Arnett FC et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315–324
Bernstein KE, Khan Z, Giani JF, Cao DY, Bernstein EA, Shen XZ (2018) Angiotensin-converting enzyme in innate and adaptive immunity Nature reviews. Nephrology 14:325–336. https://doi.org/10.1038/nrneph.2018.15
Bird HA et al (1990) A clinical and biochemical assessment of a nonthiol ACE inhibitor (pentopril; CGS-13945) in active rheumatoid arthritis. J Rheumatol 17:603–608
Cao XP et al (2016) Hepatocyte growth factor enhances the inflammation-alleviating effect of umbilical cord-derived mesenchymal stromal cells in a bronchiolitis obliterans model. Cytotherapy 18:402–412. https://doi.org/10.1016/j.jcyt.2015.12.006
Chan CT et al (2015) Obligatory role for B cells in the development of angiotensin II-dependent hypertension. Hypertension 66:1023–1033. https://doi.org/10.1161/HYPERTENSIONAHA.115.05779
Chang CA, Murphy K, Kane RR, Lawrence M, Naziruddin B (2018) Early TLR4 blockade attenuates sterile inflammation-mediated stress in islets during isolation and promotes successful transplant outcomes. Transplantation. https://doi.org/10.1097/tp.0000000000002287
Cheng ZJ, Vapaatalo H, Mervaala E (2005) Angiotensin II and vascular inflammation. Med Sci Monitor Int Med J Exp Clin Res 11:RA194–RA205
Cohen S et al (2001) Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate Utilization of Leflunomide in the Treatment of Rheumatoid Arthritis Trial Investigator Group. Arthritis Rheum 44:1984–1992. https://doi.org/10.1002/1529-0131(200109)44:9%3c1984:aid-art346%3e3.0.co;2-b
Feldmann M et al (2002) Is NF-kappaB a useful therapeutic target in rheumatoid arthritis? Ann Rheum Dis 61(Suppl 2):ii13–ii18
Firestein GS, McInnes IB (2017) Immunopathogenesis of rheumatoid arthritis immunity 46:183–196. https://doi.org/10.1016/j.immuni.2017.02.006
Goldszmid RS et al (2012) NK cell-derived interferon-gamma orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection. Immunity 36:1047–1059. https://doi.org/10.1016/j.immuni.2012.03.026
Haleagrahara N, Hodgson K, Miranda-Hernandez S, Hughes S, Kulur AB, Ketheesan N (2018) Flavonoid quercetin-methotrexate combination inhibits inflammatory mediators and matrix metalloproteinase expression, providing protection to joints in collagen-induced arthritis. Inflammopharmacology. https://doi.org/10.1007/s10787-018-0464-2
Hoch NE et al (2009) Regulation of T-cell function by endogenously produced angiotensin II American journal of physiology. Regul Integr Compar Physiol 296:R208–R216. https://doi.org/10.1152/ajpregu.90521.2008
Huang L et al (2018) OX40L induces helper T cell differentiation during cell immunity of asthma through PI3K/AKT and P38 MAPK signaling pathway. Journal of translational medicine 16:74. https://doi.org/10.1186/s12967-018-1436-4
Husain K, Hernandez W, Ansari RA, Ferder L (2015) Inflammation, oxidative stress and renin angiotensin system in atherosclerosis. World J Biol Chem 6:209–217. https://doi.org/10.4331/wjbc.v6.i3.209
Jia Y, Miao Y, Yue M, Shu M, Wei Z, Dai Y (2018) Tetrandrine attenuates the bone erosion in collagen-induced arthritis rats by inhibiting osteoclastogenesis via spleen tyrosine kinase. FASEB J 32:3398–3410. https://doi.org/10.1096/fj.201701148RR
Jones DS, Jenney AP, Joughin BA, Sorger PK, Lauffenburger DA (2018) Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition. Science Signal. https://doi.org/10.1126/scisignal.aal1601
Kondo Y et al (2018) Review: Transcriptional regulation of CD4 + T cell differentiation in experimentally induced arthritis and rheumatoid arthritis. Arthritis Rheumatol 70:653–661. https://doi.org/10.1002/art.40398
Kvakan H et al (2009) Regulatory T cells ameliorate angiotensin II-induced cardiac damage. Circulation 119:2904–2912. https://doi.org/10.1161/CIRCULATIONAHA.108.832782
LaMarca B, Wallace K, Herse F, Wallukat G, Martin JN Jr, Weimer A, Dechend R (2011) Hypertension in response to placental ischemia during pregnancy: role of B lymphocytes. Hypertension 57:865–871. https://doi.org/10.1161/HYPERTENSIONAHA.110.167569
