Dementia and Geriatric Cognitive Disorders
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French-English Cross-Linguistic Comparison and Diagnostic Impact of the AD-8 Dementia Screening Questionnaire in a Geriatric Assessment Clinic
Dementia and Geriatric Cognitive Disorders - Tập 29 Số 3 - Trang 265-274 - 2010
The AD-8 dementia screening questionnaire is a novel tool that allows clinicians
to assess changes in cognitive function. This study examined psychometric
properties of the test in French-speaking and English-speaking patients, and its
impact on diagnostic practice in the geriatric assessment clinics of a
university health centre. Data were extracted from the clinical database for all
new patients...
Prevalence of Alzheimer’s Disease and Other Dementing Disorders: Assiut-Upper Egypt Study
Dementia and Geriatric Cognitive Disorders - Tập 9 Số 6 - Trang 323-328 - 1998
The aim of this study was to determine the prevalence rate of Alzheimer’s
disease (AD) and other types of dementias among the population over the age of
60 years in Assiut governorate. A 3-phase cross-sectional population-based study
was carried out to screen 2,000 subjects residing in 11 different locations
representing the sociocultural status of the area. We subjected each proband to
a modified...
Atrophy of Hippocampal Formation Subdivisions Correlates with Stage and Duration of Alzheimer Disease
Dementia and Geriatric Cognitive Disorders - Tập 6 Số 4 - Trang 205-210 - 1995
The hippocampal formations of 13 subjects with severe Alzheimer disease [AD;
Global Deterioration Scale (GDS) stage 7] and of 5 age-matched subjects without
symptoms of dementia were reconstructed from serial sections. Functional
assessment staging (FAST) was used at the time of demise to assess 9 patients at
stages 7a–c (incipient averbal and nonambulatory) and 4 patients at stages 7e–f
(immobile...
Subjective Memory Complaints: Presence, Severity and Future Outcome in Normal Older Subjects
Dementia and Geriatric Cognitive Disorders - Tập 24 Số 3 - Trang 177-184 - 2007
Background/Aims: Subjective memory complaint (SMC) in normal individuals
may predict future cognitive decline. The goal of this study was to examine
whether the probability of decline increases with growing intensity of
complaint. Methods: Normal subjects over the age of 50 years were
included in a longitudinal retrospective study (mean follow-up time = 8 years).
All subjects (n = 23...
Association between BDNF Polymorphism (Val66Met) and Executive Function in Patients with Amnestic Mild Cognitive Impairment or Mild Alzheimer Disease
Dementia and Geriatric Cognitive Disorders - Tập 33 Số 4 - Trang 266-272 - 2012
Functional Magnetic Resonance Imaging of Compensatory Neural Recruitment in Aging and Risk for Alzheimer’s Disease: Review and Recommendations
Dementia and Geriatric Cognitive Disorders - Tập 27 Số 1 - Trang 1-10 - 2009
There has been a recent proliferation of functional magnetic resonance imaging
(fMRI) studies that interpret between-group or within-group differences in brain
response patterns as evidence for compensatory neural recruitment. However, it
is currently a challenge to determine whether these observed differences are
truly attributable to compensatory neural recruitment or whether they are
indicative...
Improvement of Episodic Memory in Persons with Mild Cognitive Impairment and Healthy Older Adults: Evidence from a Cognitive Intervention Program
Dementia and Geriatric Cognitive Disorders - Tập 22 Số 5-6 - Trang 486-499 - 2006
The efficacy of cognitive training was assessed in persons with mild cognitive
impairment (MCI) and persons with normal cognitive aging. Forty-seven
participants were included in this study: 28 with MCI and 17 controls.
Twenty-one participants received intervention (20 MCI and 9 controls) and 16
participants (8 MCI and 8 controls) received no intervention (waiting-list
group). The intervention foc...
Clock Drawing Test in Mild Cognitive Impairment: Quantitative Analysis of Four Scoring Methods and Qualitative Analysis
Dementia and Geriatric Cognitive Disorders - Tập 26 Số 6 - Trang 483-489 - 2008
Background: The role of the clock drawing test (CDT) as a screening tool
for dementia has been evaluated. However, studies focusing on mild cognitive
impairment (MCI) are still lacking. The purpose of this study was to verify the
validity of the CDT as a screening method for MCI. Methods: 524 subjects
aged 60 years and older were recruited in the community. Of these, 241 were
diagnos...
Distinctive Clinical Features of Mild Cognitive Impairment with Subcortical Cerebrovascular Disease
Dementia and Geriatric Cognitive Disorders - Tập 19 Số 4 - Trang 196-203 - 2005
Background and Purpose: Patients with mild cognitive impairment and
subcortical cerebrovascular disease (svMCI) can be isolated using criteria
modified from those of Erkinjuntti et al. for subcortical vascular dementia and
have poorer outcomes (cognitive deterioration, disability, institutionalization,
and mortality). The aim of this study was to test which of the core
(dysexecutive syndrom...
Dominant Frontotemporal Dementia Mutations in 140 Cases of Primary Progressive Aphasia and Speech Apraxia
Dementia and Geriatric Cognitive Disorders - Tập 39 Số 5-6 - Trang 281-286 - 2015
Background: Mutations in three genes [chromosome 9
open-reading-frame 72 (C9ORF72); microtubule-associated protein tau
(MAPT) and progranulin (GRN)] account for the vast majority of
familial, and a proportion of sporadic, frontotemporal dementia (FTD) cases.
Progressive apraxia of speech (PAOS) is a type of FTD characterized by speech
production deficits without ...
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