Neuro-toxic and Reproductive Effects of BPACurrent Neuropharmacology - Tập 17 Số 12 - Trang 1109-1132 - 2019
Antonietta Santoro, Rosanna Chianese, Jacopo Troisi, Sean Richards, Stefania Lucia Nori, Silvia Fasano, Maurizio Guida, Elizabeth Plunk, Andrea Viggiano, Riccardo Pierantoni, Rosaria Meccariello
Background:Bisphenol A (BPA) is one of the highest volume chemicals produced worldwide. It has recognized activity as an endocrine-disrupting chemical and has suspected roles as a neurological and reproductive toxicant. It interferes in steroid signaling, induces oxidative stress, and affects gene expression epigenetically. Gestational, perinatal and neon...... hiện toàn bộ
Animal Galectins and Plant Lectins as Tools for Studies in NeurosciencesCurrent Neuropharmacology - Tập 18 Số 3 - Trang 202-215 - 2020
João Ronielly Campêlo Araújo, Cauê Barbosa Coelho, Adriana Rolim Campos, Renato de Azevedo Moreira, Ana Cristina de Oliveira Monteiro‐Moreira
Lectins are proteins or glycoproteins of non-immunological origin capable of reversibly and specifically binding to glycoconjugates. They exist in free form or associated with cells and are widely distributed in nature, being found in plants, microorganisms, and animals. Due to their characteristics and mainly due to the possibility of reversible binding to glycocon...... hiện toàn bộ
Neuroinflammation in Huntington’s Disease: A Starring Role for Astrocyte and MicrogliaCurrent Neuropharmacology - Tập 20 Số 6 - Trang 1116-1143 - 2022
Julieta Saba, Federico López Couselo, Julieta Bruno, Lila Carniglia, Daniela Durand, Mercedes Lasaga, Carla Caruso
:
Huntington’s disease (HD) is a neurodegenerative genetic disorder caused by a CAG repeat
expansion in the huntingtin gene. HD causes motor, cognitive, and behavioral dysfunction.
Since no existing treatment affects the course of this disease, new treatments are needed. Inflammation
is frequently observed in HD patients before symptom onset. Neuroinflam...... hiện toàn bộ