Evaluation of a 2D Model of the Left Side of the Human Heart Against Magnetic Resonance Velocity Mapping
Tóm tắt
The purpose of this study is to determine whether an existing 2D mathematical model of the heart developed by Peskin and Mcqueen can be modified, so it can simulate blood flow patterns in the left ventricle as measured by magnetic resonance (MR) phase contrast velocity mapping. The modifications comprise changing the geometry of the heart model of the plane section together with the tuning of parameters describing the myocardium and the activation timing of the myocardium. The results include detailed velocity maps during a heart cycle, from which are extracted the time course of velocities of the flow through the mitral valve and the aortic outflow tract, and the size and angular speed of a vortex in the left ventricle. Despite the inherent deficiency of a 2D modeling of a 3D phenomenon, fair agreement is obtained between simulated results and measurements.
Tài liệu tham khảo
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