, a hard prostate of approximately 4 cm, with irregular surface, was palpated. We performed right inguinal orchi...... hiện toàn bộ
Salvage chemotherapy for recurrent or persistent clear cell carcinoma of the ovary: a single-institution experience for a series of 20 patients
International Journal of Clinical Oncology - Tập 18 - Trang 148-153 - 2011
Kiyoshi Yoshino, Takayuki Enomoto, Masami Fujita, Yutaka Ueda, Toshihiro Kimura, Eiji Kobayashi, Tateki Tsutsui, Tadashi Kimura
Recurrent or persistent clear cell carcinoma (CCC) of the ovary is particularly chemotherapy resistant. The purpose of this study was to review our extensive institutional experiences with recurrent or persistent CCC with the aim of finding a more effective chemotherapy regimen. The medical records of 67 patients treated for CCC of the ovary were retrospectively reviewed to select patients subsequ...... hiện toàn bộ
Treatment outcomes and dose-volume histogram analysis of simultaneous integrated boost method for malignant gliomas using intensity-modulated radiotherapy
International Journal of Clinical Oncology - Tập 13 - Trang 48-53 - 2008
Kiyoshi Nakamatsu, Minoru Suzuki, Yasumasa Nishimura, Shuichi Kanamori, Ryuta Koike, Toru Shibata, Naoya Shintani, Masahiko Okumura, Kaoru Okajima, Fumiharu Akai
The aim of this article is to report the treatment outcomes, toxicities, and dosimetric feasibility of our simultaneous-boost intensity-modulated radiotherapy (SIB-IMRT) protocol. Thirteen patients with malignant gliomas treated between December 2000 and September 2004 were enrolled in this study. Two planning target volumes (PTVs) were defined in the present study. Our IMRT regimen delivered 70 G...... hiện toàn bộ
Palbociclib in combination with fulvestrant in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: PALOMA-3 subgroup analysis of Japanese patients
International Journal of Clinical Oncology - - 2018
Norikazu Masuda, Kenichi Inoue, Rikiya Nakamura, Yoshiaki Rai, Hirofumi Mukai, Shinji Ohno, Fumikata Hara, Yuko Mori, Satoshi Hashigaki, Yasuaki Muramatsu, Takashi Nagasawa, Yoshiko Umeyama, Xin Huang, Hiroji Iwata
In the double-blind, phase 3 PALOMA-3 study, palbociclib–fulvestrant significantly prolonged progression-free survival versus placebo–fulvestrant in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2–) metastatic breast cancer (MBC) whose disease had progressed on prior endocrine therapy. The present study evaluated the efficacy, safety, and phar...... hiện toàn bộ
Risk factors for metachronous colorectal cancer in Lynch syndrome patients: a registry-based observational mono-institutional study cohort
International Journal of Clinical Oncology - Tập 25 Số 9 - Trang 1644-1652 - 2020
Stefano Signoroni, Guglielmo Niccolò Piozzi, Maria Teresa Ricci, Andrea Mancini, Alberto Morabito, Lucio Bertario, Marco Vitellaro
Comparison of survival outcomes between adolescent and young adults and older adults with tongue squamous cell carcinoma: a nationwide database study using the head and neck cancer registry of Japan
International Journal of Clinical Oncology - Tập 28 - Trang 221-228 - 2022
Go Omura, Seiichi Yoshimoto, Ryoko Rikitake, Kohtaro Eguchi, Munenaga Nakamizo, Ken-ichi Nibu
This study aimed to evaluate the prognostic outcome for adolescent and young adult (AYA) generation patients with tongue squamous cell carcinoma (TSCC). Data were obtained from the Head and Neck Cancer Registry of Japan, and patients who were newly diagnosed with TSCC from 2011 to 2014 were extracted. We compared the clinical parameter and survival of the ≤ 39 years old (AYA) patient group with th...... hiện toàn bộ
Pulmonary metastasectomy in patients with renal cell carcinoma: a single-institution experience
International Journal of Clinical Oncology - Tập 16 - Trang 660-665 - 2011
Atsunari Kawashima, Masashi Nakayama, Daizo Oka, Mototaka Sato, Koji Hatano, Masatoshi Mukai, Akira Nagahara, Yasutomo Nakai, Hitoshi Takayama, Masayoshi Inoue, Hiroyuki Shiono, Kazuo Nishimura, Meinoshin Okumura, Norio Nonomura
Pulmonary metastasectomy in patients with renal cell carcinoma (RCC) remains controversial. The purpose of our analysis was to explore the outcome of patients with RCC who underwent pulmonary metastasectomy at our institution. We reviewed data on 25 patients who underwent resection of lung metastasis from 1998 to 2008 at our institution. All patients were treated by radical nephrectomy for primary...... hiện toàn bộ
A retrospective study of urokinase-type plasminogen activator receptor (uPAR) as a prognostic factor in cancer of the uterine cervix
International Journal of Clinical Oncology - - 2014
Toru Sasaki, Hirotaka Nishi, Chie Nagata, Takeshi Nagai, Toshitaka Nagao, Fumitoshi Terauchi, Keiichi Isaka
Hypoxia occurs during the development of uterine cervical cancer and is considered to correlate with its invasion. Hypoxia promotes both the invasiveness and the metastasis of cancer cells through urokinase-type plasminogen activator receptor (uPAR) expression. The aim of this study was to evaluate the correlation between uPAR mRNA level and clinical prognostic factors of uterine cervical cancer. ...... hiện toàn bộ
Growing teratoma syndrome of ovary
International Journal of Clinical Oncology - Tập 13 - Trang 83-87 - 2008
Roopa Hariprasad, Lalit Kumar, Deepa Janga, Sunesh Kumar, Malini Vijayaraghavan
Growing teratoma syndrome is an increase of tumor size containing only a mature teratoma component, during or after chemotherapy for germ cell tumors. Mature teratomatous elements are chemoresistant and have to be resected surgically. We describe three patients with malignant immature teratoma treated with chemotherapy and surgical resection. All three had an increase in the size of the mass after...... hiện toàn bộ
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