Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3
Tóm tắt
Từ khóa
Tài liệu tham khảo
Richert MM, Schwertfeger KL, Ryder JW, Anderson SM: An atlas of mouse mammary gland development. J Mammary Gland Biol Neoplasia. 2000, 5: 227-241. 10.1023/A:1026499523505.
Masso-Welch PA, Darcy KM, Stangle-Castor NC, Ip MM: A developmental atlas of rat mammary gland histology. J Mammary Gland Biol Neoplasia. 2000, 5: 165-185. 10.1023/A:1026491221687.
Lund LR, Romer J, Thomasset N, Solberg H, Pyke C, Bissell MJ, Dano K, Werb Z: Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways. Development. 1996, 122: 181-193.
Li M, Liu X, Robinson G, Bar-Paled U, Wagner K-U, Young WS, Hennighausen L, Furth PA: Mammary derived signals activate programmed cell during the involuting mammary gland. Proc Natl Acad Sci USA. 1997, 94: 3425-3430. 10.1073/pnas.94.7.3425.
Marti A, Lazar H, Ritter P, Jaggi R: Transcription factor activities and gene expression during mouse mammary gland involution. J Mammary Gland Biol Neoplasia. 1999, 4: 145-152. 10.1023/A:1018721107061.
Master SR, Hartman JL, D'Cruz CM, Moody SE, Keiper EA, Ha SI, Cox JD, Belka GK, Chodosh LA: Functional microarray analysis of mammary organogenesis reveals a developmental role in adaptive thermogenesis. Mol Endocrinol. 2000, 16: 1185-1203. 10.1210/me.16.6.1185.
Clarkson RWE, Wayland MT, Lee J, Freeman T, Watson CJ: Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression. Breast Cancer Res. 2004, 6: R92-R109. 10.1186/bcr754.
Eckersall PD: Recent advances and future prospects for the use of acute phase proteins as markers of disease in animals. Revue Méd Vét. 2000, 151: 577-584.
Dinarello CA: Interleukin-1 and the pathogenesis of the acute phase response. New Engl J Med. 1984, 311: 1413-1418.
Heinrich PC, Castell JC, Andus T: Interleukin-6 and the acute phase response. Biochem J. 1990, 265: 621-636.
Beutler B, Cerami A: Cachectin/tumor necrosis factor: an endogenous mediator of shock and inflammation. Immunol Res. 1986, 5: 281-293.
Anderson JC: The increased resistance of mice to experimental staphylococcal mastitis following inoculation of endotoxin. Res Vet Sci. 1976, 21: 64-68.
Chapman RS, Lourenco PC, Tonner E, Flint DJ, Selbert S, Takeda K, Akira S, Clarke AR, Watson CJ: Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3. Genes Dev. 1999, 13: 2604-2616. 10.1101/gad.13.19.2604.
Humphreys RC, Bierie B, Zhao L, Raz R, Levy D, Hennighausen L: Deletion of Stat3 blocks mammary gland involution and extends functional competence of the secretory epithelium in the absence of lactogenic stimuli. Endocrinology. 2002, 143: 3641-3650. 10.1210/en.2002-220224.
Akira S, Nishio Y, Inoue M, Wang XJ, Wei S, Matsusaka T, Yoshida K, Sudo T, Naruta M, Kishimoto T: Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell. 1994, 77: 63-71.
Zhong Z, Wen Z, Darnell JE: Stat3: a new family member that is activated through tyrosine phosphorylation in response to EGF and IL-6. Science. 1994, 264: 95-98.
Trautwein C, Rakemann T, Niehof M, Rose-John S, Manns MP: Acute-phase response factor, increased binding, and target gene transcription during liver regeneration. Gastroenterology. 1996, 110: 1854-1862.
Schumann RR, Kirschning CJ, Unbehaun A, Aberle HP, Knope HP, Lamping N, Ulevitch RJ, Herrmann F: The lipopolysaccharide-binding protein is a secretory class 1 acute-phase protein whose gene is transcriptionally activated by APRF/STAT-3 and other cytokine-inducible nuclear proteins. Mol Cell Biol. 1996, 16: 3490-3503.
Cantwell CA, Sterneck E, Johnson PF: Interleukin-6-specific activation of the C/EBPdelta gene in hepatocytes is mediated by Stat3 and Sp1. Mol Cell Biol. 1998, 18: 2108-2117.
Boudreau F, Yu SJ, Asselin C: CCAAT/enhancer binding proteins beta and delta regulate alpha1-acid glycoprotein gene expression in rat intestinal epithelial cells. DNA Cell Biol. 1998, 17: 669-677.
