Genetic predisposition to type 2 diabetes is associated with impaired insulin secretion but does not modify insulin resistance or secretion in response to an intervention to lower dietary saturated fat

Genes and Nutrition - Tập 7 Số 4 - Trang 529-536 - 2012
Celia G. Walker1, Ruth J.F. Loos2, Adrian P. Mander3, Susan A. Jebb1, Gary Frost4, Bruce A. Griffin5, Julie A. Lovegrove6, Thomas Sanders7, Les Bluck1
1MRC Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge, CB1 9NL, UK
2MRC Epidemiology Unit, Institute of Medical Science, Addenbrooke’s Hospital, Cambridge, UK
3MRC Biostatistics Unit Hub for Trials Methodology Research, Institute of Public Health, Cambridge, UK
4Nutrition and Dietetic Research Group, Imperial College London, London, UK
5Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
6Hugh Sinclair Unit of Human Nutrition, Institute for Cardiovascular and Metabolic Research (IMCR), University of Reading, Reading, UK
7Nutritional Sciences Division, Kings College London, London, UK

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