Comparative and Functional Genomics
SCOPUS (2000-2005,2007-2012)
1531-6912
1532-6268
Cơ quản chủ quản: N/A
Các bài báo tiêu biểu
Why chloroplasts and mitochondria contain genomes
Tập 4 Số 1 - Trang 31-36 - 2003
AbstractChloroplasts and mitochondria originated as bacterial symbionts. The
larger, host cells acquired genetic information from their prokaryotic guests by
lateral gene transfer. The prokaryotically‐derived genes of the eukaryotic cell
nucleus now function to encode the great majority of chloroplast and
mitochondrial proteins, as well as many proteins of the nucleus and cytosol.
Genes are copied...
Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAs
Tập 2012 - Trang 1-12 - 2012
The composition of the cellular proteome is under the control of multiple
processes, one of the most important being translation initiation. The majority
of eukaryotic cellular mRNAs initiates translation by the cap-dependent or
scanning mode of translation initiation, a mechanism that depends on the
recognition of the m7G(5′)ppp(5′)N, known as the cap. However, mRNAs encoding
proteins required fo...
Comparative Analysis of CpG Islands in Four Fish Genomes
Tập 2008 - Trang 1-6 - 2008
There has been much interest in CpG islands (CGIs), clusters of CpG
dinucleotides in GC-rich regions, because they are considered gene markers and
involved in gene regulation. To date, there has been no genome-wide analysis of
CGIs in the fish genome. We first evaluated the performance of three popular CGI
identification algorithms in four fish genomes (tetraodon, stickleback, medaka,
and zebrafis...
Regulation of Translation Initiation under Abiotic Stress Conditions in Plants: Is It a Conserved or Not so Conserved Process among Eukaryotes?
Tập 2012 - Trang 1-8 - 2012
For years, the study of gene expression regulation of plants in response to
stress conditions has been focused mainly on the analysis of transcriptional
changes. However, the knowledge on translational regulation is very scarce in
these organisms, despite in plants, as in the rest of the eukaryotes,
translational regulation has been proven to play a pivotal role in the response
to different stress...
Heterologous array analysis in Pinaceae: hybridization of Pinus taeda cDNA arrays with cDNA from needles and embryogenic cultures of P. taeda, P. sylvestris or Picea abies
Tập 3 Số 4 - Trang 306-318 - 2002
AbstractHybridization of labelled cDNA from various cell types with high‐density
arrays of expressed sequence tags is a powerful technique for investigating gene
expression. Few conifer cDNA libraries have been sequenced. Because of the high
level of sequence conservation between Pinus and Picea we have investigated the
use of arrays from one genus for studies of gene expression in the other. The
...
A survey of nucleotide cyclases in Actinobacteria: unique domain organization and expansion of the class III cyclase family in Mycobacterium tuberculosis
Tập 5 Số 1 - Trang 17-38 - 2004
AbstractCyclic nucleotides are well‐known second messengers involved in the
regulation of important metabolic pathways or virulence factors. There are six
different classes of nucleotide cyclases that can accomplish the task of
generating cAMP, and four of these are restricted to the prokaryotes. The role
of cAMP has been implicated in the virulence and regulation of secondary
metabolites in the p...
Protein Coding Gene Nucleotide Substitution Pattern in the Apicomplexan ProtozoaCryptosporidium parvumandCryptosporidium hominis
Tập 2008 - Trang 1-6 - 2008
Cryptosporidium parvumandC. hominisare related protozoan pathogens which infect
the intestinal epithelium of humans and other vertebrates. To explore the
evolution of these parasites, and identify genes under positive selection, we
performed a pairwise whole-genome comparison between all orthologous protein
coding genes inC. parvumandC. hominis. Genome-wide calculation of the ratio of
nonsynonymou...
A system for identifying named entities in biomedical text: how results from two evaluations reflect on both the system and the evaluations
Tập 6 Số 1‐2 - Trang 77-85 - 2005
Abstract We present a maximum entropy‐based system for identifying named
entities (NEs) in biomedical abstracts and present its performance in the only
two biomedical named entity recognition (NER) comparative evaluations that have
been held to date, namely BioCreative and Coling BioNLP. Our system obtained an
exact match F‐score of 83.2% in the BioCreative evaluation and 70.1% in the
BioNLP evalu...
#automatic named entity recognition #manual annotation of biomedical texts