Association between the lack ofHLA-DQw6 and the low incidence of multiple sclerosis in Hungarian Gypsies

Bauer, H. J.: Multiple sclerosis in Europe.J Neurol234: 195–206, 1987 Cohen, D., Le Gall, I., Marcadet, A., Font, M. P., Lalouel, J. M., and Dausset, J.: Clusters of HLA class II restriction fragments describe allelic series.Proc Natl Acad Sci USA 81:7870–7874, 1984 Font, M. P., Geuher, L., Betuel, H., Freidel, A. C., Dausset, J., and Cohen, D.: HLA-DR2, -DR5, and DRw6 associated Dw subtypes correlate with HLA-DRB and DQB restriction fragment length polymorphisms.Proc Natl Acad Sci USA 83: 3361–3365, 1986 Francis, D. A., Batchelor, J. R., McDonald, W. I., Hing, S. N., Dodi, I. A., Fielder, A. H. L., Hern, J. E. C., and Downie, A. W.: Multiple sclerosis in North-East Scotland: an association with HLADQwl.Brain 110: 181–196, 1987 Gyódi, E., Benczur, M., Pálffy, G., Was, M., Petrányi, G.,Földes, L., and Hollán, S. R.: Association between HLA-B7 DR2 and dysfunction of natural and antibody mediated cytotoxicity without connection with the deficient interferon production in multiple sclerosis.Hum Immunol 4: 209–217, 1982 Jacobson, S., Sorrentino, R., Nepom, G. T., McFarlin, D. E., and Strominger, J. L.: DNA restriction fragment length polymorphism of HLA-DR2: correlation with HLA-DR2-associated functions.J Neuroimmunol 12: 195–203, 1986 Marcadet, A., Massart, C., Semana, G., Fauchet, R., Sabouraud, O., Merienne, M., Dausset, J., and Cohen, D.: Association of class II HLA-DQβ chain DNA restriction fragments with multiple sclerosis.Immunogenetics 22: 93–96, 1985 Pálffy, G.: MS in Hungary including the Gypsy population.In Y. Kuroiawa and L. T. Kurland (eds.):Multiple Sclerosis East and West, pp. 149–157, Karger, Basel, 1982 Semana, G., Quillivic, F., Madigand, M., Merienne, M., Genetet, B., Sabouraud, O., and Fauchet, R.: HLA genetic factors involved in familial MS: RFLP study defines a particular DQwl subtype associated with the disease.In C. Confavreux, G. Aimard, M. Devic (eds.):Trends in European Multiple Sclerosis Research, pp. 21–26, Elsevier Science Biomedical Division, New York, 1988 Svejgaard, A., Platz, P., and Ryder, L. P.: HLA and disease. A survey.Immunol Rev 70: 193–218, 1983 Zeliszewski, D., Sterkers, G., Freidel, C., Gebuhrer, L., Betuel, H., and Levy, J. P.: Functional definition of HLA-DR and -DQ epitopes specific for DR2-short,DwFJO haplotype.Immunogenetics 23: 385–392, 1986