Markers of neural degeneration and regeneration in Down syndrome patients

Gladzicki, 2001, The cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models, Brain Res Brain Res Rev, 35, 115, 10.1016/S0926-6410(00)00074-4 Rahmani, 1989, Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome, Proc Natl Acad Sci USA, 86, 5958, 10.1073/pnas.86.15.5958 Fuentes, 2000, Hum Mol Genet, 9, 1681, 10.1093/hmg/9.11.1681 Tanzi, 1987, Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus, Science, 235, 880, 10.1126/science.2949367 Goldgaber, 1987, Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer’s disease, Science, 235, 877, 10.1126/science.3810169 Robakis, 1987, Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neuritic (senile) plaques of people with Alzheimer disease and Down syndrome, Lancet, 1, 384, 10.1016/S0140-6736(87)91754-5 Wisniewski, 1985, Occurrence of neuropathological changes and dementia of Alzheimer’s disease in Down’s syndrome, Ann Neurol, 17, 278, 10.1002/ana.410170310 Wavrant-De Vrièze, 1999, Genetic variability at the amyloid-[beta] precursor protein locus may contribute to the risk of late-onset Alzheimer’s disease, Neurosci Lett, 269, 67, 10.1016/S0304-3940(99)00417-6 Lott, 2005, Alzheimer disease and Down syndrome: factors in pathogenesis, Neurobiol Aging, 26, 383, 10.1016/j.neurobiolaging.2004.08.005 Lagasse, 2000, Purified hematopoietic stem cells can differentiate into hepatocytes in vivo, Nat Med, 6, 1229, 10.1038/81326 Brazelton, 2000, From marrow to brain: expression of neuronal phenotypes in adult mice, Science, 290, 1775, 10.1126/science.290.5497.1775 Mezey, 2000, Bone marrow: a possible alternative source of cells in the adult nervous system, Eur J Pharmacol, 405, 297, 10.1016/S0014-2999(00)00561-6 Kucia, 2006, Cells enriched in markers of neural tissue-committed stem cells reside in the bone marrow and are mobilized into the peripheral blood following stroke, Leukemia, 20, 18, 10.1038/sj.leu.2404011 Abd El-Salam, 2001, Assessment of markers of oxidative stress and antioxidant enzymes in Egyptian Down syndrome patients. Ekram Abdel Salam, ImanBdel-Meguid and SoheirKorraThe Gaz, Egypt Paed, 49, 271 Sinet, 1982, Metabolism of oxygen derivatives in Down’s syndrome, Ann N Y Acad Sci, 396, 83, 10.1111/j.1749-6632.1982.tb26845.x Tanji, 2000, Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease, J Am Soc Nephrol, 11, 1656, 10.1681/ASN.V1191656 Nakamura, 1998, Biological ages of adult men and women with Down’s syndrome and its changes with ageing, Mech Ageing Dev, 105, 89, 10.1016/S0047-6374(98)00081-5 Xia, 2009, A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease, Arch Neurol, 66, 190, 10.1001/archneurol.2008.565 Duda, 2007, A protocol for phenotypic detection and enumeration of circulating endothelial cells and circulating progenitor cells in human blood, Nat Protoc, 2, 805, 10.1038/nprot.2007.111 Wisniewski, 1985, Occurrence of neuropathological changes and dementia of Alzheimer’s disease in Down’s syndrome, Ann Neurol, 17, 278, 10.1002/ana.410170310 Hoeffer, 2007, The Down syndrome Critical Region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling, J Neurosci, 27, 10.1523/JNEUROSCI.3974-07.2007 Sakata, 1998, Immunohistochemical localization of different epitopes of advanced glycation end products in human atherosclerotic lesions, Atherosclerosis, 141, 61, 10.1016/S0021-9150(98)00149-X Odetti, 1998, Early glycoxidation damage in brains from Down’s syndrome, Biochem Biophys Res Commun, 243, 849, 10.1006/bbrc.1998.8186 Robakis, 1987, Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neuritic (senile) plaques of people with Alzheimer disease and Down syndrome, Lancet, 1, 384, 10.1016/S0140-6736(87)91754-5 Prasher, 2010, Plasma beta amyloid and duration of Alzheimer’s disease in adults with Down syndrome, Int J Geriatr Psychiatry, 25, 202, 10.1002/gps.2321 Schupf, 2007, Elevated plasma beta-amyloid peptide Abeta(42) levels, incident dementia, and mortality in Down syndrome, Arch Neurol, 64, 1007, 10.1001/archneur.64.7.1007 Rovelet-Lecrux, 2006, APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy, Nat Genet, 38, 24, 10.1038/ng1718 Wavrant, 1999, Genetic variability at the amyloid-[beta] precursor protein locus may contribute to the risk of late-onset Alzheimer’s disease, Neurosci Lett, 269, 67, 10.1016/S0304-3940(99)00417-6 Prasher, 2010, Plasma beta amyloid and duration of Alzheimer’s disease in adults with Down syndrome, Int J Geriatr Psychiatry, 25, 202, 10.1002/gps.2321 Schupf, 2007, Elevated plasma beta-amyloid peptide Abeta(42) levels, incident dementia, and mortality in Down syndrome, Arch Neurol, 64, 1007, 10.1001/archneur.64.7.1007 Rensink, 2003, Pathogenesis of cerebral amyloid angiopathy, Brain Res Brain Res Rev, 43, 207, 10.1016/j.brainresrev.2003.08.001 Weller, 2008, Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer’s disease, Brain Pathol, 18, 253, 10.1111/j.1750-3639.2008.00133.x Nagababu, 2009, Vascular endothelial barrier dysfunction mediated by amyloid-β proteins, J Alzheimers Dis, 17, 845, 10.3233/JAD-2009-1104 van Vliet, 2007, Blood–brain barrier leakage may lead to progression of temporal lobe epilepsy, Brain, 130, 521, 10.1093/brain/awl318 Jablonska, 2006, The growth capacity of bone marrow CD34 positive cells in culture is drastically reduced in a murine model of Down syndrome, C R Biol, 329, 726, 10.1016/j.crvi.2006.06.004 Iwasaki, 2006, Dose-dependent contribution of CD34-positive cell transplantation to concurrent vasculogenesis and cardiomyogenesis for functional regenerative recovery after myocardial infarction, Circulation, 113, 1311, 10.1161/CIRCULATIONAHA.105.541268 Badorff, 2003, Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes, Circulation, 107, 1024, 10.1161/01.CIR.0000051460.85800.BB Hewitt, 2010, Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome, PLoS One, 5, e11561, 10.1371/journal.pone.0011561 Porayette, 2009, Differential processing of amyloid-β precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cells, J Biol Chem, 284, 23806, 10.1074/jbc.M109.026328 Whittle, 2007, Fetal Down syndrome brains exhibit aberrant levels of neurotransmitters critical for normal brain development, APPNEWS, Paediatrics, 120, 1465, 10.1542/peds.2006-3448 Wisniewski, 1990, Down syndrome children often have brain with maturation delay, retardation of growth, and cortical dysgenesis, Am J Med Genet Suppl, 37, 274 Golden, 1994, Development of the superior temporal neocortex is anomalous in trisomy 21, J Neuropathol Exp Neurol, 53, 513, 10.1097/00005072-199409000-00011 Wisniewski, 1984, Evidence of arrest of neurogenesis and synaptogenesis in brains of patients with Down’s syndrome, N Engl J Med, 311, 1187, 10.1056/NEJM198411013111819