Immunogenetics
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The B6.CE-Lyb-2c:Mup-1 amouse strain contains the interferon-? genes from C57BL/6
Immunogenetics - - 1992
The primary structure of a feline class I gene: Striking similarity toHLA-A
Immunogenetics - Tập 30 - Trang 330-334 - 1989
The sequence of a feline class I pseudogene and its comparison with class I genes from other species is presented. The gene isolated is a pseudogene because of the presence of four stop codons and two frame shift mutations in the first-and second-domain encoding exons, as well as a mutation in a splice acceptor site in the third intron. By sequence comparison with the other class I sequences deter...... hiện toàn bộ
Variable domains in hagfish: NICIR is a polymorphic multigene family expressed preferentially in leukocytes and is related to lamprey TCR-like
Immunogenetics - Tập 58 - Trang 216-225 - 2006
The jawless vertebrates, represented by hagfish and lampreys, are the most advanced animals that apparently lack T cell and B cell receptors. As such, they offer unique opportunities for understanding the evolution of antigen receptors and variable (V)-type immunoglobulin (Ig)-like domains. In the present study, we describe four hagfish Ig superfamily (IgSF) members carrying V-type domains. None o...... hiện toàn bộ
CpG-rich sequences close to the site of duplication within the human IGH constant region
Immunogenetics - Tập 45 - Trang 365-370 - 1997
Human immunoglobulin heavy chains are encoded by a highly complex locus, IGH, which encompasses many transcriptional units, including nine alternative constant region genes. Much of the constant region gene cluster was duplicated during hominoid evolution. In rodents, IGH is known to be regulated by multiple elements, including several enhancers 3’ of the alpha chain-encoding A constant region ge...... hiện toàn bộ
Isoforms of the nonclassical class I MHC antigen H2-Q5 are enriched in brain and encode Qdm peptide
Immunogenetics - Tập 63 - Trang 57-64 - 2010
Although the human nonclassical class Ib major histocompatibility complex (Mhc) locus, HLA-G, is known to act as an immune suppressor in immune-privileged sites, little is currently known regarding participation of the rodent class Ib Mhc in similar pathways. Here, we investigated the expression properties of the mouse nonclassical Mhc H2-Q5
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Requirement for the location of both appropriate and irrelevant H-2 antigens on the same stimulator cell for unspecific DNA-synthesis inhibition by the H-2-antigen-primed, specific suppressor T cells
Immunogenetics - Tập 15 - Trang 167-176 - 1982
Specific suppressor T cells (SSTC), primed in vivo with H-2 antigens, have been shown previously to inhibit DNA synthesis in the one-way, three-cell mixed lymphocyte reaction (MLR) provided that (a) the stimulator cells bear the priming H-2 antigens, and (b) the responder cells possessIC+S regions homologous to those of the SSTC. Anti-B10.A BlO.A(2R) SSTC (anti-Dd) and anti-A.AL A.TL SSTC (anti-Kk...... hiện toàn bộ
Differential methylation pattern of the X-linked lymphoproliferative (XLP) disease gene SH2D1A correlates with the cell lineage-specific transcription
Immunogenetics - Tập 55 - Trang 116-121 - 2003
SH2D1A, the X-linked lymphoproliferative disease (XLP) gene, encodes a cytoplasmic protein that plays an essential role in controlling Epstein-Barr virus infection. It is expressed in T and NK cells, but not in B cells or in granulocytes. The promoter, the regulatory regions, as well as the mechanisms controlling its tissue-specific expression, are...... hiện toàn bộ
Molecular organization of the human CD3 gene family on chromosome 11q23
Immunogenetics - Tập 28 - Trang 365-373 - 1988
The genes encoding three invariant components of the human T-cell antigen receptor, the CD3 δ, γ, and ε chains, are located on human chromosome 11 at band q23. We isolated cosmid clones containing the human CD3 δ and γ chain genes in vectors designed for rapid and efficient chromosome “walking”. The human CD3ε gene was located in the region immediately downstream of the CD3 δ and γ genes using syn...... hiện toàn bộ
PIRCHE-II: an algorithm to predict indirectly recognizable HLA epitopes in solid organ transplantationAbstract Human leukocyte antigen (HLA) mismatches between donors and recipients may lead to alloreactivity after solid organ transplantation. Over the last few decades, our knowledge of the complexity of the HLA system has dramatically increased, as numerous new HLA alleles have been identified. As a result, the likelihood of alloreactive responses towards HLA misma... ... hiện toàn bộ
Immunogenetics - Tập 72 Số 1-2 - Trang 119-129 - 2020
Tổng số: 3,804
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