Biophysik
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Radiation protection of stimulated human lymphocytes by nicotinamide
Biophysik - Tập 22 - Trang 133-140 - 1983
Nicotinamide (NA) when added to human lymphocytes in vitro together with a mitogen, protected against the inhibition byγ and UV radiation of stimulated cell growth. When stimulated by phytohemagglutinin (PHA), concanavalin A (Con A) or pokeweed mitogen (PWM) maximum protection has been observed with ∼ 1 mM NA (dose reduction factor of 2–3). To obtain protection the cells had to be stimulated immed......
Cytotoxicity, genotoxicity and intracellular distribution of the Auger electron emitter 65Zn in two human cell lines
Biophysik - Tập 43 - Trang 15-22 - 2004
Cell survival, induction of apoptosis, and micronucleus formation have been examined in non-transformed human amnion fluid fibroblast-like (AFFL) cells and in a human squameous cell carcinoma (SCL-II) cell line after exposure to the Auger electron emitter 65Zn and after external low-LET radiation. Cellular uptake and subcellular distribution of 65Zn2+ were studied in vitro and the absorbed radiati......
Radiation sensitivity of N. pharaonis in comparison with E. coli K12 strains
Biophysik - Tập 41 - Trang 145-148 - 2014
To investigate the radiation sensitivity of the natronobacterium Natronomonas pharaonis in comparison with Escherichia coli strains (N. pharaonis DSM 2160T, E. coli strains AB1157 and K12λs) were exposed to gamma-radiation (60Co-γ-source, 100 Gy min–1) in the presence of oxygen (air) and under strongly reduced oxygen conditions (argon-saturated medium). After irradiation, the colony-forming abili......
Preliminary assessment of the risks associated with solar ultraviolet-A exposure
Biophysik - Tập 50 - Trang 219-229 - 2010
An approach is proposed to assess the periods of human skin exposure to solar ultraviolet-A (UV-A, 315–400 nm) irradiance in natural conditions that are able to yield doses found to trigger carcinogenesis in laboratory experiments. Weighting functions, adopted to perform such estimate are constructed, allowing for a comparison between environmental and laboratory doses. Furthermore, the impact of ......
Uncertainty analysis in internal dose calculations for cerium considering the uncertainties of biokinetic parameters and S values
Biophysik - Tập 59 - Trang 663-682 - 2020
Radioactive cerium and other lanthanides can be transported through the aquatic system into foodstuffs and then be incorporated by humans. Information on the uncertainty of reported dose coefficients for exposed members of the public is then needed for risk analysis. In this study, uncertainties of dose coefficients due to the ingestion of the radionuclides 141Ce and 144Ce were estimated. Accordin......
Effects of antibiotics on UV-stimulated tube growth ofPinus silvestris pollen
Biophysik - Tập 14 - Trang 323-328 - 1977
Studies were made to investigate the effects of different antibiotics on unirradiated pollen and on pollen with enhanced tube growth, stimulated by low doses of UV-light. The antibiotics mitomycin, chloramphenicol, tetracyclin, penicillin, nystatin and carbony-cyanid phenylhydrazon were not able to suppress tube growth stimulation of pine pollen. The data obtained are discussed in view of the stim......
Response to the comment on “Studies of radon-exposed miner cohorts using a biologically based model: comparison of current Czech and French data with historic data from China and Colorado” by W.F. Heidenreich, L. Tomášek, A. Rogel, D. Laurier, M. Tirmarche (2004) Radiat Environ Biophys 43:247–256
Biophysik - Tập 44 - Trang 153-154 - 2005
The effectiveness of the high-LET radiations from the boron neutron capture [10B(n,α)7Li] reaction determined for induction of chromosome aberrations and apoptosis in lymphocytes of human blood samples
Biophysik - Tập 54 - Trang 91-102 - 2014
Provided that a selective accumulation of 10B-containing compounds is introduced in tumor cells, following irradiation by thermal neutrons produces high-LET alpha-particles (4He) and recoiling lithium-7 (7Li) nuclei emitted during the capture of thermalized neutrons (0.025 eV) from 10B. To estimate the biological effectiveness of this boron neutron capture [10B(n,α)7Li] reaction, the chromosome ab......
A new EPR dosimeter based on glutamic acid for radiation processing application
Biophysik - Tập 58 - Trang 501-511 - 2019
l-Glutamic acid (L-GA) pellets (3.8 mm × 4 mm) and powder dosimeters were studied in the dose range of 0.1–150 kGy using the electron paramagnetic resonance (EPR) technique. The EPR spectra of irradiated L-GA pellets showed an EPR signal with eight lines, and the intensity of the signal increased with an increase of absorbed dose. The results obtained in terms of the energy-absorption coefficients......
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