Cortical Spheroid Model for Studying the Effects of Ischemic Brain Injury
Tóm tắt
Từ khóa
Tài liệu tham khảo
Lipton P. Ischemic Cell Death in Brain Neurons. Physiol Rev. 1999;79:1431–568. https://doi.org/10.1152/physrev.1999.79.4.1431.
Mergenthaler P, Meisel A. Do stroke models model stroke? Dis Model Mech. 2012;5:718–25. https://doi.org/10.1242/dmm.010033.
Barthels D, Das H (2020) Current advances in ischemic stroke research and therapies. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866, 165260. https://doi.org/10.1016/j.bbadis.2018.09.012
Sommer CJ. Ischemic stroke: experimental models and reality. Acta Neuropathol. 2017;133:245–61. https://doi.org/10.1007/s00401-017-1667-0.
Jensen C, Teng Y (2020) Is It Time to Start Transitioning From 2D to 3D Cell Culture? Front Mol Biosci 7. https://doi.org/10.3389/fmolb.2020.00033
Van Breedam E, Ponsaerts P. Promising Strategies for the Development of Advanced In Vitro Models with High Predictive Power in Ischaemic Stroke Research. IJMS. 2022;23:7140. https://doi.org/10.3390/ijms23137140.
Lovett ML, Nieland TJF, Dingle YL, Kaplan DL. Innovations in 3D Tissue Models of Human Brain Physiology and Diseases. Adv Funct Mater. 2020;30:44. https://doi.org/10.1002/adfm.201909146.
Bhaduri A, et al. Cell stress in cortical organoids impairs molecular subtype specification. Nature. 2020;578:142–8. https://doi.org/10.1038/s41586-020-1962-0.
Dingle Y-TL, et al. Three-Dimensional Neural Spheroid Culture: An In Vitro Model for Cortical Studies. Tissue Eng Part C Methods. 2015;21:1274–83. https://doi.org/10.1089/ten.tec.2015.0135.
Boutin ME, et al. A three-dimensional neural spheroid model for capillary-like network formation. J Neurosci Methods. 2018;299:55–63. https://doi.org/10.1016/j.jneumeth.2017.01.014.
Sevetson JL, Theyel B, Hoffman-Kim D. Cortical spheroids display oscillatory network dynamics. Lab Chip. 2021;21:4586–95. https://doi.org/10.1039/D1LC00737H.
Zhu X, et al. Ultrafast optical clearing method for three-dimensional imaging with cellular resolution. Proc Natl Acad Sci USA. 2019;116:11480–9. https://doi.org/10.1073/pnas.1819583116.
Mehta SL (2014) Mechanisms of Stroke Induced Neuronal Death: Multiple Therapeutic Opportunities. Adv Anim Vet Sci 2, 438–446. https://doi.org/10.14737/journal.aavs/2014/2.8.438.446
Kharlamov A, et al. MAP2 Immunostaining in Thick Sections for Early Ischemic Stroke Infarct Volume in Non-Human Primate Brain. J Neurosci Methods. 2009;182:205–10. https://doi.org/10.1016/j.jneumeth.2009.06.014.
Hinman JD. The back and forth of axonal injury and repair after stroke. Curr Opin Neurol. 2014;27:615–23. https://doi.org/10.1097/WCO.0000000000000149.
Becerra-Calixto A, Cardona-Gómez GP. The Role of Astrocytes in Neuroprotection after Brain Stroke: Potential in Cell Therapy. Front Mol Neurosci. 2017;10:88. https://doi.org/10.3389/fnmol.2017.00088.
Sims NR, Yew WP. Reactive astrogliosis in stroke: Contributions of astrocytes to recovery of neurological function. Neurochem Int. 2017;107:88–103. https://doi.org/10.1016/j.neuint.2016.12.016.
Liu Z, Chopp M. Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke. Prog Neurobiol. 2016;144:103–20. https://doi.org/10.1016/j.pneurobio.2015.09.008.
Xu S, Lu J, Shao A, Zhang JH, Zhang J (2020) Glial Cells: Role of the Immune Response in Ischemic Stroke. Front Immunol 11. https://doi.org/10.3389/fimmu.2020.00294
Hu X, De Silva TM, Chen J, Faraci FM. Cerebral Vascular Disease and Neurovascular Injury in Ischemic Stroke. Circ Res. 2017;120:449–71. https://doi.org/10.1161/CIRCRESAHA.116.308427.
Jiang MQ, et al. Long-term Survival and Regeneration of Neuronal and Vasculature Cells inside the Core Region after Ischemic Stroke in Adult Mice. Brain Pathol. 2017;27:480–98. https://doi.org/10.1111/bpa.12425.
Freitas-Andrade M, Raman-Nair J, Lacoste B (2020) Structural and Functional Remodeling of the Brain Vasculature Following Stroke. Front Physiol 11. https://doi.org/10.3389/fphys.2020.00948
Tardiolo G, Bramanti P, Mazzon E. Overview on the Effects of N-Acetylcysteine in Neurodegenerative Diseases. Molecules. 2018;23:3305. https://doi.org/10.3390/molecules23123305.
