THE EFFECT OF CYTOCHALASIN J ON KINETOCHORE STRUCTURE IN PTK1CELLS IS MITOTIC CYCLE DEPENDENTCell Biology International - Tập 25 - Trang 815-820 - 2001
Gregory A. Wrench, Judith A. Snyder
Mitotic PtK1cells were arrested in mitosis with nocodazole to determine the effect of cytochalasin J (CJ) on kinetochore structure in arrested and nocodazole‐released cells. In previous studies it was shown that CJ had a more pronounced effect on alteration of kinetochore structure and spindle microtubule (MT) architecture when applied during prophase or prometaphase. ...... hiện toàn bộ
Changes in signaling pathways of cell proliferation and apoptosis during NK/Ly lymphoma agingCell Biology International - Tập 32 - Trang 1057-1063 - 2008
R.R. Panchuk, N.M. Boiko, M.D. Lootsik, R.S. Stoika
AbstractExpression of specific proteins involved in regulation of cell proliferation and apoptosis was studied at the initial (7–8 days after tumor inoculation), median (13–14 days), and terminal (20–21 days) stages of murine NK/Ly lymphoma development. Western‐blot analysis using antibodies to MEK—ERK signaling pathway, E2F‐1/2 and c‐Myc, pSTAT1, pSTAT3, pSTAT5, a...... hiện toàn bộ
Comparison between osteoblasts derived from human dental pulp stem cells and osteosarcoma cell linesCell Biology International - Tập 32 - Trang 733-738 - 2008
Annalisa Palmieri, Furio Pezzetti, Antonio Graziano, D'Aquino Riccardo, Ilaria Zollino, Giorgio Brunelli, Marcella Martinelli, Marzia Arlotti, Francesco Carinci
AbstractStem cells derived from human dental pulp are able to differentiate into osteoblasts and are a potential source of autologous bone. The aim of this study was to compare genes differentially expressed in osteoblastoids from human dental pulp (OHDP) to osteosarcoma cells (OCs).Human dental pulp was extracted and immersed in a digestive soluti...... hiện toàn bộ
Induction of apoptosis by Hax‐1 siRNA in melanoma cellsCell Biology International - Tập 33 - Trang 548-554 - 2009
Wen-Bin Li, Jie Feng, Song-Mei Geng, Peng-Yu Zhang, Xiao-Ning Yan, Gang Hu, Cai-Qing Zhang, Bing-Jun Shi
AbstractHS1‐associated protein X‐1 (Hax‐1) is a novel intracellular protein and recent studies suggested that it is an anti‐apoptotic factor in different tumors. Hax‐1 expression was upregulated in various metastatic tumors and cancer cell lines, including melanoma. To understand the role of Hax‐1 in melanoma development and progression, we constructed Hax‐1 short ...... hiện toàn bộ
MOSQUITO LARVAE PROTEINS MODULATE LUTEINIZING HORMONE AND PROLACTIN RELEASE IN PITUITARY CELLS OF NORMAL AND ESTROGENIZED RATSCell Biology International - Tập 25 - Trang 139-146 - 2001
Federico Bolognani, Rodolfo Gustavo Goya, Jorge Rafael Ronderos
Whilst looking for vertebrate growth factor homologues in insects, we found that a soluble fraction of a 12–80kDa molecular weight band peaking at 25kDa, isolated from mosquito larvae extracts by gel permeation chromatography, had a modulatory effect on mouse hepatocytes and adult human mononuclear cell proliferation. The effect disappeared after heating the extract at 90°C for 30min, sugg...... hiện toàn bộ
RBP‐Jκ binds to and represses transcription of the p53 tumor suppressor geneCell Biology International - Tập 33 - Trang 318-324 - 2009
Kristy Boggs, Brystol Henderson, David Reisman
AbstractThe tightly regulated expression of p53 contributes to genomic stability and transcription of the p53 gene is induced prior to cells entering S‐phase, possibly as a mechanism to insure a rapid p53 response in the event of DNA damage. We have previously described the cloning of an additional 1000 bp of upstream p53 sequences that p...... hiện toàn bộ