In vitro absorption of some chlorinated paraffins through human skin

Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 63 - Trang 425-426 - 1989
Robert C. Scott1
1Biochemical Toxicology Section, ICI Central Toxicology Laboratory, Nr Macclesfield, UK

Tóm tắt

The in vitro absorption of chlorinated paraffins, Cereclor S52 and Cereclor 56L (present in a cutting fluid), has been measured through human skin. During 56 h continuous skin contact no Cereclor S52 was detected to have been absorbed and only a very slow rate of Cereclor 56L absorption (mean rate, 0.04 μg/cm/h) was measured. This rate was only apparent after more than 7 h continuous skin contact. These chlorinated paraffins were very poorly absorbed through human skin and human dermal exposure should not cause significant systemic levels.

Tài liệu tham khảo

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