Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring Tập 7 Số 1 - 2012
Anthony E. Rizzardi, Arthur T. Johnson, Rachel I. Vogel, Stefan E. Pambuccian, Jonathan C. Henriksen, Amy P.N. Skubitz, Gregory J. Metzger, Stephen C. Schmechel
Abstract Abstract Immunohistochemical (IHC) assays performed on formalin-fixed
paraffin-embedded (FFPE) tissue sections traditionally have been semi-quantified
by pathologist visual scoring of staining. IHC is useful for validating
biomarkers discovered through genomics methods as large clinical repositories of
FFPE specimens support the construction of tissue microarrays (TMAs) for high
throughpu... hiện toàn bộ
Epithelioid Hemangioendothelioma: clinicopathologic, immunhistochemical, and molecular genetic analysis of 39 cases - 2014
Uta Flucke, Rob Vogels, Nicolas de Saint Aubain Somerhausen, David Creytens, Robert G. Riedl, Joost M. van Gorp, Anya N. Milne, Clément J.R. Huysentruyt, Marian A. J. Verdijk, Monique M. van Asseldonk, Albert Suurmeijer, Johannes Bras, Gabriele Palmedo, Patricia J.T.A. Groenen, Thomas Mentzel
Subtype distribution of lymphomas in Southwest China: Analysis of 6,382 cases using WHO classification in a single institution - 2011
Qinbo Yang, Wenyan Zhang, Jianbo Yu, Sha Zhao, Huan Xu, Wei-Ya Wang, Chengfeng Bi, Zhuo Zuo, Xiaoqing Wang, Juan Huang, Dong Lin, Weiping Liu
Abstract Background The subtype distribution of lymphoid neoplasms in Southwest
China was analyzed according to WHO classifications. This study aims to analyze
subtype distribution of lymphomas in southwest China. Methods Lymphoid neoplasms
diagnosed within 9 years in a single institution in Southwest China were
analyzed according to the WHO classification. Results From January 2000 to
December 20... hiện toàn bộ
Quantitative image analysis of immunohistochemical stains using a CMYK color model Tập 2 Số 1 - 2007
Nhu-An Pham, Andrew Morrison, Joerg Schwock, Sarit Aviel‐Ronen, Vladimir V. Iakovlev, Ming‐Sound Tsao, J. C. Ho, David Hedley
AbstractBackgroundComputer image analysis techniques have decreased effects of
observer biases, and increased the sensitivity and the throughput of
immunohistochemistry (IHC) as a tissue-based procedure for the evaluation of
diseases.MethodsWe adapted a Cyan/Magenta/Yellow/Key (CMYK) model for automated
computer image analysis to quantify IHC stains in hematoxylin counterstained
histological secti... hiện toàn bộ
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19) – anatomic pathology perspective on current knowledge Tập 15 Số 1 - 2020
Sambit K. Mohanty, Abhishek Satapathy, Machita M. Naidu, Sanjay Mukhopadhyay, Shruti Sharma, Lisa M. Barton, Edana Stroberg, Eric J. Duval, Dinesh Pradhan, Alexandar Tzankov, Anil V. Parwani
AbstractBackgroundThe world is currently witnessing a major devastating pandemic
of Coronavirus disease-2019 (COVID-19). This disease is caused by a novel
coronavirus named Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).
It primarily affects the respiratory tract and particularly the lungs. The virus
enters the cell by attaching its spike-like surface projections to the
angiotensin-c... hiện toàn bộ