Cardiovascular Engineering: An International Journal
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A Right Ventricular Pressure Waveform Based Pulse Contour Cardiac Output Algorithm in Canines
Cardiovascular Engineering: An International Journal - Tập 6 - Trang 83-92 - 2006
Tracking changes in stroke volume or cardiac output (CO) can be useful in the
diagnosis and treatment of various cardiac illnesses. Existing arterial pressure
waveform based pulse contour CO algorithms perform poorly during altered
systemic hemodynamics. In this study, a right ventricular pressure waveform
based pulse contour CO algorithm was developed to estimate the amplitude and
duration of a h...
Estimation of Nonlinear Mechanical Properties of Vascular Tissues via Elastography
Cardiovascular Engineering: An International Journal - Tập 8 Số 4 - Trang 191-202 - 2008
A new method is proposed for estimation of nonlinear elastic properties of soft
tissues. The proposed approach involves a combination of nonlinear finite
element methods with a genetic algorithm for estimating tissue stiffness
profile. A multipoint scheme is introduced that satisfies the uniqueness
condition, improves the estimation performance, and reduces the sensitivity to
image noise. The util...
A Computational Approach to Predict Pulse Transit Time Variations During Postural Change
Cardiovascular Engineering: An International Journal - Tập 7 - Trang 121-126 - 2007
The human autonomic nervous system modulates blood pressure (BP) and heart rate
in order to maintain homeostasis. Present techniques that monitor BP may cause
discomforts to children. Pulse transit time change (ΔPTT) is known to be
inversely correlated to BP change. In this study, a mathematical model using
only a few empirical parameters and the measured lower limb vascular path length
is introdu...
Modelling of the Blood Flow Circulation in the Human Foetus by the End of the Third Week of Gestation
Cardiovascular Engineering: An International Journal - Tập 5 - Trang 29-35 - 2005
Pumping blood in one direction is the main function of the heart, which is
equipped with valves that ensure unidirectional flow. During early embryonic
life, blood circulates in one direction through the primitive circulatory
system, in spite of the complete lack of valves. A mathematical model has been
developed in order to describe the coordinated fashion of the blood circulation
in the circulat...
Biological Asymmetry and Cardiovascular Blood Transport
Cardiovascular Engineering: An International Journal - Tập 4 - Trang 209-218 - 2004
Asymmetry is a very remarkable property of biological structures and functions.
Most publications concerning asymmetry are related to brain function. However,
as will be shown in this study, the asymmetry in the cardiovascular system plays
an important role with respect to optimization of functions. Weibel (Cambridge,
MA, 2000) has used the name “symmorphosis” to describe the ideal interrelation
b...
A Mathematical Model of Mean Airway Pressure Based Upon Positive End-Expiratory Pressure, I:E Ratio, and Plateau Pressure
Cardiovascular Engineering: An International Journal - Tập 3 - Trang 131-139 - 2003
A mathematical model of mean airway pressure (P mean) has been derived which is
based upon positive end-expiratory pressure (P peep) and I:E ratio (I:E).
Plateau pressure (P PL) is also utilized: $$ P_{\rm mean}/P_{\rm PL} = [(I{:}E)
+ {\bf R}]/[(I{:}E) + 1] $$ where R is defined as: R = P peep/P PL. Based upon
this model, it can be shown that (1) increasing I:E ratio will increase P mean/P
PL in ...
Numerical Simulation of Hemodynamic and Physiological Responses of Human Cardiovascular and Respiratory System under Drugs Administration
Cardiovascular Engineering: An International Journal - Tập 4 - Trang 295-304 - 2004
The uptake of the drugs by human organisms has long been one of the primary
concerns of pharmacological research. The numerical model of the human
cardiovascular and respiratory system with the baroreflex and chemoreflex
regulation including the physiologically-based pharmacokinetic model and also
the model of the drug-cardiac cell channels interaction is developed at the IT
CAS. The 24th segments...
A Servo-controlled Canine Model of Stable Severe Ischemic Left Ventricular Failure
Cardiovascular Engineering: An International Journal - Tập 9 - Trang 144-152 - 2009
Reversible left ventricular failure was produced in conscious dogs by compromise
of the coronary circulation. In animals with prior left anterior descending
coronary artery occlusion, mean left atrial pressure (LAP) was incorporated into
an automatic feedback control system used to inflate a balloon cuff on the
circumflex (Cfx) coronary artery. The system could produce stable increases in
LAP to 1...
Green Fluorescent Protein-Transgenic Rat as a Tool for Study of Transplantation and Regeneration in Myocardium
Cardiovascular Engineering: An International Journal - Tập 3 - Trang 63-69 - 2003
Cell transplantation and regeneration therapy are potentially new therapeutic
approaches for cardiovascular disease. Transgenic (tg) animals for reporter
genes would be useful to follow the cell lineage and differentiation during
development and regeneration processes. In the present study, we developed green
fluorescent protein (GFP)-tg rats and evaluated them as a tool for the study of
cardiomyo...
Patterns of Cardiovascular Control During Repeated Tests of Orthostatic Loading
Cardiovascular Engineering: An International Journal - Tập 9 - Trang 134-143 - 2009
To investigate patterns of cardiovascular control, a protocol of head up tilt
(HUT) followed by lower body negative pressure (LBNP), which represents a
significant cardiovascular control challenge, was employed. Linear regression of
beat-to-beat heart rate (HR) and mean blood pressure (MBP) data collected over
repeated tests was used to analyze control response during the LBNP phase of the
combine...
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