Breast Cancer Research

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Great, I've been let off the hook (the impact of advanced practice within the breast screening department)
Breast Cancer Research - Tập 4 - Trang 1-1 - 2002
C Lewis, MG Wallis
Patterns of cytokines and lymphocyte subsets in patients with breast and prostate cancer treated with a standardized mistletoe extract preparation
Breast Cancer Research - Tập 3 - Trang 1-1 - 2001
D Wetzel, A Gromöller, U Elsässer-Beile
Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis
Breast Cancer Research - Tập 20 - Trang 1-16 - 2018
Arantzazu Zubeldia-Plazaola, Leire Recalde-Percaz, Núria Moragas, Mireia Alcaraz, Xieng Chen, Mario Mancino, Patricia Fernández-Nogueira, Miquel Prats de Puig, Flavia Guzman, Aleix Noguera-Castells, Anna López-Plana, Estel Enreig, Neus Carbó, Vanessa Almendro, Pedro Gascón, Paloma Bragado, Gemma Fuster
The microenvironment and stress factors like glucocorticoids have a strong influence on breast cancer progression but their role in the first stages of breast cancer and, particularly, in myoepithelial cell regulation remains unclear. Consequently, we investigated the role of glucocorticoids in ductal carcinoma in situ (DCIS) in breast cancer, focusing specially on myoepithelial cells. To clarify ...... hiện toàn bộ
Are current drug development programmes realising the full potential of new agents? Introduction to Sessions 7 and 8
Breast Cancer Research - Tập 11 - Trang 1-2 - 2009
Stephen RD Johnston
Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics
Breast Cancer Research - Tập 12 - Trang 1-14 - 2010
Göran Jönsson, Johan Staaf, Johan Vallon-Christersson, Markus Ringnér, Karolina Holm, Cecilia Hegardt, Haukur Gunnarsson, Rainer Fagerholm, Carina Strand, Bjarni A Agnarsson, Outi Kilpivaara, Lena Luts, Päivi Heikkilä, Kristiina Aittomäki, Carl Blomqvist, Niklas Loman, Per Malmström, Håkan Olsson, Oskar Th Johannsson, Adalgeir Arason, Heli Nevanlinna, Rosa B Barkardottir, Åke Borg
Breast cancer is a profoundly heterogeneous disease with respect to biologic and clinical behavior. Gene-expression profiling has been used to dissect this complexity and to stratify tumors into intrinsic gene-expression subtypes, associated with distinct biology, patient outcome, and genomic alterations. Additionally, breast tumors occurring in individuals with germline BRCA1 or BRCA2 mutations t...... hiện toàn bộ
Recent breast cancer trends among Asian/Pacific Islander, Hispanic, and African-American women in the US: changes by tumor subtype
Breast Cancer Research - Tập 9 Số 6 - Trang 1-12 - 2007
Hausauer, Amelia K, Keegan, Theresa HM, Chang, Ellen T, Clarke, Christina A
Recently, unprecedented drops in breast cancer incidence have been reported for populations of mostly White European descent. Incidence patterns in non-White racial/ethnic groups are less described. Therefore, we examined population-based breast cancer incidence trends separately for US Asian/Pacific Islander, Hispanic, African-American, and non-Hispanic White women by etiologically relevant tumor...... hiện toàn bộ
Impact of full-field digital mammography on diagnostic work-up and surgical management of mammographic microcalcification
Breast Cancer Research - Tập 14 - Trang 1-14 - 2012
SM Bundred, J Zhou, S Whiteside, J Morris, NJ Bundred
Tumour-stromal interactions: Integrins and cell adhesions as modulators of mammary cell survival and transformation
Breast Cancer Research - Tập 3 - Trang 1-6 - 2001
Micah A Chrenek, Paul Wong, Valerie M Weaver
Stromal–epithelial interactions modulate mammary epithelial cell (MEC) growth and apoptosis by influencing cell adhesion and tissue organization. Perturbations in the mammary stroma and cell adhesion characterize breast tumors and underlie the altered tissue organization, disrupted tissue homeostasis and enhanced survival phenotype of the disease. Apoptosis resistance likely arises during malignan...... hiện toàn bộ
γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells
Breast Cancer Research - Tập 14 - Trang 1-15 - 2012
Céline Séveno, Delphine Loussouarn, Sophie Bréchet, Mario Campone, Philippe Juin, Sophie Barillé-Nion
Inappropriate Notch signaling, downstream of γ-secretase activity, is understood to have tumor-promoting function and to be associated with poor outcome in cancer, of the breast in particular. The molecular basis of antitumoral effects of its inhibitors, however, remains poorly characterized. Moreover, the effects of their combination with the pro-apoptotic pharmacologic inhibitor of Bcl-2/Bcl-xL,...... hiện toàn bộ
In utero estrogenic endocrine disruption alters the stroma to increase extracellular matrix density and mammary gland stiffness
Breast Cancer Research - Tập 22 - Trang 1-12 - 2020
Clarissa Wormsbaecher, Andrea R. Hindman, Alex Avendano, Marcos Cortes-Medina, Caitlin E. Jones, Andrew Bushman, Lotanna Onua, Claire E. Kovalchin, Alina R. Murphy, Hannah L. Helber, Ali Shapiro, Kyle Voytovitch, Xingyan Kuang, Renan Aguilar-Valenzuela, Jennifer L. Leight, Jonathan W. Song, Craig J. Burd
In utero endocrine disruption is linked to increased risk of breast cancer later in life. Despite numerous studies establishing this linkage, the long-term molecular changes that predispose mammary cells to carcinogenic transformation are unknown. Herein, we investigated how endocrine disrupting compounds (EDCs) drive changes within the stroma that can contribute to breast cancer susceptibility. W...... hiện toàn bộ
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