Alam T, An MR, Papaconstantinou J: Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response. J Biol Chem. 1992, 267: 5021-5024.
Pan Z, Hetherington CJ, Zhang DE: CCAAT/enhancer-binding protein activates the CD14 promoter and mediates transforming growth factor beta signaling in monocyte development. J Biol Chem. 1999, 274: 23242-23248. 10.1074/jbc.274.33.23242.
Devitt A, Moffa OD, Raykundalia C, Capra JD, Simmons DL, Gregory CD: Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature. 1998, 392: 505-509. 10.1038/33169.
Wright SD: CD14: a leukocyte membrane protein that functions in the response to endotoxin [abstract]. FASEB J. 1990, 4: A1848-
Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC: CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science. 1990, 249: 1431-1433.
Paape MJ, Lillius EM, Wiitanen PA, Kontio MP: Intramammary defense against infections induced by Escherichia coli in cows. Am J Vet Res. 1996, 57: 477-482.
Labeta MO, Vidal K, Nores JE, Arias M, Vita N, Morgan BP, Guillemot JC, Loyaux D, Ferrara P, Schmid D, Affolter M, Borysiewicz LK, Donnet-Hughes A, Schiffrin EJ: Innate recognition of bacteria in human milk is mediated by a milk-derived highly expressed pattern recognition receptor, soluble CD14. J Exp Med. 2000, 191: 1807-1812. 10.1084/jem.191.10.1807.
Walker NI, Bennett RE, Kerr JFR: Cell death by apoptosis during involution of the lactating breast in mice and rats. Am J Anat. 1989, 185: 19-32.
Fadok VA: Clearance: the last and often forgotten stage of apoptosis. J Mammary Gland Biol Neoplasia. 1999, 4: 203-211. 10.1023/A:1011384009787.
Monks J, Geske FJ, Lehman L, Fadok VA: Do inflammatory cells participate in mammary gland involution?. J Mammary Gland Biol Neoplasia. 2002, 7: 163-176. 10.1023/A:1020351919634.
Gregory CD: CD14-dependent clearance of apoptotic cells: relevance to the immune system. Curr Opin Immunol. 2000, 12: 27-34. 10.1016/S0952-7915(99)00047-3.
Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM: Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrinemechanisms involving TGF β, PGE2, and PAF. J Clin Invest. 1998, 1001: 890-898.
Laurent PE: Clinical measurement of acute phase proteins to detect and monitor infectious disease. In Acute Phase Proteins in the Acute Phase Response. Edited by: Pepys MB. 1989, New York: Springer-Verlag, 151-159.
Jin FY, Nathan C, Radzioch D, Ding A: Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide. Cell. 1997, 88: 417-426.
Zhu J, Nathan C, Jin W, Sim D, Ashcroft GS, Wahl SM, Lacomis L, Erdjument-Bromage H, Tempst P, Wright CD, Ding A: Conversion of proepithelin to epithelins. Roles of SLPI and elastase in host defense and wound repair. Cell. 2002, 111: 867-878.
Lutticken C, Wegenka UM, Yuan J, Buschmann J, Schindler C, Ziemiecki A, Harpur AG, Wilks AF, Yasukawa K, Taga T: Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130. Science. 1994, 263: 89-92.
Hutt JA, DeWille JW: Oncostatin M induces growth arrest of mammary epithelium via a CCAAT/enhancer-binding protein delta-dependent pathway. Mol Cancer Ther. 2002, 1: 601-610.
Grant SL, Douglas AM, Goss GA, Begley CG: Oncostatin M and leukemia inhibitory factor regulate the growth of normal human breast epithelial cells. Growth Factors. 2001, 19: 153-162.
Schere-Levy C, Buggiano V, Quaglino A, Gattelli A, Cirio MC, Piazzon I, Vanzulli S, Kordon EC: Leukemia inhibitory factor induces apoptosis of the mammary epithelial cells and participates in mouse mammary gland involution. Exp Cell Res. 2003, 282: 35-47. 10.1006/excr.2002.5666.
Kritikou EA, Sharkey A, Abell K, Came PJ, Anderson E, Clarkson RWE, Watson CJ: A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland. Development. 2003, 130: 3459-3468. 10.1242/dev.00578.
Lee CS, McDowell GH, Lascelles AK: The importance of macrophages in the removal of fat from the involuting mammary gland. Res Vet Sci. 1969, 10: 34-38.
Lee CS, McCauley I, Hartmann PE: Light and electron microscopy of cells in pig colostrum, milk and involution secretion. Acta Anat. 1983, 116: 126-135.
