Fühner-Wieland's Sammlung von Vergiftungsfällen

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Toxicity and carcinogenicity of furan in human diet
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 84 Số 7 - Trang 563-578 - 2010
Nadiya Bakhiya, Klaus E. Appel
Genetic and epigenetic cancer chemoprevention on molecular targets during multistage carcinogenesis
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 90 - Trang 2389-2404 - 2016
Hyung Sik Kim, Sam Kacew, Byung Mu Lee
The main goal of cancer chemoprevention is to prevent or halt the progression of carcinogenesis with the administration of synthetic or natural compounds. Fundamental chemopreventive strategies include inhibition of genetic damage, anti-proliferation/cell cycle regulation, and induction of apoptosis and anti-inflammatory processes, which may be critical for carcinogenesis intervention. Recently, a...... hiện toàn bộ
Toxicological assessment of magnesium oxide nanoparticles in HT29 intestinal cells
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 93 - Trang 1491-1500 - 2019
Anna Mittag, Thomas Schneider, Martin Westermann, Michael Glei
Nanoparticles (NPs) are increasingly used in different consumer-related areas, for instance in food packaging or as additives, because of their enormous potential. Magnesium oxide (MgO) is an EU-approved food additive (E number 530). It is commonly used as a drying agent for powdered foods, for colour retention or as a food supplement. There are no consistent results regarding the effects of oral ...... hiện toàn bộ
Aristolochic acid IVa forms DNA adducts in vitro but is non-genotoxic in vivo
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 95 - Trang 2839-2850 - 2021
Jingjing Wan, Ruixue Chen, Zhou Yang, Jing Xi, Yiyi Cao, Yu Chen, Xinyu Zhang, Yang Luan
Aristolochic acids (AAs) are a family of natural compounds with AA I and AA II being known carcinogens, whose bioactivation causes DNA adducts formation. However, other congeners have rarely been investigated. This study aimed to investigate genotoxicity of AA IVa, which differs from AA I by a hydroxyl group, abundant in Aristolochiaceae plants. AA IVa reacted with 2'-deoxyadenosine (dA) and 2'-de...... hiện toàn bộ
Age-related effects of chlorpyrifos on muscarinic receptor-mediated signaling in rat cortex
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 75 - Trang 676-684 - 2001
Hengshan Zhang, Jing Liu, Carey N. Pope
Chlorpyrifos (CPF) is a widely used organophosphorus pesticide. Earlier work from our laboratory and others has demonstrated that the sensitivity to CPF exposure changes markedly during maturation. A number of studies suggest that in addition to inhibiting acetylcholinesterase (AChE), CPF oxon may also interact directly with m2 and/or m4 subtypes of muscarinic acetylcholine receptors (mAChRs). In...... hiện toàn bộ
Developmental exposure to T-2 toxin reversibly affects postnatal hippocampal neurogenesis and reduces neural stem cells and progenitor cells in mice
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 90 - Trang 2009-2024 - 2015
Takeshi Tanaka, Hajime Abe, Masayuki Kimura, Nobuhiko Onda, Sayaka Mizukami, Toshinori Yoshida, Makoto Shibutani
To determine the developmental exposure effects of T-2 toxin on postnatal hippocampal neurogenesis, pregnant ICR mice were provided a diet containing T-2 toxin at 0, 1, 3, or 9 ppm from gestation day 6 to day 21 on weaning after delivery. Offspring were maintained through postnatal day (PND) 77 without T-2 toxin exposure. In the hippocampal dentate gyrus of male PND 21 offspring, GFAP+ and BLBP+ t...... hiện toàn bộ
Tollkirschen-Vergiftung (tödliche?) (Giftmord?)
Fühner-Wieland's Sammlung von Vergiftungsfällen - - 1931
H. Merkel, J. Sedlmeyer, Wesley E. Straub
Loss of microRNA-21 protects against acetaminophen-induced hepatotoxicity in mice
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 97 - Trang 1907-1925 - 2023
Alexandra M. Huffman, Maryam Syed, Samar Rezq, Christopher D. Anderson, Licy L. Yanes Cardozo, Damian G. Romero
Acetaminophen (APAP)-induced Acute Liver Failure (ALF) is recognized as the most common cause of ALF in Western societies. APAP-induced ALF is characterized by coagulopathy, hepatic encephalopathy, multi-organ failure, and death. MicroRNAs are small, non-coding RNAs that regulate gene expression at the post-transcriptional level. MicroRNA-21 (miR-21) is dynamically expressed in the liver and is in...... hiện toàn bộ
Reactivators of organophosphate-inhibited cholinesterase
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 49 - Trang 285-291 - 1982
Vjera Deljac, Matej Maksimović, Ljiljana Radović, Dušanka Rakin, Verica Markov, Ivo Bregovec, Zlatko Binenfeld
Eleven isomeric phenylhydroxymethyl and cyclohexylhydroxymethyl derivatives of 1-(2-hydroxyiminomethyl-1-pyridinio)-3-(1-pyridinio)-2-oxapropane diiodide and 1-(4-hydroxyiminomethyl-1-pyridinio)-3-(1-pyridinio)-2-oxapropane diiodide were prepared and characterized by spectroscopic methods and pKa values. The inhibitory power (I50) of the investigated oximes was determined on purified bovine erythr...... hiện toàn bộ
Inhibition of lymphocytic neuropathy target esterase predicts the development of organophosphate-induced delayed polyneuropathy
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 59 Số 3 - Trang 176-179 - 1986
Marcello Lotti, Angelo Moretto, Roberto Zoppellari, Raffaella Dainese, Nicolo’ Rizzuto, G Barusco
Tổng số: 5,964   
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