Comparative and Functional Genomics
1531-6912
1532-6268
Cơ quản chủ quản: N/A
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Các bài báo tiêu biểu
A system for identifying named entities in biomedical text: how results from two evaluations reflect on both the system and the evaluations
Tập 6 Số 1‐2 - Trang 77-85 - 2005
Abstract We present a maximum entropy‐based system for identifying named entities (NEs) in biomedical abstracts and present its performance in the only two biomedical named entity recognition (NER) comparative evaluations that have been held to date, namely BioCreative and Coling BioNLP. Our system obtained an exact match F‐score of 83.2% in the BioCreative evaluation and 70.1% in the BioNLP evalu...... hiện toàn bộ
#automatic named entity recognition #manual annotation of biomedical texts
A system for identifying named entities in biomedical text: how results from two evaluations reflect on both the system and the evaluationsAbstract We present a maximum entropy‐based system for identifying named entities (NEs) in biomedical abstracts and present its performance in the only two biomedical named entity recognition (NER) comparative evaluations that have been held to date, namely BioCreative and Coling BioNLP. Our system obtained an exact match F‐score of 83.2% in the BioCreative evaluati... ... hiện toàn bộ
Tập 6 Số 1-2 - Trang 77-85 - 2005
Why chloroplasts and mitochondria contain genomesAbstract Chloroplasts and mitochondria originated as bacterial symbionts. The larger, host cells acquired genetic information from their prokaryotic guests by lateral gene transfer. The prokaryotically‐derived genes of the eukaryotic cell nucleus now function to encode the great majority of chloroplast and mitochondrial proteins, as well as many proteins of the nucl... ... hiện toàn bộ
Tập 4 Số 1 - Trang 31-36 - 2003
Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAsThe composition of the cellular proteome is under the control of multiple processes, one of the most important being translation initiation. The majority of eukaryotic cellular mRNAs initiates translation by the cap-dependent or scanning mode of translation initiation, a mechanism that depends on the recognition of the m7 G(5′ )ppp(5′... hiện toàn bộ
Tập 2012 - Trang 1-12 - 2012
Comparative Analysis of CpG Islands in Four Fish GenomesThere has been much interest in CpG islands (CGIs), clusters of CpG dinucleotides in GC-rich regions, because they are considered gene markers and involved in gene regulation. To date, there has been no genome-wide analysis of CGIs in the fish genome. We first evaluated the performance of three popular CGI identification algorithms in four fish genomes (tetraodon, stickleback, medaka, and ... ... hiện toàn bộ
Tập 2008 - Trang 1-6 - 2008
Regulation of Translation Initiation under Abiotic Stress Conditions in Plants: Is It a Conserved or Not so Conserved Process among Eukaryotes?For years, the study of gene expression regulation of plants in response to stress conditions has been focused mainly on the analysis of transcriptional changes. However, the knowledge on translational regulation is very scarce in these organisms, despite in plants, as in the rest of the eukaryotes, translational regulation has been proven to play a pivotal role in the response to differen... ... hiện toàn bộ
Tập 2012 - Trang 1-8 - 2012
Heterologous array analysis in Pinaceae: hybridization of Pinus taeda cDNA arrays with cDNA from needles and embryogenic cultures of P. taeda, P. sylvestris or Picea abiesAbstract Hybridization of labelled cDNA from various cell types with high‐density arrays of expressed sequence tags is a powerful technique for investigating gene expression. Few conifer cDNA libraries have been sequenced. Because of the high level of sequence conservation between Pinus and Picea we have investig... ... hiện toàn bộ
Tập 3 Số 4 - Trang 306-318 - 2002
A survey of nucleotide cyclases in Actinobacteria: unique domain organization and expansion of the class III cyclase family in Mycobacterium tuberculosisAbstract Cyclic nucleotides are well‐known second messengers involved in the regulation of important metabolic pathways or virulence factors. There are six different classes of nucleotide cyclases that can accomplish the task of generating cAMP, and four of these are restricted to the prokaryotes. The role of cAMP has been implicated in the virulence and regulation ... ... hiện toàn bộ
Tập 5 Số 1 - Trang 17-38 - 2004
Protein Coding Gene Nucleotide Substitution Pattern in the Apicomplexan ProtozoaCryptosporidium parvumandCryptosporidium hominisCryptosporidium parvum andC. hominis are related protozoan pathogens which infect the intestinal epithelium of humans and other vertebrates. To explore the evolution of these parasites, and identify genes under positive selection, we performed a pairwise whole-genome comparison between all orthologous protein coding genes inC...
Tập 2008 - Trang 1-6 - 2008