Colditz IG: Studies on the inflammatory response during involution of the ovine mammary gland. Q J Exp Physiol. 1988, 73: 363-368.
O'Donnell LC, Druhan LJ, Avalos BR: Molecular characterization and expression analysis of leucine-rich alpha2-glycoprotein, a novel marker of granulocytic differentiation. J Leukoc Biol. 2002, 72: 478-485.
Engelhardt E, Toksoy A, Goebeler M, Debus S, Brocker EB, Gillitzer R: Chemokines IL-8, GROalpha, MCP-1, IP-10, and Mig are sequentially and differentially expressed during phase-specific infiltration of leukocyte subsets in human wound healing. Am J Pathol. 1998, 153: 1849-1860.
Wiekowski MT, Chen SC, Zalamea P, Wilburn BP, Kinsley DJ, Sharif WW, Jensen KK, Hedrick JA, Manfra D, Lira SA: Disruption of neutrophil migration in a conditional transgenic model: evidence for CXCR2 desensitization in vivo. J Immunol. 2001, 167: 7102-7110.
Aubry F, Habasque C, Satie AP, Jegou B, Samson M: Expression and regulation of the CXC-chemokines, GRO/KC and IP-10/ mob-1 in rat seminiferous tubules. Eur Cytokine Netw. 2000, 11: 690-698.
Heeckeren A, Walenga R, Konstan MW, Bonfield T, Davis PB, Ferkol T: Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa. J Clin Invest. 1997, 100: 2810-2815.
Jones CE, Chan K: Interleukin-17 stimulates the expression of interleukin-8, growth-related oncogene-alpha, and granulocyte-colony-stimulating factor by human airway epithelial cells. Am J Respir Cell Mol Biol. 2002, 26: 748-753.
Mehrad B, Strieter RM, Moore TA, Tsai WC, Lira SA, Standiford TJ: CXC chemokine receptor-2 ligands are necessary components of neutrophil-mediated host defense in invasive pulmonary aspergillosis. J Immunol. 1999, 163: 6086-6094.
Endlich B, Armstrong D, Brodsky J, Novotny M, Hamilton TA: Distinct temporal patterns of macrophage-inflammatory protein-2 and KC chemokine gene expression in surgical injury. J Immunol. 2002, 168: 3586-3594.
Rovai LE, Herschman HR, Smith JB: The murine neutrophil-chemoattractant chemokines LIX, KC, and MIP-2 have distinct induction kinetics, tissue distributions, and tissue-specific sensitivities to glucocorticoid regulation in endotoxemia. J Leukoc Biol. 1998, 64: 494-502.
Anisowicz A, Zajchowski D, Stenman G, Sager R: Functional diversity of GRO gene expression in human fibroblasts and mammary epithelial cells. Proc Nat Acad Sci USA. 1988, 85: 9645-9649.
Paape M, Mehrzad J, Zhao J, Detilleux J, Burvenich C: Defense of the bovine mammary gland by polymorphonuclear neutrophil leukocytes. J Mammary Gland Biol Neoplasia. 2002, 7: 109-121. 10.1023/A:1020343717817.
Gouon-Evans V, Rothenberg ME, Pollard JW: Postnatal mammary gland development requires macrophages and eosinophils. Development. 2000, 127: 2269-2282.
Sleeman MA, Fraser JK, Murison JG, Kelly SL, Prestidge RL, Palmer DJ, Watson JD, Kumble KD: B cell- and monocyte-activating chemokine (BMAC), a novel non-ELR alpha-chemokine. Int Immunol. 2000, 12: 677-689. 10.1093/intimm/12.5.677.
Kurth I, Willimann K, Schaerli P, Hunziker T, Clark-Lewis I, Moser B: Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development. J Exp Med. 2001, 194: 855-861. 10.1084/jem.194.6.855.
Myokai F, Takashiba S, Lebo R, Amar S: A novel lipopolysaccharide-induced transcription factor regulating tumor necrosis factor α gene expression: molecular cloning, sequencing, characterization, and chromosomal assignment. Proc Natl Acad Sci USA. 1999, 96: 4518-4523. 10.1073/pnas.96.8.4518.
Kushner I, Mackiewicz A: Acute phase proteins as disease markers. Dis Markers. 1987, 5: 1-11.
Hochepied T, Berger FG, Baumann H, Libert C: α1-acid glycoprotein: and acute phase protein with inflammatory and immunomodulating properties. Cyt Growth Factor Rev. 2003, 14: 25-34. 10.1016/S1359-6101(02)00054-0.
Gitlin JD: Transcriptional regulation of ceruloplasmin gene expression during inflammation. J Biol Chem. 1988, 263: 6281-6287.