International Journal of Breast Cancer
ESCI-ISI SCOPUS (2013-2024)
2090-3170
2090-3189
Ai cập
Cơ quản chủ quản: Hindawi Limited , HINDAWI LTD
Lĩnh vực:
OncologyCancer ResearchPharmacology (medical)
Các bài báo tiêu biểu
Drug Resistance and the Role of Combination Chemotherapy in Improving Patient Outcomes
Tập 2013 - Trang 1-15 - 2013
Resistance to cancer chemotherapy is a common phenomenon especially in
metastatic breast cancer (MBC), a setting in which patients typically have had
exposure to multiple lines of prior therapy. The subsequent development of drug
resistance can result in rapid disease progression during or shortly after
completion of treatment. Moreover, cross-class multidrug resistance limits
patient treatment ch...
Evaluation of Antiproliferative Activity of Red Sorghum Bran Anthocyanin on a Human Breast Cancer Cell Line (MCF-7)
Tập 2011 - Trang 1-6 - 2011
Breast cancer is a leading cause of death in women worldwide both in the
developed and developing countries. Thus effective treatment of breast cancer
with potential antitumour drugs is important. In this paper, human breast cancer
cell line MCF-7 has been employed to evaluate the antiproliferative activity of
red sorghum bran anthocyanin. The present investigation showed that red sorghum
bran ant...
Metronomic Cyclophosphamide and Methotrexate Chemotherapy Combined with 1E10 Anti-Idiotype Vaccine in Metastatic Breast Cancer
Tập 2011 - Trang 1-6 - 2011
The use of low doses of cytotoxic agents continuously for prolonged periods is
an alternative for the treatment of patients with metastatic breast cancer who
have developed resistance to conventional chemotherapy. The combination of
metronomic chemotherapy with therapeutic vaccines might increase the efficacy of
the treatment. Twenty one patients with metastatic breast cancer in progression
and a ...
Utilization of Oncotype DX in an Inner City Population: Race or Place?
Tập 2013 - Trang 1-3 - 2013
Oncotype DX, a 21-gene-array analysis, can guide chemotherapy treatment
decisions for women with ER+ tumors. Of 225 ER+ women participating in a patient
assistance trial, 23% underwent Oncotype DX testing: 31% of whites, 21% of
blacks, and 14% of Hispanics (P=0.04) were tested. Only 3 white women were
treated at municipal hospitals and none was tested. 3% of women treated in
municipal hospital as ...
Target Points in Trastuzumab Resistance
Tập 2012 - Trang 1-9 - 2012
Epidermal growth factor (EGF) family of receptors is involved in cell growth and
differentiation. The human EGF2 (HER2) lacks natural ligands, and correlation
between HER2 levels and carcinogenesis makes the receptor an ideal candidate for
targeted therapy in breast cancer. Trastuzumab is a humanized antibody applied
against HER2-positive breast tumors in clinic. Metastatic tumors respond well to
...