Drug Research
SCOPUS (1972,2013-2023)ESCI-ISI
2194-9379
2194-9387
Đức
Cơ quản chủ quản: GEORG THIEME VERLAG KG , Thieme
Lĩnh vực:
Drug DiscoveryMedicine (miscellaneous)
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Strategies in Development and Delivery of Nanotechnology Based Cosmetic ProductsAbstract The science of formulation involving cosmetic ingredients has always been a challenge since the release of active components greatly depends upon the carrier system involved and the selectivity of skin barrier. The principle obstacle of the skin resides in the epidermis and it’s hard for many active components to cross it. The formulation related factors li... ...
Tập 68 Số 10 - Trang 545-552 - 2018
Chrysin Alters microRNAs Expression Levels in Gastric Cancer Cells: Possible Molecular MechanismAbstract
Background Gastric carcinoma still remains the second most common cause of cancer mortality in the world. Chrysin, as a flavone, has showed cancer chemopreventive activity. The cellular and molecular mechanisms of chrysin in cancer cells have not been fully understood.
Objective In this study, we investigate expression levels of let-7a, mi... ...
Tập 67 Số 09 - Trang 509-514 - 2017
Antidiabetic Potentials of Citrus aurantifolia Leaf Essential OilAbstract
Citrus aurantifolia leaf essential oil was extracted via hydrodistillation, chemical composition of the oil was analyzed using gas chromatography-mass spectrometry and its antidiabetic potentials was assessed in alloxan-induced hyperglycaemic rats using metformin as the reference drug for comparison. Chemical analysis showed that D-limonene (57.84%) was th... ...
Tập 69 Số 04 - Trang 201-206 - 2019
Development of Multiple-Unit Floating Drug Delivery System of Clarithromycin: Formulation, in vitro Dissolution by Modified Dissolution Apparatus, in vivo Radiographic Studies in Human VolunteersAbstract Clarithromycin (CM), a broad spectrum macrolide antibiotic used to eradicate H. pylori in peptic ulcer. Clarithromycin (CM) is well absorbed from the gastrointestinal tract, but has a bioavailability of 50% due to rapid biodegradation. The aim of this investigation was to increase the gastric residence time, and to control the drug release of clarithromycin... ...
Tập 67 Số 07 - Trang 412-418 - 2017
A Cautious Note on Thalidomide Usage in Cancer Treatment: Genetic Profiling of the TBX2 Sub-Family Gene Expression is RequiredAbstract Thalidomide is still by excellence the mysterious drug that fascinated, blurred, misled, and changed the scientific community perspectives and policies. It was introduced in the 1950’s as a sedative drug, then shortly withdrawn because of the devastating birth defects that affected tens of thousands throughout more than 40 countries. Back into the market in... ...
Tập 69 Số 09 - Trang 512-518 - 2019