Geriatrics and Gerontology International

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Effect of angiotensin II type 2 receptor on stroke, cognitive impairment and neurodegenerative diseases
Geriatrics and Gerontology International - Tập 13 Số 1 - Trang 13-18 - 2013
Masaki Mogi, Masatsugu Horiuchi
Here, we briefly review the role of the renin–angiotensin system (RAS) in cognitive impairment and neurodegenerative disease, mainly discussing our experimental studies on the angiotensin II type 2 (AT2) receptor. Ischemic brain damage is enhanced in mice with overexpression of angiotensin II, with reduced cerebral blood flow in the penumbra and an increase in oxidativ...... hiện toàn bộ
Association of sleep condition and social frailty in community‐dwelling older people
Geriatrics and Gerontology International - Tập 19 Số 9 - Trang 885-889 - 2019
Sho Nakakubo, Takehiko Doi, Hyuma Makizako, Kota Tsutsumimoto, Satoshi Kurita, Minji Kim, Hideaki Ishii, Takao Suzuki, Hiroyuki Shimada
AimThis cross‐sectional study examined whether sleep duration and excessive daytime sleepiness (EDS) were associated with social frailty in community‐dwelling older people.MethodsA total of 4427 community‐dwelling older people (51.4% women, mean age 71.9 years) who met the entry criteria were ...... hiện toàn bộ
Relationship between psychological pain and death anxiety with comprehensive geriatric assessment in older adults
Geriatrics and Gerontology International - Tập 20 Số 11 - Trang 1056-1060 - 2020
Çağatay Çavuşoğlu, İbrahim İleri, Rana Tuna Doğrul, Cemile Özsürekçi, Hatice Çalışkan, Muhammet Cemal Kızılarslanoğlu, Berna Göker
AimPsychological pain refers to the torment that results from adverse experiences, such as loneliness, guilt, frustration, hopelessness or loss. Psychological pain may impair physical and psychosocial functioning of older adults. Death anxiety is associated with cognitive function deterioration, change to social environment and increased risk of depressio...... hiện toàn bộ
Application of segmental bioelectrical impedance spectroscopy to the assessment of skeletal muscle cell mass in elderly men
Geriatrics and Gerontology International - Tập 14 Số S1 - Trang 129-134 - 2014
Yosuke Yamada, Kaori Matsuda, Mikko Björkman, Misaka Kimura
AimIt is important to assess not only the total skeletal muscle mass, but also the intracellular and extracellular compartments of skeletal muscle to examine the actual relationship between skeletal muscle mass and physical functions. Segmental bioelectrical impedance spectroscopy is a unique tool with which to assess intracellular and extracellular water...... hiện toàn bộ
Effects of physical exercise prescribed by a medical support team on elderly lower extremity osteoarthritis combined with metabolic syndrome and/or type 2 diabetes
Geriatrics and Gerontology International - Tập 12 Số 3 - Trang 446-453 - 2012
Masahiro Yokochi, Tomoyuki Watanabe, Kunio Ida, Kazuhito Yoshida, Yuzo Sato
Aim:  The aims of the present study were to investigate the effectiveness of exercise intervention provided by a medical support team specializing in lifestyle‐related diseases in the treatment of elderly lower extremity osteoarthritis and to examine the influence of bodyweight decrease on changes in the evaluation indexes.Methods: ... hiện toàn bộ
Predictors of non‐pharmacological intervention effect on cognitive function and behavioral and psychological symptoms of older people with dementia
Geriatrics and Gerontology International - Tập 17 Số S1 - Trang 28-35 - 2017
T. G. Hsu, Harry Tsai, An‐Chun Hwang, Liang‐Yu Chen, Liang‐Kung Chen
AbstractAimOur previous work showed that non‐pharmacological interventions could effectively reduce the severity of behavioral and psychological symptoms of dementia (BPSD), while the factors influencing the effect of intervention were less explored. Therefore, the main purpose of the present study was to investigate the predictor...... hiện toàn bộ
Risk factors and prognostic implications of aspiration pneumonia in older hip fracture patients: A multicenter retrospective analysis
Geriatrics and Gerontology International - Tập 19 Số 2 - Trang 119-123 - 2019
Seong‐Eun Byun, Hyun‐Chul Shon, Ji Wan Kim, Hyung Kyung Kim, Young-Suk Sim
AimThe present study aimed to investigate the risk factors and prognostic implications of aspiration pneumonia in older hip fracture patients.MethodsA total of 394 female and 125 male hip fracture patients aged ≥60 years who underwent surgery between 2015 and 2018 were retrospectively analyzed...... hiện toàn bộ
Incidence of post‐stroke delirium and 1‐year outcome
Geriatrics and Gerontology International - Tập 13 Số 1 - Trang 123-129 - 2013
Doris Ka Ying Miu, June Chui Yan Yeung
Introduction:  Post‐stroke delirium is not uncommon, and is associated with poorer outcome, higher mortality, longer hospital stay and greater risk of post‐stroke dementia. We aim to identify the incidence of post‐stroke delirium, risk factors for its development and 1‐year outcome.Method:  Consecutive patients aged >50 year...... hiện toàn bộ
The turn formation at positions 22 and 23 in the 42‐mer amyloid β peptide: The emerging role in the pathogenesis of Alzheimer's disease
Geriatrics and Gerontology International - Tập 10 Số s1 - 2010
Kazuma Murakami, Yuichi Masuda, Takuji Shirasawa, Takahiko Shimizu, Kazuhiro Irie
One hallmark of Alzheimer's disease (AD) is the accumulation of amyloid β (Aβ) peptides in the brain; Aβ mainly consists of 42‐mer and 40‐mer peptides (Aβ42 and Aβ40). Aβ42 plays a more critical role in the pathogenesis of AD because Aβ42 aggregates much faster and is more toxic than Aβ40. Therefore, there is an urgent need to elucidate the mechanism of aggregation and neurotoxicity of Aβ4...... hiện toàn bộ
Optimal energy distribution of carbohydrate intake for Japanese elderly patients with type 2 diabetes: The Japanese Elderly Intervention Trial
Geriatrics and Gerontology International - Tập 12 Số s1 - Trang 41-49 - 2012
Chiemi Kamada, Hidenori Yoshimura, Ryota Okumura, Keiko Takahashi, Satoshi Iimuro, Yasuo Ohashi, Atsushi Araki, Hiroyuki Umegaki, Takashi Sakurai, Yukio Yoshimura, Hideki Ito
Aim:  In diet therapy for diabetes, optimal energy intake and the energy distribution of macronutrients (protein : fat : carbohydrate [PFC] energy ratio) are important. We aimed to clarify the correlation between the PFC energy ratio and metabolic parameters including glycated hemoglobin A1c (HbA1c) and triglycerides in Japanese elderly patients with type 2 diabetes ...... hiện toàn bộ
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