Electrophoresis
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Evaluation of enantioselective binding of basic drugs to plasma by ACEAbstract The present paper deals with the evaluation of the stereoselective binding of antihistamines (brompheniramine, chlorpheniramine, hydroxyzine, orphenadrine and phenindamine), phenothiazines (promethazine and trimeprazine) and a local anesthetic (bupivacaine) to human plasma proteins. Since all of them are drugs highly bound to proteins, a methodology to dete... ... hiện toàn bộ
Electrophoresis - Tập 28 Số 17 - Trang 3056-3063 - 2007
Capillary electrochromatography with packed bead beds in microfluidic devicesAbstract Microchip‐based bead‐packed columns for electrochromatography are described for several types of stationary phases. Chromatography columns 2 mm in length were used for the separation of proteins and peptides by size‐ and ion‐exchange modes of separation, respectively. In size‐exclusion electrochromatograpgy, FITC‐IgG and FITC‐insulin were baseline resolved ... ... hiện toàn bộ
Electrophoresis - Tập 30 Số 24 - Trang 4237-4244 - 2009
Recent innovations in protein separation on microchips by electrophoretic methods: An updateAbstract Lab‐on‐a‐chip electrophoresis is becoming increasingly useful for protein analysis, thanks to recent developments in this field. This review is an update of the review we published at the start of 2008 [Peng, Y., Pallandre, A., Tran, N. T., Taverna, M., Electrophoresis 2008, 29 , 156–177]. The superiority... ... hiện toàn bộ
Electrophoresis - Tập 31 Số 1 - Trang 147-173 - 2010
Cardiac protein abnormalities in dilated cardiomyopathy detected by two‐dimensional polyacrylamide gel electrophoresisAbstract The aim of the investigation was to determine whether there are specific global quantitative and qualitative changes in protein expression in heart tissue from patients with dilated cardiomyopathy (DCM) compared with ischaemic heart disease and undiseased tissue. Two‐dimensional (2‐D) polyacrylamide gel electrophoresis and computer analysis was used to stud... ... hiện toàn bộ
Electrophoresis - Tập 19 Số 11 - Trang 2031-2042 - 1998
Protein expression profiles in human breast ductal carcinoma and histologically normal tissueAbstract Reference two‐dimensional (2‐D) gels are presented for human breast ductal carcinoma and histologically normal tissue. Whole biopsy fragments were analyzed, including epithelial and nonepithelial components. Thirty‐five spots have been assigned by gel matching to the human liver SWISS‐2DPAGE reference map and/or to the human primary keratinocyte IPG map fro... ... hiện toàn bộ
Electrophoresis - Tập 18 Số 15 - Trang 2832-2841 - 1997
Electrophoresis of soft particles: Analytic approximationsAbstract An approximate analytic expression is derived for the electrophoretic mobility of a weakly charged spherical soft particle (i.e. , a hard particle covered with a weakly charged polyelectrolyte layer) on the basis of the general mobility expression for soft particles (Ohshima, H., J. Colloid Interface Sci. ... ... hiện toàn bộ
Electrophoresis - Tập 27 Số 3 - Trang 526-533 - 2006
Recent advances on capillary columns, detectors, and two‐dimensional separations in capillary electrochromatographyAs a typical miniaturized analytical technique, CEC has attracted much attention because of its low sample and solvent consumption, high efficiency, high selectivity, high resolution, and fast speed. In this review, we mainly cover the development of capillary columns and detection techniques in the CEC since 2009. Herein, three types of capillary columns, namely, open‐tubular capillary co... ... hiện toàn bộ
Electrophoresis - Tập 36 Số 1 - Trang 124-134 - 2015
Production of β‐Lactoglobulin hydrolysates by monolith based immobilized trypsin reactorsAbstract Tryptic hydrolysis of β‐Lactoglobulin (β‐Lg) is attracting more and more attention due to the reduced allergenicity and the functionality of resulting hydrolysates. To produce hydrolysates in an economically viable way, immobilized trypsin reactors (IMTRs), based on polymethacrylate monolith with pore size 2.1 μm (N1) and 6 μm (N2), were developed and used ... ... hiện toàn bộ
Electrophoresis - Tập 38 Số 22-23 - Trang 2947-2956 - 2017
Liquid–liquid ion transport junctions based on paired gold electrodes in generator–collector modeAbstract Simultaneous electrochemically driven double anion transfer across liquid–liquid interfaces is demonstrated at a gold–gold junction electrode. In the presence of two closely spaced electrodes (generator and collector), anion uptake into the organic phase (oxidation) and anion expulsion into the aqueous phase (reduction) can be combined to result in a genera... ... hiện toàn bộ
Electrophoresis - Tập 30 Số 19 - Trang 3361-3365 - 2009
Capillary electrophoresis analysis of a wide variety of seized drugs using the same capillary with dynamic coatingsAbstract Capillary electrophoresis methodology is presented for the routine analysis of a wide variety of seized drugs using the same capillary with dynamic coatings and multiple run buffers. The types of exhibits analyzed using diode array UV detection include phenethylamines, cocaine, oxycodone, heroin, lysergic acid diethylamide (LSD), opium, hallucinogenic mushr... ... hiện toàn bộ
Electrophoresis - Tập 25 Số 10-11 - Trang 1580-1591 - 2004
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