Latha RM, Geetha T, Varalakshmi P (1998) Effect of Vernonia cinerea Less flower extract in adjuvant-induced arthritis. General Pharmacol 31:601–606
Li JM et al (2018) Vanillin-ameliorated development of azoxymethane/dextran sodium sulfate-induced murine colorectal cancer: the involvement of proteasome/nuclear factor-kappaB/mitogen-activated protein kinase pathways. J Agric Food Chem. https://doi.org/10.1021/acs.jafc.8b01582
Liu Z, Li B, Li X, Zhang L, Lai L (2011) Identification of small-molecule inhibitors against human leukocyte antigen-death receptor 4 (HLA-DR4) through a comprehensive strategy. J Chem Inf Model 51:326–334. https://doi.org/10.1021/ci100444c
MacKenzie A (2011) Endothelium-derived vasoactive agents, AT1 receptors and inflammation. Pharmacol Ther 131:187–203. https://doi.org/10.1016/j.pharmthera.2010.11.001
Makarov SS (2001) NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction. Arthritis Res 3:200–206. https://doi.org/10.1186/ar300
Martin MF, Surrall KE, McKenna F, Dixon JS, Bird HA, Wright V (1984) Captopril: a new treatment for rheumatoid arthritis? Lancet 1:1325–1328
Mellado M, Martinez-Munoz L, Cascio G, Lucas P, Pablos JL, Rodriguez-Frade JM (2015) T cell migration in rheumatoid arthritis. Front Immunol 6:384. https://doi.org/10.3389/fimmu.2015.00384
Muller DN et al (2002) Immunosuppressive treatment protects against angiotensin II-induced renal damage. Am J Pathol 161:1679–1693. https://doi.org/10.1016/S0002-9440(10)64445-8
Nabbi A, Riabowol K (2015) Rapid isolation of nuclei from cells in vitro. Cold Spring Harbor Protoc 2015:769–772. https://doi.org/10.1101/pdb.prot083733
Ohkura Y et al (2015) Primary adrenal lymphoma possibly associated with Epstein–Barr virus reactivation due to immunosuppression under methotrexate therapy. Medicine 94:e1270. https://doi.org/10.1097/MD.0000000000001270
Onuora S (2016) Rheumatoid arthritis: vagus nerve stimulation reduces RA severity in patients Nature reviews. Rheumatology 12:500. https://doi.org/10.1038/nrrheum.2016.126
Pala O, Diaz A, Blomberg BB, Frasca D (2018) B lymphocytes in rheumatoid arthritis and the effects of anti-TNF-alpha agents on B lymphocytes: a review of the literature. Clin Ther 6:7. https://doi.org/10.1016/j.clinthera.2018.04.016
Perry ME, Chee MM, Ferrell WR, Lockhart JC, Sturrock RD (2008) Angiotensin receptor blockers reduce erythrocyte sedimentation rate levels in patients with rheumatoid arthritis. Ann Rheum Dis 67:1646–1647. https://doi.org/10.1136/ard.2007.082917
Price A, Lockhart JC, Ferrell WR, Gsell W, McLean S, Sturrock RD (2007) Angiotensin II type 1 receptor as a novel therapeutic target in rheumatoid arthritis: in vivo analyses in rodent models of arthritis and ex vivo analyses in human inflammatory synovitis. Arthritis Rheum 56:441–447. https://doi.org/10.1002/art.22335
Queiroz-Junior CM et al (2015) Protective effects of the angiotensin type 1 receptor antagonist losartan in infection-induced and arthritis-associated alveolar bone loss. J Periodontal Res 50:814–823. https://doi.org/10.1111/jre.12269
Refaat R, Salama M, Abdel Meguid E, El Sarha A, Gowayed M (2013) Evaluation of the effect of Losartan and methotrexate combined therapy in adjuvant-induced arthritis in rats. Eur J Pharmacol 698:421–428. https://doi.org/10.1016/j.ejphar.2012.10.024
Renna NF, Lembo C, Diez E, Miatello RM (2013) Role of Renin–Angiotensin system and oxidative stress on vascular inflammation in insulin resistance model. Int J Hypertens 2013:420979. https://doi.org/10.1155/2013/420979
Sagawa K, Nagatani K, Komagata Y, Yamamoto K (2005) Angiotensin receptor blockers suppress antigen-specific T cell responses and ameliorate collagen-induced arthritis in mice. Arthritis Rheum 52:1920–1928. https://doi.org/10.1002/art.21040
Salinas GF, Braza F, Brouard S, Tak PP, Baeten D (2013) The role of B lymphocytes in the progression from autoimmunity to autoimmune disease Clinical immunology 146:34–45. https://doi.org/10.1016/j.clim.2012.10.005
