The influence of mammogram acquisition on the mammographic density and breast cancer association in the mayo mammography health study cohortBreast Cancer Research - Tập 14 - Trang 1-12 - 2012
Janet E Olson, Thomas A Sellers, Christopher G Scott, Beth A Schueler, Kathleen R Brandt, Daniel J Serie, Matthew R Jensen, Fang-Fang Wu, Marilyn J Morton, John J Heine, Fergus J Couch, V Shane Pankratz, Celine M Vachon
Mammographic density is a strong risk factor for breast cancer. Image acquisition technique varies across mammograms to limit radiation and produce a clinically useful image. We examined whether acquisition technique parameters at the time of mammography were associated with mammographic density and whether the acquisition parameters confounded the density and breast cancer association. We examine...... hiện toàn bộ
Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosisBreast Cancer Research - Tập 20 - Trang 1-16 - 2018
Arantzazu Zubeldia-Plazaola, Leire Recalde-Percaz, Núria Moragas, Mireia Alcaraz, Xieng Chen, Mario Mancino, Patricia Fernández-Nogueira, Miquel Prats de Puig, Flavia Guzman, Aleix Noguera-Castells, Anna López-Plana, Estel Enreig, Neus Carbó, Vanessa Almendro, Pedro Gascón, Paloma Bragado, Gemma Fuster
The microenvironment and stress factors like glucocorticoids have a strong influence on breast cancer progression but their role in the first stages of breast cancer and, particularly, in myoepithelial cell regulation remains unclear. Consequently, we investigated the role of glucocorticoids in ductal carcinoma in situ (DCIS) in breast cancer, focusing specially on myoepithelial cells. To clarify ...... hiện toàn bộ
Analysis of terminal duct lobular unit involution in luminal A and basal breast cancersBreast Cancer Research - Tập 14 - Trang 1-8 - 2012
Xiaohong R Yang, Jonine D Figueroa, Roni T Falk, Hong Zhang, Ruth M Pfeiffer, Stephen M Hewitt, Jolanta Lissowska, Beata Peplonska, Louise Brinton, Montserrat Garcia-Closas, Mark E Sherman
Involution of terminal duct lobular units (TDLUs), the structures that give rise to most breast cancers, has been associated with reduced breast cancer risk. Data suggest that the etiology and pathogenesis of luminal A and core basal phenotype (CBP) breast cancers differ, but associations with TDLU involution are unknown. Accordingly, we performed a masked microscopic assessment of TDLU involution...... hiện toàn bộ