In vitro models
ESCI-ISI
2731-3441
Cơ quản chủ quản: N/A
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Các bài báo tiêu biểu
Application of a 3D hydrogel-based model to replace use of animals for passaging patient-derived xenografts Abstract
Purpose
This 3D in vitro cancer model for propagation of patient-derived cells, using a synthetic self-assembling peptide gel, allows the formation of a fully characterised, tailorable tumour microenvironment. Unlike many existing 3D cancer models, the peptide gel is inert, apart from molec... ...
Modelling neurodegeneration and inflammation in early diabetic retinopathy using 3D human retinal organoidsAbstract
Purpose
Diabetic retinopathy (DR) is a complication of diabetes and a primary cause of visual impairment amongst working-age individuals. DR is a degenerative condition in which hyperglycaemia results in morphological and functional changes in certain retinal cells. Existing treatments main... ...
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