Histamine Release from Human Leukocytes by Platelet-Activating FactorInternational Archives of Allergy and Immunology - Tập 85 Số 3 - Trang 341-345 - 1988
Yasuhisa Okuda, I Tsuyuguchi, Atsushi Yamatodani
Platelet-activating factor (PAF) was found to induce histamine release from human basophils in mixed leukocytes in the presence of cytochalasin B. The reaction was rapid and dependent on temperature. The release was lower at a high concentration of PAF and was inhibited by EDTA, suggesting a noncytolytic mechanism. CV-3988, a PAF antagonist, inhibited the reaction dose-dependently. PAF act...... hiện toàn bộ
Carbohydrate Epitopes and Their Relevance for the Diagnosis and Treatment of Allergic DiseasesInternational Archives of Allergy and Immunology - Tập 129 Số 3 - Trang 189-197 - 2002
Ronald van Ree
Allergenicity of plant and invertebrate N-glycans has been shown to be caused by the presence of two typical nonmammalian substitutions: an α(1,3)-fucose linked to the proximal N-acetylglucosamine and a β(1,2)-xylose linked to the core mannose. IgE antibodies against these carbohydrate structures are induced upon exposure to pollen or after insect stings, and result in extensive cross-reac...... hiện toàn bộ
Usefulness and Limitations of Sequential Serum Tryptase for the Diagnosis of Anaphylaxis in 102 PatientsInternational Archives of Allergy and Immunology - Tập 160 Số 2 - Trang 192-199 - 2013
Anna Sala, Victória Cardona, Moisés Labrador‐Horrillo, Olga Luengo, Olga Esteso, Teresa Garriga, María Vicario, Mar Guilarte
Background: The diagnosis of anaphylaxis is based on clinical history since no reliable biological marker is currently available to confirm the diagnosis. Objective: It was the aim of this study to determine sequential serum tryptase concentrations during anaphylaxis and to evaluate its potential as a diagnostic marker. Methods: We performed a prospective study including patients with acut...... hiện toàn bộ
Antibodies against Polyethylene Glycol Produced in Animals by Immunization with Monomethoxy Polyethylene Glycol Modified ProteinsInternational Archives of Allergy and Immunology - Tập 70 Số 2 - Trang 124-131 - 1983
Ary Wolfgang Richter, Eva Åkerblom
Antibodies to polyethylene glycol (PEG) were raised in rabbits by immunization with monomethoxy polyethylene glycol modified ovalbumin (OA), bovine superoxide dismutase (SOD), and ragweed pollen extract (Rag), given in Freund’s complete adjuvant (FCA). Immunogenicity depended on the nature of the protein and the degree of modification. With modified OA, in the presence of FCA, the majority...... hiện toàn bộ
Novel Treatments for Drug-Induced Toxic Epidermal Necrolysis (Lyell’s Syndrome)International Archives of Allergy and Immunology - Tập 136 Số 3 - Trang 205-216 - 2005
Philippe Paquet, Gérald Pierard, Pascale Quatresooz
Drug-induced toxic epidermal necrolysis (TEN) is a life-threatening disease characterized by extensive destruction of the epidermis. It apparently results from the formation of specific toxic drug metabolites by the keratinocytes. The mortality rate which averages 25–30% is mainly due to secondary septicemia, and to ionic and metabolic disturbances following loss of epidermal integrity. Ap...... hiện toàn bộ
Standardization of Allergenic Extracts of <i>Aspergillus fumigatus</i>International Archives of Allergy and Immunology - Tập 76 Số 2 - Trang 168-173 - 1985
H.F. Kauffman, S. van der Heide, Siem van der Laan, H. Hovenga, F Beaumont, K. de Vries
During cultivation of <i>Aspergillus fumigatus </i>a rapid liberation of IgE-binding components was found reaching maximum values during the logarithmic phase of growth (phase I). After a fall in IgE-binding titers during phase II, appearance of additional IgE-binding components was noted during the period of lysis of the microorganism (phase III). These latter allergenic compo...... hiện toàn bộ
Partial Purification and Characterization of Two <i>Cladosporium herbarum </i>AllergensInternational Archives of Allergy and Immunology - Tập 60 Số 1 - Trang 68-79 - 1979
L. Aukrust, S. M. Borch
Two important <i>Cladosporium herbarum </i>allergens (Ag-54 and Ag-32) were partly purified by means of diafiltration, gel filtration and isoelectric focusing. Modifications of quantitative immunological techniques, including autoradiography, were used as assay systems for allergenic activity and to provide a basis for evaluation of the immunological purity of the allergens. Ag...... hiện toàn bộ