Cellular and Molecular Life Sciences

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Cellular and Molecular Life Sciences - Tập 40 - Trang 230-230 - 1984
G. Bynke, R. Håkanson, J. Hörig
Disaccharidase rhythm in rat small intestine; no relationship with mitosis rhythm
Cellular and Molecular Life Sciences - Tập 34 - Trang 700-701 - 1978
Masayuki Saito, Masami Suda
Same circadian difference in the specific activities of sucrase and maltase was observed in the purified brush border fraction as in the crude homogenate of the mucosa of rat small intestine, suggesting that the disaccharidase rhythm is not due to the mitosis rhythm of epithelial cells.
Agonist-induced internalization and desensitization of the human nociceptin receptor expressed in CHO cells
Cellular and Molecular Life Sciences - - 2002
Santi Spampinato, Rosanna Di Toro, Marco Alessandri, G Murari
Avian influenza viruses infecting humans
Cellular and Molecular Life Sciences - Tập 57 Số 12 - Trang 1770-1784 - 2000
Kanta Subbarao, Jacqueline M. Katz
Ctenidins: antimicrobial glycine-rich peptides from the hemocytes of the spider Cupiennius salei
Cellular and Molecular Life Sciences - Tập 67 - Trang 2787-2798 - 2010
Tommy Baumann, Urs Kämpfer, Stefan Schürch, Johann Schaller, Carlo Largiadèr, Wolfgang Nentwig, Lucia Kuhn-Nentwig
Three novel glycine-rich peptides, named ctenidin 1–3, with activity against the Gram-negative bacterium E. coli, were isolated and characterized from hemocytes of the spider Cupiennius salei. Ctenidins have a high glycine content (>70%), similarly to other glycine-rich peptides, the acanthoscurrins, from another spider, Acanthoscurria gomesiana. A combination of mass spectrometry, Edman degradati...... hiện toàn bộ
Vector-based RNA interference of cathepsin B1 in Schistosoma mansoni
Cellular and Molecular Life Sciences - Tập 67 - Trang 3739-3748 - 2010
Elissaveta B. Tchoubrieva, Poh C. Ong, Robert N. Pike, Paul J. Brindley, Bernd H. Kalinna
In helminth parasites, proteolytic enzymes have been implicated in facilitating host invasion, moulting, feeding, and evasion of the host immune response. These key functions render them potential targets for anti-parasite chemotherapy and immunotherapy. Schistosomes feed on host blood and the digested haemoglobin is their major source of amino acids. Haemoglobin digestion is essential for parasit...... hiện toàn bộ
Intracellular protein degradation in mammalian cells: recent developments
Cellular and Molecular Life Sciences - Tập 66 - Trang 2427-2443 - 2009
Erwin Knecht, Carmen Aguado, Jaime Cárcel, Inmaculada Esteban, Juan Miguel Esteve, Ghita Ghislat, José Félix Moruno, José Manuel Vidal, Rosana Sáez
In higher organisms, dietary proteins are broken down into amino acids within the digestive tract but outside the cells, which incorporate the resulting amino acids into their metabolism. However, under certain conditions, an organism loses more nitrogen than is assimilated in the diet. This additional loss was found in the past century to come from intracellular proteins and started an intensive ...... hiện toàn bộ
Plant ribosome-inactivating proteins type II induce the unfolded protein response in human cancer cells
Cellular and Molecular Life Sciences - Tập 68 - Trang 1269-1281 - 2010
C. Horrix, Z. Raviv, E. Flescher, C. Voss, M. R. Berger
Cytotoxic ribosome-inactivating proteins (RIPs) of type II such as ricin were investigated as anti-cancer agents, but also pose a threat as biological weapons. The molecular mechanism leading to their toxic effects is, however, not yet clear. The current paradigm, which states that the irreversible depurination of 28S rRNA results in a general translational arrest eventually leading to cell death,...... hiện toàn bộ
Erratum to: Molecular mechanisms in therapy of acid-related diseases
Cellular and Molecular Life Sciences - Tập 68 - Trang 921-921 - 2011
J. M. Shin, O. Vagin, K. Munson, M. Kidd, I. M. Modlin, G. Sachs
CMLS forum reviews: mitochondrial damage control
Cellular and Molecular Life Sciences - Tập 78 - Trang 3763-3765 - 2021
Anne Hamacher-Brady
Mitochondria supply cellular energy through oxidative phosphorylation and fulfill numerous additional functions that are fundamental to cellular homeostasis and stress responses. Mitochondrial malfunction, arising from inherent defects of the organelle itself, aging, or acute or chronic stress, can cause substantial damage to organismal health. For instance, mitochondrial malfunction contributes t...... hiện toàn bộ
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