Kalaria RN. The role of cerebral ischemia in Alzheimer’s disease. Neurobiol Aging. 2000;21:321–30. https://doi.org/10.1016/s0197-4580(00)00125-1.
Ng SY, Lee AYW. Traumatic Brain Injuries: Pathophysiology and Potential Therapeutic Targets. Front Cell Neurosci. 2019;13:528. https://doi.org/10.3389/fncel.2019.00528.
Karp NA, Reavey N. Sex bias in preclinical research and an exploration of how to change the status quo. Br J Pharmacol. 2019;176:4107–18. https://doi.org/10.1111/bph.14539.
Ramirez FD et al. (2017) Sex Bias Is Increasingly Prevalent in Preclinical Cardiovascular Research: Implications for Translational Medicine and Health Equity for Women. AHA Journals 2. https://doi.org/10.1161/CIRCULATIONAHA.116.026668.
Beery AK, Zucker I. Sex bias in neuroscience and biomedical research. Neurosci Biobehav Rev. 2011;35:565–72. https://doi.org/10.1016/j.neubiorev.2010.07.002.
Plevkova J et al. (2021) Various Aspects of Sex and Gender Bias in Biomedical Research. Physiol Res S367–S378 doi:https://doi.org/10.33549/physiolres.934593. https://doi.org/10.33549/physiolres.934593
Virani SS, et al. Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association. Circulation. 2020;141:e139–596. https://doi.org/10.1161/CIR.0000000000000757.
Hind WH, England TJ, O’Sullivan SE. Cannabidiol protects an in vitro model of the blood-brain barrier from oxygen-glucose deprivation via PPARγ and 5-HT 1A receptors: CBD modulates BBB permeability. Br J Pharmacol. 2016;173:815–25. https://doi.org/10.1111/bph.13368.
Potapova IA, Brink PR, Cohen IS, Doronin SV. Culturing of Human Mesenchymal Stem Cells as Three-dimensional Aggregates Induces Functional Expression of CXCR4 That Regulates Adhesion to Endothelial Cells. J Biol Chem. 2008;283:13100–7. https://doi.org/10.1074/jbc.M800184200.
Sandhu JK, et al. Molecular mechanisms of glutamate neurotoxicity in mixed cultures of NT2-derived neurons and astrocytes: Protective effects of coenzyme Q10. J Neurosci Res. 2003;72:691–703. https://doi.org/10.1002/jnr.10579.
Zhang W-H, et al. Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death. Proc Natl Acad Sci. 2003;100:16012–7. https://doi.org/10.1073/pnas.2534856100.
Jiang X, et al. Blood-brain barrier dysfunction and recovery after ischemic stroke. Prog Neurobiol. 2018;163–164:144–71. https://doi.org/10.1016/j.pneurobio.2017.10.001.
Bhalerao A, et al. In vitro modeling of the neurovascular unit: advances in the field. Fluids and Barriers of the CNS. 2020;17:22. https://doi.org/10.1186/s12987-020-00183-7.
King AE, Southam KA, Dittmann J, Vickers JC. Excitotoxin-induced caspase-3 activation and microtubule disintegration in axons is inhibited by taxol. Acta Neuropathol Commun. 2013;1:59. https://doi.org/10.1186/2051-5960-1-59.
Mages B, et al. Impaired Neurofilament Integrity and Neuronal Morphology in Different Models of Focal Cerebral Ischemia and Human Stroke Tissue. Front Cell Neurosci. 2018;12:161. https://doi.org/10.3389/fncel.2018.00161.
Zhang Z, Yan J, Taheri S, Liu KJ, Shi H. Hypoxia-inducible factor 1 contributes to N-acetylcysteine’s protection in stroke. Free Radical Biol Med. 2014;68:8–21. https://doi.org/10.1016/j.freeradbiomed.2013.11.007.
Turkmen S, et al. The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke. Am J Emerg Med. 2016;34:1804–7. https://doi.org/10.1016/j.ajem.2016.06.003.
Sekhon B, et al. N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia. Brain Res. 2003;971:1–8. https://doi.org/10.1016/S0006-8993(03)02244-3.
Khan M, et al. Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke. J Neurosci Res. 2004;76:519–27. https://doi.org/10.1002/jnr.20087.
Gouix E, et al. Oxygen glucose deprivation-induced astrocyte dysfunction provokes neuronal death through oxidative stress. Pharmacol Res. 2014;87:8–17. https://doi.org/10.1016/j.phrs.2014.06.002.
Lee Y-H, Lee S-R. Neuroprotective effects of N-acetylcysteine via inhibition of matrix metalloproteinase in a mouse model of transient global cerebral ischemia. Brain Res Bull. 2020;154:142–50. https://doi.org/10.1016/j.brainresbull.2019.10.004.