Recommendations for the registration of new chemical entities used in the prevention and treatment of osteoporosisCalcified Tissue International - Tập 57 - Trang 247-250 - 1995
J. Y. Reginster, J. E. Compston, E. A. Jones, J. M. Kaufman, M. Audran, G. Bouvenot, L. Frati, G. Mazzuoli, C. Gennari, E. -M. Lemmel, J. D. Ringe, J. -L. Sebert, L. Vanhaelst, B. Avouac
Serum bone GLA-protein is not a sensitive marker of bone turnover in Paget's disease of boneCalcified Tissue International - Tập 38 - Trang 60-61 - 1986
P. D. Delmas, B. Demiaux, L. Malaval, M. C. Chapuy, P. J. Meunier
Serum bone Gla-protein (sBGP) was measured in 32 patients with untreated Paget's
disease of bone. Despite clinical and biological symptoms of active disease in
all patients, sBGP was normal in 13/32 patients (41%). There was a striking
discrepancy between the moderate increase of sBGP above normal values (11.4±4.5
vs 6.0±2.1 ng/ml) and the marked increase of both serum alkaline phosphatase
(sAP) a... hiện toàn bộ
Bone Marrow Microenvironment as a Regulator and Therapeutic Target for Prostate Cancer Bone MetastasisCalcified Tissue International - Tập 102 - Trang 152-162 - 2017
Sun H. Park, Evan T. Keller, Yusuke Shiozawa
Bone is the most common site of prostate cancer metastasis. Once prostate cancer
cells metastasize to bone, the mortality rate of prostate cancer patients
increases significantly. Furthermore, bone metastases produce multiple skeletal
complications, including bone pain that impairs the patients’ quality of life.
Effective therapies for bone metastatic disease are underdeveloped with most
current t... hiện toàn bộ
EditorialCalcified Tissue International - Tập 39 - Trang 1-1 - 1986
Louis V. Avioli
Association Analysis of Bone Mineral Density and Single Nucleotide Polymorphisms in Two Candidate Genes on Chromosome 1p36Calcified Tissue International - Tập 73 - Trang 140-146 - 2003
L. D. Spotila, H. Rodriguez, M. Koch, H. S. Tenenhouse, A. Tenenhouse, H. Li, M. Devoto
Two candidate genes for bone mineral density (BMD), tumor necrosis factor alpha
receptor 2 (TNFRSF1B) and lysyl hydroxylase (PLOD1), have been scanned for
single nucleotide polymorphisms (SNPs) within their coding and promoter regions.
These two genes, separated by about 200 kb, are located within the chromosomal
interval 1p36.2–1p36.3 that has been linked to femoral neck BMD. In a patient
populat... hiện toàn bộ