An 8-week freeze-dried blueberry supplement impacts immune-related pathways: a randomized, double-blind placebo-controlled trialGenes and Nutrition - Tập 16 - Trang 1-19 - 2021
Michèle Rousseau, Justine Horne, Frédéric Guénard, Juan de Toro-Martín, Véronique Garneau, Valérie Guay, Michèle Kearney, Geneviève Pilon, Denis Roy, Patrick Couture, Charles Couillard, André Marette, Marie-Claude Vohl
Blueberries contain high levels of polyphenolic compounds with high in vitro antioxidant capacities. Their consumption has been associated with improved vascular and metabolic health. The objective was to examine the effects of blueberry supplement consumption on metabolic syndrome (MetS) parameters and potential underlying mechanisms of action. A randomized double-blind placebo-controlled interve...... hiện toàn bộ
25(OH)Vitamin D and autism spectrum disorder: genetic overlap and causalityGenes and Nutrition - - 2023
GuoSheng Yu, MinZhi Xu, Yao Chen, HaiYan Ke
To identify whether there exists a genetic correlation and causal relationship between 25(OH)D and autism spectrum disorder (ASD). Based on large-scale genome-wide association studies, a series of genetic approaches were adopted to obtain summary statistics. Using linkage disequilibrium score regression, we assessed the shared polygenic structure between traits and performed pleiotropic analysis u...... hiện toàn bộ
Differential effects of basolateral and apical iron supply on iron transport in Caco-2 cellsGenes and Nutrition - Tập 10 - Trang 1-15 - 2015
J. J. Eady, Y. M. Wormstone, S. J. Heaton, B. Hilhorst, R. M. Elliott
Iron homeostasis in the human body is maintained primarily through regulation of iron absorption in the duodenum. The liver peptide hepcidin plays a central role in this regulation. Additionally, expression and functional control of certain components of the cellular iron transport machinery can be influenced directly by the iron status of enterocytes. The significance of this modulation, relativ...... hiện toàn bộ
Advances in genomics for flatfish aquacultureGenes and Nutrition - Tập 8 - Trang 5-17 - 2012
Joan Cerdà, Manuel Manchado
Fish aquaculture is considered to be one of the most sustainable sources of protein for humans. Many different species are cultured worldwide, but among them, marine flatfishes comprise a group of teleosts of high commercial interest because of their highly prized white flesh. However, the aquaculture of these fishes is seriously hampered by the scarce knowledge on their biology. In recent years, ...... hiện toàn bộ
Evidence for the association between FTO gene variants and vitamin B12 concentrations in an Asian Indian populationGenes and Nutrition - Tập 14 - Trang 1-9 - 2019
Shelini Surendran, Ramamoorthy Jayashri, Lauren Drysdale, Dhanasekaran Bodhini, Nagarajan Lakshmipriya, Coimbatore Subramanian Shanthi Rani, Vasudevan Sudha, Julie A. Lovegrove, Ranjit M. Anjana, Viswanathan Mohan, Venkatesan Radha, Rajendra Pradeepa, Karani S. Vimaleswaran
Low vitamin B12 concentrations have been associated with major clinical outcomes, including adiposity, in Indian populations. The Fat mass and obesity-associated gene (FTO) is an established obesity-susceptibility locus; however, it remains unknown whether it influences vitamin B12 status. Hence, we investigated the association of two previously studied FTO polymorphisms with vitamin B12 concentra...... hiện toàn bộ