Shao J, Nangaku M, Miyata T, Inagi R, Yamada K, Kurokawa K, Fujita T (2003) Imbalance of T-cell subsets in angiotensin II-infused hypertensive rats with kidney injury. Hypertension 42:31–38. https://doi.org/10.1161/01.HYP.0000075082.06183.4E
Silveira KD et al (2013) Mechanisms of the anti-inflammatory actions of the angiotensin type 1 receptor antagonist Losartan in experimental models of arthritis. Peptides 46:53–63. https://doi.org/10.1016/j.peptides.2013.05.012
Smolen JS, Aletaha D (2015) Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges. Nat Rev Rheumatol 11:276–289. https://doi.org/10.1038/nrrheum.2015.8
Sun W et al (2018) Sam68 promotes invasion, migration, and proliferation of fibroblast-like synoviocytes by enhancing the NF-kappaB/P65 pathway in rheumatoid arthritis. Inflammation 6:7. https://doi.org/10.1007/s10753-018-0809-4
Walsh DA, Suzuki T, Knock GA, Blake DR, Polak JM, Wharton J (1994) AT1 receptor characteristics of angiotensin analogue binding in human synovium. Br J Pharmacol 112:435–442
Wang D et al (2013) Angiotensin II type 2 receptor correlates with therapeutic effects of Losartan in rats with adjuvant-induced arthritis. J Cell Mol Med 17:1577–1587. https://doi.org/10.1111/jcmm.12128
Wang Q et al (2017) Paroxetine alleviates T lymphocyte activation and infiltration to joints of collagen-induced arthritis. Sci Rep 7:45364. https://doi.org/10.1038/srep45364
Wu H et al (2018) beta2-adrenoceptor signaling reduction is involved in the inflammatory response of fibroblast-like synoviocytes from adjuvant-induced arthritic rats. Inflammopharmacology 6:7. https://doi.org/10.1007/s10787-018-0477-x
Xu M, Liu S, Wan R, Chen Y (2018) Combined treatment with sinomenine and acupuncture on collagen-induced arthritis through the NF-kappaB and MAPK signaling pathway. Oncol Lett 15:8770–8776. https://doi.org/10.3892/ol.2018.8394
Yang G, Li S, Yuan L, Yang Y, Pan MH (2017) Effect of nobiletin on the MAPK/NF-kappaB signaling pathway in the synovial membrane of rats with arthritis induced by collagen. Food Funct 8:4668–4674. https://doi.org/10.1039/c7fo01311f
Yao Y, Liu K, Zhao Y, Hu X, Wang M (2018) Pterostilbene and 4′-methoxyresveratrol inhibited lipopolysaccharide-induced inflammatory response in RAW264.7 Macrophages. Molecules 23:7. https://doi.org/10.3390/molecules23051148
Zaringhalam J, Akhtari Z, Eidi A, Ruhani AH, Tekieh E (2014) Relationship between serum IL10 level and p38MAPK enzyme activity on behavioral and cellular aspects of variation of hyperalgesia during different stages of arthritis in rats. Inflammopharmacology 22:37–44. https://doi.org/10.1007/s10787-013-0174-8
Zeng L, Li L, Zeng Q, Deng Y, Yin L, Liao L (2018) Mitogenic activity of Artocarpus lingnanensis lectin and its apoptosis induction in Jurkat T cells. J Nat Med 72:745–756. https://doi.org/10.1007/s11418-018-1212-z
Zhai KF, Duan H, Luo L, Cao WG, Han FK, Shan LL, Fang XM (2017) Protective effects of paeonol on inflammatory response in IL-1beta-induced human fibroblast-like synoviocytes and rheumatoid arthritis progression via modulating NF-kappaB pathway. Inflammopharmacology 6:7. https://doi.org/10.1007/s10787-017-0385-5
Zhang F et al (2017a) CP-25, a Novel Anti-inflammatory and Immunomodulatory Drug, Inhibits the Functions of Activated Human B Cells through Regulating BAFF and TNF-alpha Signaling and Comparative Efficacy with Biological Agents. Front Pharmacol 8:933. https://doi.org/10.3389/fphar.2017.00933
Zhang ZH et al (2017b) Total glucosides of paeony inhibits lipopolysaccharide-induced proliferation, migration and invasion in androgen insensitive prostate cancer cells. PLoS One 12:e0182584. https://doi.org/10.1371/journal.pone.0182584
Zhu J, Paul WE (2010) Peripheral CD4 + T-cell differentiation regulated by networks of cytokines and transcription factors. Immunol Rev 238:247–262. https://doi.org/10.1111/j.1600-065x.2010.00951.x