Cytogenetic and Genome Research
SCOPUS (1962-1975,1989,1991-1992,1994,1996-1997,2002-2023)SCIE-ISI
1424-8581
1424-859X
Thụy Sĩ
Cơ quản chủ quản: KARGER , S. Karger AG
Lĩnh vực:
Genetics (clinical)GeneticsMolecular Biology
Các bài báo tiêu biểu
An Air-Drying Method for Chromosome Preparations from Mouse EggsThe eggs, after being washed out from the genital tract, are put into hypotonic (1%) sodium citrate and left to stand at room temperature for 5–15 minutes. The duration of treatment is not very critical, but later stages, especially blastocysts, need longer treatment. A microdrop of this solution together with the eggs is placed on a grease-free slide. A few drops of acetic alcohol (3 part... ... hiện toàn bộ
Tập 5 Số 6 - Trang 394-400 - 1966
An Air-Drying Method for Meiotic Preparations from Mammalian TestesA suspension is made in isotonic (2.2%) sodium citrate solution from the contents of the tubules from a whole testis or a testicular biopsy specimen. The germinal cells are sedimented by centrifuging, leaving most of the sperm in the supernatant fluid, which is discarded. The cells are resuspended in hypo-tonic (1%) sodium citrate solution and left to stand at room temperature for 12 minut... ... hiện toàn bộ
Tập 3 Số 5 - Trang 289-294 - 1964
Yeast stimulation of bone marrow mitosis for cytogenetic investigationsWe report a simple, dependable method for stimulating bone marrow mitosis in small mammals. Subcutaneous injections of a suspension of active baker’s yeast may elevate the mitotic index as much as six times or more. Additionally, the metaphases obtained are easily spread when air dried, and the chromosomes are readily banded. This method should prove useful to investigators who wish to use... ... hiện toàn bộ
Tập 26 Số 1 - Trang 36-40 - 1980
Stress activation and genomic impact of Tnt1 retrotransposons in SolanaceaeTnt1 elements are a superfamily of LTR-retrotransposons distributed in the Solanaceae plant family and represent good model systems for studying regulatory and evolutionary controls established between hosts and transposable elements. Tnt1 retrotransposons tightly control their activation, by restricting expression to specific conditions. The Tnt1A element, originally discovered in tobacco... ... hiện toàn bộ
Tập 110 Số 1-4 - Trang 229-241 - 2005
Digitized and differentially shaded human chromosome ideograms for genomic applicationsHuman chromosome ideograms that depict 850 bands, numbered in agreement with ISCN (1981) nomenclature but based on actual measurements of band sizes and differentiated by five shades of staining intensity, have been digitized using commercially available graphics software. They provide for more accurate estimates of distances within chromosome arms, DNA content of chromosome bands and corr... ... hiện toàn bộ
Tập 65 Số 3 - Trang 206-219 - 1994
Isolation, characterization and mapping of the mouse and human PRG4 (proteoglycan 4) genesPRG4 (proteoglycan 4) has been identified as megakaryocyte stimulating factor and articular superficial zone protein. PRG4 has characteristic motifs including somatomedin B and hemopexin domains, a chondroitin sulfate-attachment site and mucin-like repeats. During a screen of genes implicated in ectopic ossification, we found a novel mouse gene highly homologous to human and bovine PRG4 ge... ... hiện toàn bộ
Tập 90 Số 3-4 - Trang 291-297 - 2000
A simplified technique for in vivo analysis of sister-chromatid exchanges using 5-bromodeoxyuridine tabletsA small tablet of 5-bromodeoxyuridine (BrdU), implanted subcutaneously in a mouse, provides sustained release of base analog sufficient to effect substitution of DNA throughout an entire replication period. As illustrated by studies of mouse bone-marrow and spleen cells in the presence or absence of cyclophosphamide, this depot method of BrdU administration greatly simplifies in vivo analy... ... hiện toàn bộ
Tập 18 Số 4 - Trang 231-237 - 1977
Report of the committee on chromosome and gene loss in human neoplasia
Tập 58 Số 3-4 - Trang 1080-1096 - 1991
Meningioma: a cytogenetic model of a complex benign human tumor, including data on 394 karyotyped casesMeningioma is the most frequent tumor of neuroectodermal origin in humans. It is usually benign. Only a minority of cases shows progression to an anaplastic tumor (WHO grade II and III). Meningioma is generally a sporadic tumor. Multiple and familial cases are rare and mostly associated with (hereditary) neurofibromatosis 2 (NF2). Meningiomas show an unexpectedly high recurrence rate. Also... ... hiện toàn bộ
Tập 93 Số 3-4 - Trang 207-220 - 2001