Validity of the Kihon Checklist for assessing frailty status Tập 16 Số 6 - Trang 709-715 - 2016
Shosuke Satake, Kazuyoshi Senda, Young‐Jae Hong, Hisayuki Miura, Hidetoshi Endo, Takashi Sakurai, Izumi Kondo, Kenji Toba
AimThe Kihon Checklist is extensively used in Japan to identify elderly persons who are at risk of requiring support/care. We aimed to determine whether or not the Kihon C...... hiện toàn bộ
Systematic review of the Kihon Checklist: Is it a reliable assessment of frailty? Tập 16 Số 8 - Trang 893-902 - 2016
Priscila Yukari Sewo Sampaio, Ricardo Aurélio Carvalho Sampaio, Minoru Yamada, Hidenori Arai
AimTo investigate whether the Kihon Checklist (KCL) can predict frailty and disability.MethodsThe studies analyzed for the present review were retrieved by searching electronic databases and other sources using the keywords “Kihon Checklist” and “Basic Checklist.” The articles were restricted ...... hiện toàn bộ
Effect of angiotensin II type 2 receptor on stroke, cognitive impairment and neurodegenerative diseases Tập 13 Số 1 - Trang 13-18 - 2013
Masaki Mogi, Masatsugu Horiuchi
Here, we briefly review the role of the renin–angiotensin system (RAS) in cognitive impairment and neurodegenerative disease, mainly discussing our experimental studies on the angiotensin II type 2 (AT2) receptor. Ischemic brain damage is enhanced in mice with overexpression of angiotensin II, with reduced cerebral blood flow in the penumbra and an increase in oxidativ...... hiện toàn bộ
Incidence of post‐stroke delirium and 1‐year outcome Tập 13 Số 1 - Trang 123-129 - 2013
Doris Ka Ying Miu, June Chui Yan Yeung
Introduction: Post‐stroke delirium is not uncommon, and is associated with poorer outcome, higher mortality, longer hospital stay and greater risk of post‐stroke dementia. We aim to identify the incidence of post‐stroke delirium, risk factors for its development and 1‐year outcome.Method: Consecutive patients aged >50 year...... hiện toàn bộ
Importance of research on peptidylarginine deiminase and citrullinated proteins in age‐related disease Tập 10 Số s1 - 2010
Akihito Ishigami, Naoki Maruyama
Peptidylarginine deiminases (PAD) are a group of post‐translational modification enzymes that citrullinate (deiminate) protein arginine residues in a calcium ion‐dependent manner. Enzymatic citrullination abolishes positive charges of native protein molecules, inevitably causing significant alterations in their structure and functions. Citrullinated protein has an important physiological p...... hiện toàn bộ
Classification of frailty using the Kihon checklist: A cluster analysis of older adults in urban areas Tập 17 Số 1 - Trang 69-77 - 2017
Takeshi Kera, Hisashi Kawai, Hideyo Yoshida, Hirohiko Hirano, Motonaga Kojima, Yoshinori Fujiwara, Kazushige Ihara, Shuichi Obuchi
AimFrailty is an important predictor of the need for long‐term care and hospitalization. Our aim was to categorize frailty in community‐dwelling older adults.MethodsThe present study was carried out in 2011–2013, and consisted of 1380 individuals over 65 years of age. Participants completed th...... hiện toàn bộ
Usefulness of chair stand time as a surrogate of gait speed in diagnosing sarcopenia Tập 17 Số 4 - Trang 659-661 - 2017
Takayuki Nishimura, Kazuhiko Arima, Takuhiro Okabe, Satoshi Mizukami, Yoshihito Tomita, Mitsuo Kanagae, Hisashi Goto, Itsuko Horiguchi, Yasuyo Abe, Kiyoshi Aoyagi
AimDetermining gait speed as a measure of physical performance is recommended in diagnosing sarcopenia. Gait speed measurements require a certain amount of space (e.g. a 6‐m course), and might not be feasible in clinical settings or heath checkup examination sites. We developed a formula to estimate chair stand time based on gait speed, and examined the v...... hiện toàn bộ