2′–5′ oligoadenylate synthetase and its relationship to HLA and genetic markers of insulin-dependent diabetes mellitus

Awad, J., Navarette, C., Sachs, J.A., Festenstein, H., Cassell, P.G., Niven, M.J., and Hitman, G.A.: HLA-DR, QD and DX alpha RFLPs and their associations with serologically defined HLA-DR and-DQ antigens.Immunogenetics 27: 73–76 1988

Bell, G.I., Horita, S., and Karam, J.H.: A highly polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus.Diabetes 33: 176–183, 1984

Boyum, A.: Isolation of mononuclear cells and granulocytes from human blood.Scan J Clin Lab Invest 21, (Suppl 97): 37–50, 1968

Carroll, M.C., Katzman, P., Alicot, E.M., Koller, B.H., Geraghty, D.E., Orr, H.T., Strominger, J.L., and Spies, T.: Linkage map of the human major histocompatibility complex including the tumour necrosis factor genes.Proc Natl Acad Sci USA 84: 8535–8539, 1987

Hitman, G. A., Tarn, A. C., Winter, R. M., Drummond, V., Williams, L. G., Jowett, N. I., Bottazza, G. F., and Galton, D. J.: Type 1 (insulin-dependent) diabetes and a highly variable locus close to the insulin gene on chromosome 11.Diabetologia 28: 218–222, 1985

Hitman, G. A., Niven, M. J., Festenstein, H., Cassell, P. G., Awad, J., Walker-Smith, J., Leonard, J. N., Fry, L., Ciclitira, P., Kumar, P., and Sachs, J. A.: HLA Class II alpha chain gene polymorphisms in patients with insulin-dependent diabetes mellitus, dermatitis herpetiformis and coeliac disease.J Clin Invest 79: 609–615, 1987

Merlin, G., Revel, M., and Wallach, D.: The interferon-induced enzyme oligo-iso-adenylate synthetase: rapid determination of its in vitro products.Anal Biochem 110: 190–196, 1981

Mestan, J., Digel, W., Mittnacht, S., Hillen, H., Blohm, D., Moller, A., Jacobsen, H., and Kirchner, H.: Antiviral effects of recombinant tumour necrosis factor in vitro.Nature 323: 816–819, 1986

Owerbach, D., and Nerup, J.: Restriction fragment length polymorphisms of the insulin gene in diabetes mellitus.Diabetes 31: 275–277, 1982

Pujol-Borrell, R., Todd, I., Doshi, M., Bottazzo, G. F. Sutton, R., Gray, P., Adolf, G., and Feldman, M.: HLA Class II induction in human islet cells by interferon gamma plus tumour necrosis factor or lymphotoxin.Nature 326: 304–306, 1987

Raum, D., Awdeh, Z., Yams, E. J., Alper, C. A., and Gabay, K. H.: Extended major histocompatibility complex haplotypes in Type 1 diabetes mellitus.J Clin Invest 74: 449–454, 1984

Sachs, J. A., Cudworth, A. G., Jaruquemada, D., Gorsuch, A. N., and Festenstein, H.: Type 1 diabetes and the HLA D locus.Diabetologia 418: 41–43, 1980

Saunders, M. E., Gewert, D. R., Tugwell, M. E., McMahon, M., and Williams, B. R. G.: Human 2–5A synthetase: characterisation of a novel cDNA and corresponding gene structure. EMBO J 4: 1761–1768, 1985

Shulman, L. M., Barker, P. E., Hart, J. T., Peters, P. G. M., and Ruddle, F. H.: Assignment of low molecular weight human (2′–5′)A synthetase to chromosome 11.Somatic Cell Mol Genet 10: 247–257, 1984

Spielman, R.S., Lee, J., Bodmer, W. F. Bodmer, J. G. and Trowsdale, J.: Six HLA-D region α chain genes on human chromosome 6: polymorphisms and associations of DCα related sequences with DR types.Proc Natl Acad Sci USA 81: 3461–3465, 1984

Svejgaard, A., Platz, P., and Ryder, L. P.. Insulin-dependent diabetes mellitus.In P. I. Terasaki (ed.):Histocompatibility Testing 1980, pp. 638–654, Tissue Typing Laboratory, Los Angeles, 1980

Taylor, K. W.: Environmental factors and diabetes.In A. H. Barnett (ed.):Immunogenetics of insulin-dependent diabetes, pp. 42–53, Pubs MTP Press Ltd, 1987

Thomsen, H., Platz, P., Anderson, O. O., Christy, M., Lyngsoe, J., Nerup, J., Rasmussen, K., Ryder, L. P., Nielsen, L. S., and Svejgaard, A.: MLC typing in juvenile diabetes mellitus and idiopathic Addison’s disease.Transplant Rev 22: 120–147, 1975

Todd, J. A., Bell, J. I., and McDevitt, H. O.: HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus.Nature 329: 599–604, 1987

Williams, B. R. G. and Fish, E. N.: Interferon and viruses: in vitro studies.In J. Taylor-Papadimitriou (ed.):Interferons: their impact in biology and medicine, Pubs Oxford University Press, Oxford, New York, Toronto, 1985

Williams, B. R. G., Saunders, M. E., and Willard, H.: Interferon regulated human 2–5A synthetase gene maps to chromosome 12.Somatic Cell Mol Genet 12: 402–408, 1986

Wolf, E., Spencer, K. M., and Cudworth, A. G.: The genetic susceptibility to Type 1 (insulin dependent) diabetes: analysis of the HLA-DR association.Diabetologia 24: 224–230, 1984

Wong, G. H. W. and Goeddel, D. V.: Tumour necrosis factors α and β inhibit virus replication and synergize with interferons.Nature 323: 819–822, 1986