Cell Biology International
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ESTROGEN DOWNREGULATES THE NUMBER OF CAVEOLAE AND THE LEVEL OF CAVEOLIN IN UTERINE SMOOTH MUSCLEEstrogen and progesterone, while regulating uterine functions, also regulate the number of caveolae and the level of caveolin. Large numbers of caveolae, as well as elevated expression of caveolin‐1 and caveolin‐2 isoforms in the myometrium of ovariectomised (OVX) rats were detected. 17β‐estradiol (E2) has a downregulating effect: the treatment of OVX rats with E2 (5μg/animal) reduced the ... ... hiện toàn bộ
Cell Biology International - Tập 25 - Trang 785-794 - 2001
Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cellsAbstract This study demonstrates cytotoxic and genotoxic potential of juglone, a chief constituent of walnut, and its underlying mechanisms against melanoma cells. MTT assay and clonogenic assay were used to study cytotoxicity, micronucleus assay to assess genotoxicity, glutathione (GSH) assay and 2′,7′‐dicholorofluorescein diacetate (DCFH‐DA) assay to evaluate the ... ... hiện toàn bộ
Cell Biology International - Tập 33 - Trang 1039-1049 - 2009
Rho activation is required for transforming growth factor‐β‐induced epithelial‐mesenchymal transition in lens epithelial cellsAbstract Lens epithelial cells undergo epithelial‐mesenchymal transition (EMT) after injury as in cataract extraction, leading to fibrosis of the lens capsule. We have recently shown that TGF‐β‐induced EMT in lens epithelial cells depends on PI3 kinase/Akt signal pathway. In this report, we suggest Smad3 is necessary for TGF‐β‐induced EMT by showing that the express... ... hiện toàn bộ
Cell Biology International - Tập 31 - Trang 1225-1230 - 2007
HYDROGEN PEROXIDE INDUCES APOPTOSIS IN HUMAN HEPATOMA CELLS AND ALTERS CELL REDOX STATUS
Cell Biology International - Tập 24 - Trang 9-23 - 2000
Metal‐binding proteins in eggs of various sea urchin species.Abstract Metallothionein presence and amount were determined in the unfertilized eggs of six sea urchin species by silver saturation assay and gel‐chromatography of cell extracts. The results showed high levels of metallothionein in the egg cytoplasm of the two Mediterranean species Paracentrotus lividus and Sphaerechinus granularis. No metallothionein was found eit... ... hiện toàn bộ
Cell Biology International - Tập 18 - Trang 47-54 - 1994
EFFECTS OF DIPEPTIDES CONTAINING THE AMINO ACID, PROLINE ON THE CHEMOTAXIS OF TETRAHYMENA PYRIFORMIS. EVOLUTIONARY CONCLUSIONS ON THE FORMATION OF HORMONE RECEPTORS AND HORMONESOur investigations demonstrate that proline‐containing dipeptides can provoke a chemosensory response from the unicellular Tetrahymena pyriformis The chemotactic effects of the dipeptides have a close relationship with the side chain and the lipophilicity of the amino‐terminal amino acid. Comparison of ‘mirror’ variants of proline‐containing dipeptides points to ... ... hiện toàn bộ
Cell Biology International - Tập 21 - Trang 341-345 - 1997
Regulation of paracellular Na+ and Cl− conductances by hydrostatic pressureAbstract The effect of hydrostatic pressure on the paracellular ion conductance (Gp) composed of the Na+ conductance (GNa ) and the Cl− conductance (GCl ) has been Investigated. Gp, GNa and GCl were time‐dependently increased after applying an ... ... hiện toàn bộ
Cell Biology International - Tập 33 - Trang 949-956 - 2009
YẾU TỐ TĂNG TRƯỞNG HEPATOCYTE HỖ TRỢ SỰ KÍCH THÍCH CỦA ANDROGEN TRONG SỰ TĂNG TRƯỞNG CỦA CÁC TẾ BÀO BIỂU MÔ TUYẾN TIỀN LIỆT VENTRAL CỦA MOUSE TRONG NUÔI CẤY MÁTRI COLLAGEN GEL Dịch bởi AI Để đánh giá vai trò của yếu tố tăng trưởng tế bào gan (HGF) và androgen trong sự phát triển của các tế bào biểu mô tuyến tiền liệt, chúng tôi đã tách biệt các tế bào biểu mô tuyến tiền liệt ventral của chuột và nuôi cấy chúng trong ma trận gel collagen loại I ba chiều dưới điều kiện không có huyết thanh. Mặc dù các tế bào biểu mô tuyến tiền liệt có xu hướng chết trong môi trường cơ sở có b... ... hiện toàn bộ
Cell Biology International - Tập 23 - Trang 373-377 - 1999
DEVELOPMENTAL REGULATION OF GRANULE SIZE AND NUMBERS IN LARVAL SALIVARY GLANDS OF DROSOPHILA BY STEROID HORMONE ECDYSONEAbstract The size and number of secretory granules in late larval salivary glands of Drosophila melanogaster have been related to interecdysial and early metamorphic development represented by well‐known puffs in polytene chromosomes. Interecdysial period (puff stage 1 (PS1)) is characterized by presence of numerous small granules (11,000 ... ... hiện toàn bộ
Cell Biology International - Tập 23 - Trang 671-676 - 1999
SPATIAL DISTRIBUTION OF mDLG6 mRNA IN EMBRYONIC AND ADULT MOUSE BRAINAbstract We have isolated mouse DLG6 (mDLG6) cDNA clones by RT‐PCR and then by using the RT‐PCR products to screen a mouse brain cDNA library. The deduced amino acid sequence of mDLG6 shows 79.2% and 82.7% overall identity to human (hDLG6) and rat DLG6 (rDLG6), respectively. In situ hybridization revealed that mDLG6 mRNA is predominantly e...
Cell Biology International - Tập 26 - Trang 635-640 - 2002
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