Drug Research
SCOPUS (1972,2013-2025)ESCI-ISI
2194-9379
2194-9387
Đức
Cơ quản chủ quản: GEORG THIEME VERLAG KG , Thieme
Lĩnh vực:
Drug DiscoveryMedicine (miscellaneous)
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Strategies in Development and Delivery of Nanotechnology Based Cosmetic Products
Tập 68 Số 10 - Trang 545-552 - 2018
AbstractThe science of formulation involving cosmetic ingredients has always
been a challenge since the release of active components greatly depends upon the
carrier system involved and the selectivity of skin barrier. The principle
obstacle of the skin resides in the epidermis and it’s hard for many active
components to cross it. The formulation related factors like size of particles,
viscosity a...
Chrysin Alters microRNAs Expression Levels in Gastric Cancer Cells: Possible Molecular Mechanism
Tập 67 Số 09 - Trang 509-514 - 2017
Abstract Background Gastric carcinoma still remains the second most common cause
of cancer mortality in the world. Chrysin, as a flavone, has showed cancer
chemopreventive activity. The cellular and molecular mechanisms of chrysin in
cancer cells have not been fully understood. Objective In this study, we
investigate expression levels of let-7a, miR-9, mir-18a, miR-21, miR-22,
miR-34a, miR-126 and...
Antidiabetic Potentials of Citrus aurantifolia Leaf Essential Oil
Tập 69 Số 04 - Trang 201-206 - 2019
Abstract Citrus aurantifolia leaf essential oil was extracted via
hydrodistillation, chemical composition of the oil was analyzed using gas
chromatography-mass spectrometry and its antidiabetic potentials was assessed in
alloxan-induced hyperglycaemic rats using metformin as the reference drug for
comparison. Chemical analysis showed that D-limonene (57.84%) was the major
constituent of the oil. O...
Development of Multiple-Unit Floating Drug Delivery System of Clarithromycin: Formulation, in vitro Dissolution by Modified Dissolution Apparatus, in vivo Radiographic Studies in Human Volunteers
Tập 67 Số 07 - Trang 412-418 - 2017
AbstractClarithromycin (CM), a broad spectrum macrolide antibiotic used to
eradicate H. pylori in peptic ulcer. Clarithromycin (CM) is well absorbed from
the gastrointestinal tract, but has a bioavailability of 50% due to rapid
biodegradation. The aim of this investigation was to increase the gastric
residence time, and to control the drug release of clarithromycin by formulating
into multiple uni...
A Cautious Note on Thalidomide Usage in Cancer Treatment: Genetic Profiling of the TBX2 Sub-Family Gene Expression is Required
Tập 69 Số 09 - Trang 512-518 - 2019
AbstractThalidomide is still by excellence the mysterious drug that fascinated,
blurred, misled, and changed the scientific community perspectives and policies.
It was introduced in the 1950’s as a sedative drug, then shortly withdrawn
because of the devastating birth defects that affected tens of thousands
throughout more than 40 countries. Back into the market in the mid 1990’s and
2000’s the dr...