Fühner-Wieland's Sammlung von Vergiftungsfällen
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The high sensitivity of the rabbit to the teratogenic effects of 13-cis-retinoic acid (isotretinoin) is a consequence of prolonged exposure of the embryo to 13-cis-retinoic acid and 13-cis-4-oxo-retinoic acid, and not of isomerization to all-trans-retinoic acid
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 68 - Trang 119-128 - 1994
Previous studies suggested that the rabbit is much more susceptible to the teratogenic action of 13-cis-retinoic acid (13-cis-RA) than the mouse or the rat, while the teratogenicity of all-trans-RA was comparable in these species. In the present study we investigated if pharmacokinetics can explain these species- and structure-related differences. The embryotoxic and teratogenic potential of all-t...... hiện toàn bộ
Beiträge zum Nachweis von E 605
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 16 - Trang 401-407 - 1957
Im Mageninhalt von E 605-Suicidfällen, der bei Zimmertemperatur aufbewahrt worden war, ließ sich noch nach 8 Monaten der Wirkstoff des E 605 mit Hilfe der spezifischen UV-Absorptionskurve nachweisen. Bei Versuchen mit kleineren zugesetzten Mengen an E 605 zu Mageninhalt, war die Nachweisbarkeitsdauer mit der beschriebenen Methode kürzer. Nach dreiwöchigem Erdgrab konnte im Mageninhalt von Kaninche...... hiện toàn bộ
Beitrag zur Therapie der Botulinus-Intoxikation
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 28 - Trang 302-304 - 1972
Das Gift von Latrodectus Tredecimguttatus, das an der demyelisierten motorischen Faser Acetylcholin freizusetzen vermag, verlängert an Mäusen mit Vergiftung durch Botulinus-Toxin A signifikant die Überlebenszeit.
Effect of triphenyltin chloride on the release of histamine from mast cells
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 66 Số 7 - Trang 514-517 - 1992
Suppressive effect of enzymatically modified isoquercitrin on phenobarbital-induced liver tumor promotion in rats
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 85 - Trang 1475-1484 - 2011
To investigate the effect of enzymatically modified isoquercitrin (EMIQ) on hepatocellular tumor promotion induced by phenobarbital (PB), male rats were administered a single intraperitoneal injection of 200 mg/kg N-diethylnitrosamine (DEN) and then fed with a diet containing PB (500 ppm) for 8 weeks, with or without EMIQ (2,000 ppm) in the drinking water. One week after PB administration, rats un...... hiện toàn bộ
The carcinogenicity of discontinuous inhaled benzene exposures in CD-1 and C57Bl/6 mice
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 62 - Trang 331-335 - 1988
Groups of male C57Bl and CD-1 mice were exposed to benzene via inhalation using two different exposure protocols. One protocol consisted of repetitive week-long exposures to 300 ppm benzene (6 h/d×5 d/wk) interrupted by 2 weeks of non-exposure. The exposure pattern (1 week of exposure followed by 2 weeks of non-exposure) was continued until the death of the last exposed animal. The second protocol...... hiện toàn bộ
New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 95 - Trang 1413-1429 - 2021
2C (2C-x) is the general name for the family of phenethylamines containing two methoxy groups at the 2 and 5 positions of the benzene ring. The abuse of 2C family drugs has grown rapidly, although the abuse potential and neurotoxic properties of 2C drugs have not yet been fully investigated. In this study, we investigated the abuse potential and neurotoxicity of 4-chloro-2,5-dimethoxyphenethylamin...... hiện toàn bộ
Autocrine effect of EGFR ligands on the pro-inflammatory response induced by PM2.5 exposure in human bronchial epithelial cells
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 86 - Trang 1537-1546 - 2012
Human exposure to PM2.5 (particulate matter with an aerodynamic diameter below 2.5 μm) is known to be responsible for airway inflammation and may also induce airway remodelling. In respiratory epithelial cells exposed to PM2.5, releases of pro-inflammatory cytokines such as granulocyte macrophage-colony stimulating factor (GM-CSF) and growth factor ligands of the epidermal growth factor receptor (...... hiện toàn bộ
Secretion of human chorionic gonadotropin in superfused young placental tissue exposed to cadmium
Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 66 Số 2 - Trang 95-99 - 1992
Tổng số: 5,966
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