ABO blood grouping and COVID-19: a hospital-based study in Eastern IndiaEgyptian Journal of Medical Human Genetics - - 2022
B.F.Sc. Harapriya Behera, Bidyutprava Rout, RajashreePanigrahy, Subrat Kumar Kar, Debasish Sahoo, Kundan Kumar Sahu, Sarita Otta
Abstract
Background
Blood group has been stated to be one of the risk factors associated with viral diseases like dengue, hepatitis virus, Norwalk virus and even the coronavirus associated with 2003 severe acute respiratory syndrome (SARS) outbreak. In addition, anti-A antibodies in experimental mod...... hiện toàn bộ
Exome sequencing identifies a novel GUCY2D mutation in an Iranian family with Leber congenital amaurosis-1: a case reportEgyptian Journal of Medical Human Genetics - Tập 23 - Trang 1-4 - 2022
Mostafa Neissi, Adnan Issa Al-Badran, Javad Mohammadi-Asl
Leber congenital amaurosis (LCA), the severe form of inherited retinal degenerative disorder, is a prevalent disorder in the first year of life. Recently, genetic studies discovered that different gene mutations are responsible for LCA clinical manifestations.
In this study, we applied whole exome sequencing (WES) to identify probable gene defects in an Iranian girl with LCA-1. We found a novel d...... hiện toàn bộ
Genotype association of IP6K3 gene with Hashimoto’s thyroiditis in Algerian population (Aures region)Egyptian Journal of Medical Human Genetics - - 2020
Warda Kherrour, Dean Kaličanin, Luka Brčić, Leila Hambaba, Mouloud Yahia, S. Benbia, Vesna Boraska Perica
Abstract
Background
Hashimoto’s thyroiditis (HT) is a chronic autoimmune disease of the thyroid gland and is also the main cause of hypothyroidism. A recent genome-wide association study (GWAS) suggested an association of three novel genetic variants with HT in a population of Caucasian origin (Croatian). A case-control study was ...... hiện toàn bộ
Molecular analysis of CFTR gene mutations among Iraqi cystic fibrosis patientsEgyptian Journal of Medical Human Genetics - Tập 22 - Trang 1-7 - 2021
Asal Gailan Abdul-Qadir, Bassam Musa Al-Musawi, Rabab Farhan Thejeal, Saad Abdul-Baqi Al-Omar
Cystic fibrosis (CF) is an autosomal recessive multisystem disease that results from mutation(s) of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. More than 2100 mutations and polymorphisms have been reported in this gene so far. Incidence and genotyping of CF are under-identified in Iraq. This study aims to determine the types and frequencies of certain CFTR mutations among ...... hiện toàn bộ