Why chloroplasts and mitochondria contain genomes

Comparative and Functional Genomics - Tập 4 Số 1 - Trang 31-36 - 2003
John F. Allen1
1Plant Biochemistry, Center for Chemistry and Chemical Engineering, Lund University, Box 124, SE‐221 00 Lund, Sweden

Tóm tắt

AbstractChloroplasts and mitochondria originated as bacterial symbionts. The larger, host cells acquired genetic information from their prokaryotic guests by lateral gene transfer. The prokaryotically‐derived genes of the eukaryotic cell nucleus now function to encode the great majority of chloroplast and mitochondrial proteins, as well as many proteins of the nucleus and cytosol. Genes are copied and moved between cellular compartments with relative ease, and there is no established obstacle to successful import of any protein precursor from the cytosol. Yet chloroplasts and mitochondria have not abdicated all genes and gene expression to the nucleus and to cytosolic translation. What, then, do chloroplast‐ and mitochondrially‐encoded proteins have in common that confers a selective advantage on the cytoplasmic location of their genes? The proposal advanced here is that co‐location of chloroplast and mitochondrial genes with their gene products is required for rapid and direct regulatory coupling. Redox control of gene expression is suggested as the common feature of those chloroplast and mitochondrial proteins that are encoded in situ. Recent evidence is consistent with this hypothesis, and its underlying assumptions and predictions are described. Copyright © 2003 John Wiley & Sons, Ltd.

Từ khóa


Tài liệu tham khảo

10.1038/35042567

Alberts B, 1994, The Molecular Biology of the Cell

10.1080/13510002.1995.11746969

10.1006/jtbi.1993.1210

10.1007/BF00016274

10.1016/S0092-8674(02)00870-X

10.1098/rstb.2002.1191

10.1098/rstb.2000.0697

10.1007/BF02352278

10.1146/annurev.cb.04.110188.001445

10.1046/j.1365-2958.2000.01719.x

10.1126/science.1138359

10.1111/j.1432-1033.1995.0762m.x

10.1126/science.284.5423.2124

10.1038/24994

10.1016/S0968-0004(00)01684-4

10.1007/s002940050343

10.1146/annurev.cb.06.110190.001013

10.1038/35042663

10.1126/science.283.5407.1476

10.1016/S0168-9525(01)02312-5

10.1016/S0167-4889(01)00148-3

10.1016/S0968-0004(99)01462-0

Komiya T, 1997, Binding of mitochondrial precursor proteins to the cytoplasmic domains of the import receptors Tom70 and Tom20 is determined by cytoplasmic chaperones, FASEB J, 11, 1196

Konstantinov YM, 1995, Genetic functions of isolated maize mitochondria under model changes of redox conditions, Biochem Mol Biol Int, 36, 319

Lemire BD, 1989, The mitochondrial targeting function of randomly generated peptide sequences correlates with predicted helical amphiphilicity, J Biol Chem, 264, 20 206, 10.1016/S0021-9258(19)47048-8

10.1016/S0074-7696(08)60067-4

10.1098/rspb.1999.0792

10.1104/pp.118.1.9

10.1515/BC.2001.187

10.1038/30234

10.1126/science.275.5301.790

10.1111/j.1432-1033.1993.tb18389.x

10.1016/S0955-0674(02)00355-1

10.1038/17624

10.1080/713803507

10.1146/annurev.bb.19.060190.002101

10.1016/S0168-9525(99)01766-7

10.1111/j.1469-185X.1994.tb01486.x

10.1038/35073038

10.1016/S0378-1119(00)00484-4

10.1126/science.1061036

10.1007/s00203-002-0434-2

10.1038/26620

10.1128/JB.180.12.3205-3208.1998

10.1073/pnas.091110398

10.1046/j.1365-2958.1999.01414.x

10.1093/pcp/pcd031

10.1093/emboj/21.4.572

10.1016/0014-5793(86)81172-3

10.1016/S0014-5793(01)02931-3

10.1006/jmbi.1996.0449

10.1111/j.1432-1033.1996.0081r.x

Thông tin
Thông tin xuất bản

Comparative and Functional Genomics

Tập 4 Số 1

31-36

Thông tin tác giả