Usama Ahmad1, Zeeshan Ahmad1, Ahmed Shehab Khan1, Juber Akhtar1, Satya P. Singh1, Farhan Jalees Ahmad2
1Department of Pharmaceutics, Faculty of Pharmacy, Integral University, Lucknow, India
2Department of Pharmaceutics, Jamia Hamdard, New Delhi, India
Tóm tắt
AbstractThe science of formulation involving cosmetic ingredients has always been a challenge since the release of active components greatly depends upon the carrier system involved and the selectivity of skin barrier. The principle obstacle of the skin resides in the epidermis and it’s hard for many active components to cross it. The formulation related factors like size of particles, viscosity and lipophilicity of the components also play an important role in permeation of the dermal composition. Though widely used; conventional creams and gels still struggle in terms of success. This work focuses on nano based formulation strategies for successful delivery of cosmetic agents. Novel strategies like nanoemulsion, nanogels, liposomes, aquasomes, niosomes, dendrimers and fullerenes have paved way for successful delivery of dermal formulations to desire depths in the skin.