AbstractTriple-negative breast cancer (TNBC), a specific subtype of breast
cancer that does not express estrogen receptor (ER), progesterone receptor (PR),
or human epidermal growth factor receptor 2 (HER-2), has clinical features that
include high invasiveness, high metastatic potential, proneness to relapse, and
poor prognosis. Because TNBC tumors lack ER, PR, and HER2 expression, they are
not s... hiện toàn bộ
Carol Sheridan, Hiroyuki Kishimoto, Robyn K. Fuchs, Sanjana Mehrotra, Poornima Bhat‐Nakshatri, Charles H. Turner, Robert J. Goulet, Sunil Badve, Harikrishna Nakshatri
Elgene Lim, Di Wu, Bhupinder Pal, Toula Bouras, Marie Liesse Asselin-Labat, François Vaillant, Hideo Yagita, Geoffrey J. Lindeman, Gordon K. Smyth, Jane E. Visvader
Torsten Stein, Joanna S. Morris, Claire Davies, Stephen J. Weber-Hall, Marie Anne Pringle, Victoria J. Heath, Alison M. Bell, Roderick K. Ferrier, G. P. Sandilands, Barry A. Gusterson
Eleni van Schooneveld, Hans Wildiers, Ignace Vergote, Peter B Vermeulen, Luc Y Dirix, Steven J Van Laere
MicroRNAs (miRNAs) are an emerging class of gene expression modulators with
relevant roles in several biological processes, including cell differentiation,
development, apoptosis, and regulation of the cell cycle. Deregulation of those
tiny RNA molecules has been described frequently as a major determinant for the
initiation and progression of diseases, including cancer. Not only miRNAs but
also t... hiện toàn bộ