Inflammopharmacology

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Anti-inflammatory and analgesic actions of etoricoxib (an NSAID) combined with misoprostol
Inflammopharmacology - - 2007
B. Medeiros Moraes, Brenda Amaral, Michio Morimoto, L. G. Cardoso Vieira, Fábio Ferreira Perazzo, José Carlos Tavares Carvalho
Covid-19: pharmacotherapeutic insights on various curative approaches in terms of vulnerability, comorbidities, and vaccination
Inflammopharmacology - Tập 30 Số 1 - Trang 1-21 - 2022
Rupinder Kaur, Simranjeet Singh, Thakur Gurjeet Singh, Pragati Sood, J Desnick Robert
Differential inhibition of cyclooxygenase-1 (COX-1) and-2 (COX-2) by NSAIDS: Consequences on anti-inflammatory activity versus gastric and renal safety
Inflammopharmacology - Tập 4 - Trang 61-70 - 1996
M. Pairet, L. Churchill, G. Trummlitz, G. Engelhardt
The discovery of an inducible isoform of cyclooxygenase (COX-2) requires a refinement of the theory that inhibition of cyclooxygenase activity is responsible for both therapeutic and side-effects of nonsteroidal anti-inflammatory drugs (NSAIDs). Pharmacological results with developmental compounds suggest that COX-2 is the relevant target for the therapeutic (i.e. anti-inflammatory) effects of NSA...... hiện toàn bộ
Protective effects of lysozyme chloride and reduced glutathione on betel quid chewing-produced gastric oxidative stress and haemorrhagic ulcer in rats
Inflammopharmacology - Tập 12 - Trang 115-129 - 2004
Chen-Road Hung
The pathogenic mechanisms underlying betel quid chewing (BQC)-induced gastric haemorrhagic ulcer are totally unknown. This study first demonstrated that BQC produced gastric haemorrhagic ulcer via oxidative stress that could be protected by lysozyme chloride and glutathione in rats. Male Wistar rats were fed with regular pellet food or BQC-containing diets. After 1–90 days rats were deprived of fo...... hiện toàn bộ
Losartan suppresses the inflammatory response in collagen-induced arthritis by inhibiting the MAPK and NF-κB pathways in B and T cells
Inflammopharmacology - Tập 27 - Trang 487-502 - 2018
Xinming Wang, Xiaoyun Chen, Wei Huang, Pengying Zhang, Yawei Guo, Heinrich Körner, Huaxun Wu, Wei Wei
The angiotensin II type 1 receptor (AT1R) antagonist losartan has been confirmed to have a moderate anti-inflammatory effect in vitro and in vivo. However, how it affects immune cells in Rheumatoid Arthritis (RA) is still unknown. We found that in human synovial tissues, AT1R is significantly expressed on T cells and B cells. Treatment with losartan (15 mg/kg) alone and in combination with a low d...... hiện toàn bộ
The involvement of H2 receptor number on the regulation of histamine-mediated cell growth
Inflammopharmacology - Tập 8 - Trang 243-258 - 2000
Carlos Patricio Fitzsimons
Histamine has been implicated in the control of cell growth of diverse tissues and cell lines. The effect of histamine is mediated by the interaction with its specific receptors, which belong to the family of seven transmembrane G-protein-coupled receptors (GPCRs). However, the mechanism(s) involved and the factors that regulate this process have not yet been determined. In this article the releva...... hiện toàn bộ
Experimental antral ulcer and several protective drugs
Inflammopharmacology - Tập 10 - Trang 375-384 - 2002
C. R. Hung
Antral ulcer may result from infection of Helicobacter pylori, duodenal bile reflux or gastritis. Several animal antral ulcer models were used to evaluate protection of drugs. Chemicals used to induce antral ulcer were diethyldithiocarbamate, indomethacin and strong acid solutions. Because these treatments produce damage of gastrointestinal tissues other than the antrum, most of these ulcer models...... hiện toàn bộ
Evaluation of the efficacy of Thymus kotschyanus extract as an additive treatment in patients with ulcerative colitis: a randomized double-blind placebo-controlled trial
Inflammopharmacology - Tập 30 Số 6 - Trang 2145-2152 - 2022
Fatemeh Vazirian, Sara Samadi, Mohammadreza Abbaspour, Amirmahdi Taleb, Hadi Bagherhosseini, Hooman Mosannen Mozaffari, Amir Hooshang Mohammadpour, Seyed Ahmad Emami
SIRT1 pathway in Parkinson’s disease: a faraway snapshot but so close
Inflammopharmacology - Tập 31 Số 1 - Trang 37-56 - 2023
Gaber El‐Saber Batiha, Hayder M Al-Kuraishy, Ali I. Al‐Gareeb, Engy Elekhnawy
AbstractSilent information regulator (SIRT) has distinctive enzymatic activities and physiological functions to control cell-cycle progression, gene expression, and DNA stability by targeting histone and non-histone proteins. SIRT1 enhances synaptic formation and synaptic activity, and therefore, can reduce the progression of various degenerative brain diseases inc...... hiện toàn bộ
The effects of melatonin supplementation on inflammatory markers among patients with metabolic syndrome or related disorders: a systematic review and meta-analysis of randomized controlled trials
Inflammopharmacology - Tập 26 Số 4 - Trang 899-907 - 2018
Maryam Akbari, Vahidreza Ostadmohammadi, Reza Tabrizi, Kamran Bagheri Lankarani, Mohammad Heydari, Elaheh Amirani, Rüssel J. Reiter, Zatollah Asemi
Tổng số: 1,443   
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