An 8-week freeze-dried blueberry supplement impacts immune-related pathways: a randomized, double-blind placebo-controlled trialGenes and Nutrition - Tập 16 - Trang 1-19 - 2021
Michèle Rousseau, Justine Horne, Frédéric Guénard, Juan de Toro-Martín, Véronique Garneau, Valérie Guay, Michèle Kearney, Geneviève Pilon, Denis Roy, Patrick Couture, Charles Couillard, André Marette, Marie-Claude Vohl
Blueberries contain high levels of polyphenolic compounds with high in vitro antioxidant capacities. Their consumption has been associated with improved vascular and metabolic health. The objective was to examine the effects of blueberry supplement consumption on metabolic syndrome (MetS) parameters and potential underlying mechanisms of action. A randomized double-blind placebo-controlled interve...... hiện toàn bộ
25(OH)Vitamin D and autism spectrum disorder: genetic overlap and causalityGenes and Nutrition - - 2023
GuoSheng Yu, MinZhi Xu, Yao Chen, HaiYan Ke
To identify whether there exists a genetic correlation and causal relationship between 25(OH)D and autism spectrum disorder (ASD). Based on large-scale genome-wide association studies, a series of genetic approaches were adopted to obtain summary statistics. Using linkage disequilibrium score regression, we assessed the shared polygenic structure between traits and performed pleiotropic analysis u...... hiện toàn bộ
The challenges for molecular nutrition research 2: quantification of the nutritional phenotypeGenes and Nutrition - Tập 3 - Trang 51-59 - 2008
Ben van Ommen, Jaap Keijer, Robert Kleemann, Ruan Elliott, Christian A. Drevon, Harry McArdle, Mike Gibney, Michael Müller
In quantifying the beneficial effect of dietary interventions in healthy subjects, nutrition research meets a number of new challenges. Inter individual variation in biomarker values often is larger than the effect related to the intervention. Healthy subjects have a remarkable capacity to maintain homeostasis, both through direct metabolic regulation, metabolic compensation of altered diets, and ...... hiện toàn bộ
Circulating microRNAs are associated with early childhood obesity: results of the I.Family StudyGenes and Nutrition - Tập 14 - Trang 1-13 - 2019
Giuseppe Iacomino, Paola Russo, Pasquale Marena, Fabio Lauria, Antonella Venezia, Wolfgang Ahrens, Stefaan De Henauw, Pasquale De Luca, Ronja Foraita, Kathrin Günther, Lauren Lissner, Dénes Molnár, Luis A. Moreno, Michael Tornaritis, Toomas Veidebaum, Alfonso Siani
Nearly 10 years ago, the World Health Organization reported the increasing prevalence of overweight and obesity worldwide as a challenge for public health due to the associated adverse consequences. Epidemiological studies established a firm relationship between an elevated body mass index and chronic conditions such as diabetes, dyslipidemia, hypertension, heart disease, non-alcoholic fatty liver...... hiện toàn bộ
Genetic and environmental influences on nutrient intakeGenes and Nutrition - Tập 8 - Trang 241-252 - 2012
Jianghong Liu, Catherine Tuvblad, Adrian Raine, Laura Baker
The relationship between genetic and the environment represents a pathway to better understand individual variations in nutrition intake and food preferences. However, the present literature is weakened somewhat by methodological flaws (e.g., overreliance on self-report questionnaires), discrepancies in statistical approaches, and inconsistent findings. Little research on this topic to date has in...... hiện toàn bộ
Differential effects of basolateral and apical iron supply on iron transport in Caco-2 cellsGenes and Nutrition - Tập 10 - Trang 1-15 - 2015
J. J. Eady, Y. M. Wormstone, S. J. Heaton, B. Hilhorst, R. M. Elliott
Iron homeostasis in the human body is maintained primarily through regulation of iron absorption in the duodenum. The liver peptide hepcidin plays a central role in this regulation. Additionally, expression and functional control of certain components of the cellular iron transport machinery can be influenced directly by the iron status of enterocytes. The significance of this modulation, relativ...... hiện toàn bộ