Hybrid immune response to parental liver tissue graftsImmunogenetics - Tập 17 - Trang 465-473 - 1983
Jane S. Schultz, Roberta DeMott-Friberg, Theodore F. Beals
Parental-to-F1-hybrid liver tissue grafts in like-sex donor-recipient combinations survive indefinitely, although several F1 recipients demonstrate an immunological response to the parental graft. Female F1 recipients, particularly those carrying theH-2
b haplotype, respond vigorously to male parental liver grafts. However F1 female responses to male parental liver tissue grafts differ substantive...... hiện toàn bộ
Methylation of the HLA-DR alpha gene is positively correlated with expressionImmunogenetics - Tập 26 - Trang 92-98 - 1987
Janet S. Lee, Linda O'Neill
We have evaluated the state of methylation of the HLA-DR alpha and HLA-DQ alpha genes in a set of melanoma cell lines which differ in their characteristic expression of these genes and a matching B-cell line. In contrast to the prevailing assumption that genes are methylated when their expression is repressed, we found that one particular site within the first intron of the DR alpha gene is methyl...... hiện toàn bộ
Definition of a novel complementation group in MHC class II deficiencyImmunogenetics - Tập 41 - Trang 287-294 - 1995
Ad Peijnenburg, Barbara Godthelp, Anette van Boxel-Dezaire, Peter J. van den Elsen
In this study we analyzed fibroblasts derived from an MHC class II deficiency patient (type III bare lymphocyte syndrome). Northern blot analysis showed that upon induction with IFN-γ these fibroblasts did not express HLA class II genes and displayed a strongly reduced level of HLA class I gene expression when compared with fibroblasts of a healthy individual. However, when analyzed by RT-polymera...... hiện toàn bộ
New chicken Rfp-Y haplotypes on the basis of MHC class II RFLP and MLC analysesImmunogenetics - Tập 45 - Trang 345-352 - 1997
H. R. Juul-Madsen, Rima Zoorob, Charles Auffray, Karsten Skjødt, Jan E. Hedemand
New chicken Rfp-Y haplotypes were determined by the use of restriction fragment length polymorphism (RFLP) and mixed lymphocyte culture (MLC) in four different chicken haplotypes, B
15
, B
19
, B
21
, B
201
. The RFLP polymorphism was mapped to the Rfp-Y syst...... hiện toàn bộ
Analysis of anchor residues in a naturally processed HLA-DR53 ligandImmunogenetics - - 1996
Hiroya Kobayashi, Taku Kokubo, Yusuke Abe, Keisuke Sato, Shoji Kimura, Naoyuki Miyokawa, Makoto Katagiri
The peptide motif of the HLA-DR53 (DRB4*0101) molecule, which is associated with autoimmune diseases including Vogt-Koyanagi-Harada's syndrome, was determined by peptide binding assay using human L plastin p581–595 peptide and its substituted analogues. L plastin p581–595 peptide is one of the naturally processed peptides bound to HLA-DR9/DR53 (DRB1*0901/DRB4*0101) molecules. The binding affinity ...... hiện toàn bộ