International Archives of Allergy and Immunology

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Histamine Release from Human Leukocytes by Platelet-Activating Factor
International Archives of Allergy and Immunology - Tập 85 Số 3 - Trang 341-345 - 1988
Yasuhisa Okuda, I Tsuyuguchi, Atsushi Yamatodani
Platelet-activating factor (PAF) was found to induce histamine release from human basophils in mixed leukocytes in the presence of cytochalasin B. The reaction was rapid and dependent on temperature. The release was lower at a high concentration of PAF and was inhibited by EDTA, suggesting a noncytolytic mechanism. CV-3988, a PAF antagonist, inhibited the reaction dose-dependently. PAF act...... hiện toàn bộ
In vitro Effects of 13-Cis-Retinoic Acid (Ro 4-3780) and Etretinate (Ro 10-9359) on DNA Synthesis and Fine Structure of Guinea Pig and Human Lymphoid Cells
International Archives of Allergy and Immunology - Tập 71 Số 4 - Trang 363-367 - 1983
K. Nordlind, Johan Thyberg
In vitro effects of the retinoids 13-cis-retinoic acid (Ro4-3780) and etretinate (Ro 10-9359) on DNA synthesis and the fine structure of different guinea pig and human lymphoid cells were tested. 13-Cis-retinoic acid caused a dose-dependent inhibition of DNA synthesis most prominently in thymocytes. This effect was not due to an inhibition of thymidine uptake into the cells. Electron micro...... hiện toàn bộ
Bronchus-Associated Lymphoid Tissue
International Archives of Allergy and Immunology - Tập 76 Số Suppl. 1 - Trang 62-69 - 1985
John Bienenstock
Characteristics and Immunobiology of Grass Pollen Allergens
International Archives of Allergy and Immunology - Tập 130 Số 2 - Trang 87-107 - 2003
Kerstin Andersson, Jonas Lidholm
Grass pollens are one of the most important airborne allergen sources worldwide. About 20 species from five subfamilies are considered to be the most frequent causes of grass pollen allergy, and the allergenic relationships among them closely follow their phylogenetic relationships. The allergic immune response to pollen of several grass species has been studied extensively over more than ...... hiện toàn bộ
Carbohydrate Epitopes and Their Relevance for the Diagnosis and Treatment of Allergic Diseases
International Archives of Allergy and Immunology - Tập 129 Số 3 - Trang 189-197 - 2002
Ronald van Ree
Allergenicity of plant and invertebrate N-glycans has been shown to be caused by the presence of two typical nonmammalian substitutions: an α(1,3)-fucose linked to the proximal N-acetylglucosamine and a β(1,2)-xylose linked to the core mannose. IgE antibodies against these carbohydrate structures are induced upon exposure to pollen or after insect stings, and result in extensive cross-reac...... hiện toàn bộ
IgE to Cross-Reactive Carbohydrate Determinants: Analysis of the Distribution and Appraisal of the in vivo and in vitro Reactivity
International Archives of Allergy and Immunology - Tập 129 Số 4 - Trang 286-295 - 2002
Adriano Mari
<i>Background:</i> IgE to cross-reacting carbohydrate determinants has already been described by several authors, but their function and distribution are still a matter of debate. In previous studies we showed how the presence of IgE to bromelain could be a useful and simple marker of the presence of IgE to carbohydrate epitopes. <i>Methods:</i> A survey of 1,831 su...... hiện toàn bộ
Usefulness and Limitations of Sequential Serum Tryptase for the Diagnosis of Anaphylaxis in 102 Patients
International Archives of Allergy and Immunology - Tập 160 Số 2 - Trang 192-199 - 2013
Anna Sala, Victória Cardona, Moisés Labrador‐Horrillo, Olga Luengo, Olga Esteso, Teresa Garriga, María Vicario, Mar Guilarte
Background: The diagnosis of anaphylaxis is based on clinical history since no reliable biological marker is currently available to confirm the diagnosis. Objective: It was the aim of this study to determine sequential serum tryptase concentrations during anaphylaxis and to evaluate its potential as a diagnostic marker. Methods: We performed a prospective study including patients with acut...... hiện toàn bộ
Antibodies against Polyethylene Glycol Produced in Animals by Immunization with Monomethoxy Polyethylene Glycol Modified Proteins
International Archives of Allergy and Immunology - Tập 70 Số 2 - Trang 124-131 - 1983
Ary Wolfgang Richter, Eva Åkerblom
Antibodies to polyethylene glycol (PEG) were raised in rabbits by immunization with monomethoxy polyethylene glycol modified ovalbumin (OA), bovine superoxide dismutase (SOD), and ragweed pollen extract (Rag), given in Freund’s complete adjuvant (FCA). Immunogenicity depended on the nature of the protein and the degree of modification. With modified OA, in the presence of FCA, the majority...... hiện toàn bộ
Novel Treatments for Drug-Induced Toxic Epidermal Necrolysis (Lyell’s Syndrome)
International Archives of Allergy and Immunology - Tập 136 Số 3 - Trang 205-216 - 2005
Philippe Paquet, Gérald Pierard, Pascale Quatresooz
Drug-induced toxic epidermal necrolysis (TEN) is a life-threatening disease characterized by extensive destruction of the epidermis. It apparently results from the formation of specific toxic drug metabolites by the keratinocytes. The mortality rate which averages 25–30% is mainly due to secondary septicemia, and to ionic and metabolic disturbances following loss of epidermal integrity. Ap...... hiện toàn bộ
Comparison of Conidial and Mycelial Allergens of <i>Alternaria alternata</i>
International Archives of Allergy and Immunology - Tập 92 Số 1 - Trang 1-8 - 1990
Sophie Paris, Catherine Fitting, Jean‐Paul Latgé, Dale E. Herman, M.T. Guinnepain, Brinda G. David
<i>Alternaria allergens</i>, separated by SDS polyacrylamide gel electrophoresis and transferred onto a nitrocellulose membrane, were identified using sera from <i>Alternaria</i>-allergic patients. 30 <i>Alternaria</i> components of spore and mycelium, ranging in molecular weight from more than 150 to 12 kD, bound IgE antibodies. 15 were detected by more...... hiện toàn bộ
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