Diabetology & Metabolic Syndrome

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Association of HSD11B1 polymorphic variants and adipose tissue gene expression with metabolic syndrome, obesity and type 2 diabetes mellitus: a systematic review
Diabetology & Metabolic Syndrome - Tập 7 - Trang 1-13 - 2015
Filipe Valvassori do Nascimento, Vanessa Piccoli, Mayara Abichequer Beer, Anize Delfino von Frankenberg, Daisy Crispim, Fernando Gerchman
The HSD11B1 gene is highly expressed in abdominal adipose tissue, and the enzyme it encodes catalyzes the interconversion of inactive cortisone to hormonally active cortisol. Genetic abnormalities of HSD11B1 have been associated with the development of abnormal glucose metabolism and body fat distribution. To systematically review studies evaluating the association of HSD11B1 gene expression in ab... hiện toàn bộ
Lipidomic analysis of human plasma reveals ether-linked lipids that are elevated in morbidly obese humans compared to lean
Diabetology & Metabolic Syndrome - Tập 5 - Trang 1-13 - 2013
Elise L Donovan, Stefan M Pettine, Matthew S Hickey, Karyn L Hamilton, Benjamin F Miller
Lipidomic analysis was performed to explore differences in lipid profiles between plasma from lean and obese subjects, followed by in vitro methods to examine a role for the identified lipids in endothelial cell pathophysiology. Plasma was collected from 15 morbidly obese and 13 control subjects. Lipids were extracted from plasma and analyzed using LC/MS, and MS/MS to characterize lipid profiles a... hiện toàn bộ
Current views on selenoprotein S in the pathophysiological processes of diabetes-induced atherosclerosis: potential therapeutics and underlying biomarkers
Diabetology & Metabolic Syndrome - Tập 16 - Trang 1-13 - 2024
Shan-shan Yu, Jian-ling Du
Atherosclerotic cardiovascular disease (ASCVD) consistently ranks as the primary mortality factor among diabetic people. A thorough comprehension of the pathophysiological routes and processes activated by atherosclerosis (AS) caused by diabetes mellitus (DM), together with the recognition of new contributing factors, could lead to the discovery of crucial biomarkers and the development of innovat... hiện toàn bộ
High prevalence of Berardinelli-Seip Congenital Lipodystrophy in Rio Grande do Norte State, Northeast Brazil
Diabetology & Metabolic Syndrome - - 2017
Lázaro Batista de Azevedo Medeiros, Verônica Kristina Cândido Dantas, Aquiles Sales Craveiro Sarmento, Lucymara Fassarella Agnez-Lima, Adriana Lúcia Meireles, Thaíza Teixeira Xavier Nobre, Josivan Gomes Lima, Julliane Tamara Araújo de Melo Campos
Impact of diabetes mellitus developing after kidney transplantation on patient mortality and graft survival: a meta-analysis of adjusted data
Diabetology & Metabolic Syndrome - Tập 13 - Trang 1-11 - 2021
Hailing Lin, Jiqiang Yan, Lei Yuan, Beibei Qi, Zhujing Zhang, Wanlu Zhang, Aihua Ma, Fuwan Ding
Post-transplant diabetes mellitus (PTDM) occurs in 10–30% of kidney transplant recipients. However, its impact on mortality and graft survival is still ambiguous. Therefore, the current study aimed to analyze if PTDM increases mortality and graft failure by pooling multivariable-adjusted data from individual studies. PubMed, Embase, and CENTRAL, and Google Scholar were searched for studies compari... hiện toàn bộ
The prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of Jordan
Diabetology & Metabolic Syndrome - - 2018
Nahla Khawaja, Jawad Ahmad Abu-Shennar, Mohammad Saleh, Said Dahbour, Yousef Khader, Kamel Ajlouni
The polygenetically inherited metabolic syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue
Diabetology & Metabolic Syndrome - Tập 5 - Trang 1-8 - 2013
Joanna Kosacka, Karoline Koch, Martin Gericke, Marcin Nowicki, John T Heiker, Ingrid Klöting, Michael Stumvoll, Matthias Blüher, Nora Klöting
Recent studies revealed that autophagy is up-regulated in obese individuals, as evidenced by increased expression of autophagy related genes. As argued elsewhere, it is possible that initially insulin resistance functions as an adaptive mechanism to increase autophagy in order to protect cells against death. We have shown that Wistar Ottawa Karlsburg W (RT1u) rats (WOKW) develop a metabolic syndro... hiện toàn bộ
Correcting calculation and data errors reveals that the original conclusions were incorrect in “The best drug supplement for obesity treatment: a systematic review and network meta-analysis”
Diabetology & Metabolic Syndrome - Tập 15 Số 1
Xuewen Yu, Patrice L. Capers, Roger S. Zoh, David B. Allison
AbstractThe goal of this study was to reproduce and evaluate the reliability of the network meta-analysis performed in the article “The best drug supplement for obesity treatment: A systematic review and network meta-analysis” by Salari et al. In recent years, it has become more common to employ network meta-analysis to assess the relative efficacy of treatments often used in clinical practice. To... hiện toàn bộ
Relationship between Dietary and Other Lifestyle Habits and Cardiometabolic Risk Factors in Men
Diabetology & Metabolic Syndrome - - 2011
Sayuri Katano, Yasuyuki Nakamura, Nagako Okuda, Yoshitaka Murakami, Nagako Chiba, Katsushi Yoshita, Tsunehiko Tanaka, Junko Tamaki, Toru Takebayashi, Akira Okayama, Katsuyuki Miura, Tomonori Okamura, Hirotsugu Ueshima
Abstract Background Prevalence of men with cardiometabolic risk factors (CMRF) is increasing in Japan. Few studies have comprehensively examined the relation between lifestyles and CMRF. Methods We examined the baseline data from 3,498 male workers ages 19 to 69 years who participated in the high-risk and population strategy for occupational health promotion (HIPOP-OHP) study at 12 large-scale com... hiện toàn bộ
Consensus recommendations for management of patients with type 2 diabetes mellitus and cardiovascular diseases
Diabetology & Metabolic Syndrome - - 2019
Alaaeldin Bashier, Azza Bin Hussain, Elamin Abdelgadir, Fatheya Alawadi, Hani Sabbour, Robert Chilton
The recent American Diabetes Association and the European Association for the Study of Diabetes guideline mentioned glycaemia management in type 2 diabetes mellitus (T2DM) patients with cardiovascular diseases (CVDs); however, it did not cover the treatment approaches for patients with T2DM having a high risk of CVD, and treatment and screening approaches for CVDs in patients with concomitant T2DM... hiện toàn bộ
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