Lipidomic analysis of human plasma reveals ether-linked lipids that are elevated in morbidly obese humans compared to leanDiabetology & Metabolic Syndrome - Tập 5 - Trang 1-13 - 2013
Elise L Donovan, Stefan M Pettine, Matthew S Hickey, Karyn L Hamilton, Benjamin F Miller
Lipidomic analysis was performed to explore differences in lipid profiles between plasma from lean and obese subjects, followed by in vitro methods to examine a role for the identified lipids in endothelial cell pathophysiology. Plasma was collected from 15 morbidly obese and 13 control subjects. Lipids were extracted from plasma and analyzed using LC/MS, and MS/MS to characterize lipid profiles a...... hiện toàn bộ
Impact of diabetes mellitus developing after kidney transplantation on patient mortality and graft survival: a meta-analysis of adjusted dataDiabetology & Metabolic Syndrome - Tập 13 - Trang 1-11 - 2021
Hailing Lin, Jiqiang Yan, Lei Yuan, Beibei Qi, Zhujing Zhang, Wanlu Zhang, Aihua Ma, Fuwan Ding
Post-transplant diabetes mellitus (PTDM) occurs in 10–30% of kidney transplant recipients. However, its impact on mortality and graft survival is still ambiguous. Therefore, the current study aimed to analyze if PTDM increases mortality and graft failure by pooling multivariable-adjusted data from individual studies. PubMed, Embase, and CENTRAL, and Google Scholar were searched for studies compari...... hiện toàn bộ
The polygenetically inherited metabolic syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissueDiabetology & Metabolic Syndrome - Tập 5 - Trang 1-8 - 2013
Joanna Kosacka, Karoline Koch, Martin Gericke, Marcin Nowicki, John T Heiker, Ingrid Klöting, Michael Stumvoll, Matthias Blüher, Nora Klöting
Recent studies revealed that autophagy is up-regulated in obese individuals, as evidenced by increased expression of autophagy related genes. As argued elsewhere, it is possible that initially insulin resistance functions as an adaptive mechanism to increase autophagy in order to protect cells against death. We have shown that Wistar Ottawa Karlsburg W (RT1u) rats (WOKW) develop a metabolic syndro...... hiện toàn bộ
LEADER 7: cardiovascular risk profiles of US and European participants in the LEADER diabetes trial differDiabetology & Metabolic Syndrome - Tập 8 - Trang 1-9 - 2016
Guy E. H. M. Rutten, Cees J. Tack, Thomas R. Pieber, Abdurrahman Comlekci, David Dynnes Ørsted, Florian M. M. Baeres, Steven P. Marso, John B. Buse
To determine whether US and European participants in the Liraglutide Effect and Action in Diabetes: Evaluation of cardiovascular outcome Results (LEADER) trial differ regarding risk factors for cardiovascular mortality and morbidity. Baseline data, stratified for prior cardiovascular disease (CVD), were compared using multivariable logistic regression analysis to establish whether region is an ind...... hiện toàn bộ
Streptozotocin-induced diabetes disrupts the body temperature daily rhythm in ratsDiabetology & Metabolic Syndrome - Tập 7 - Trang 1-13 - 2015
Angela M Ramos-Lobo, Daniella C Buonfiglio, José Cipolla-Neto
In mammals, the temperature rhythm is regulated by the circadian pacemaker located in the suprachiasmatic nuclei, and is considered a “marker rhythm”. Melatonin, the pineal gland hormone, is a major regulator of the endogenous rhythms including body temperature. Its production is influenced by many factors, such as type 1 diabetes mellitus. In rats, diabetes leads to hypothermia and reduced melato...... hiện toàn bộ
The prevalence of metabolic syndrome in cardiovascular patients in Iran: a systematic review and meta-analysisDiabetology & Metabolic Syndrome - - 2020
Nader Salari, Peyman Kaikhosro Doulatyari, Alireza Daneshkhah, Aliakbar Vaisi-Raygani, Rostam Jalali, Parnian kord Jamshidi, Alireza Abdi, Masoud Mohammadi, Mohsen Kazeminia
Cardiovascular disease is the cause of more than 50% of mortalities globally, and this rate has grown by 8.6% since the 60 s. One of the risk factors associated with cardiovascular disease and its resulting mortality rate is the metabolic syndrome. Different studies have reported inconsistent rates for the metabolic syndrome. However, no comprehensive study has been conducted to combine the result...... hiện toàn bộ