Biomarker Research
SCIE-ISI SCOPUS (2013-2025)
2050-7771
Cơ quản chủ quản: BioMed Central Ltd. , BMC
Lĩnh vực:
Clinical BiochemistryBiochemistry (medical)Molecular Medicine
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases
Tập 2 Số 1 - 2014
Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application
Tập 1 Số 1 - 2013
AbstractJAK-STAT (Janus associated kinase-signal transducer and activator of
transcription) pathway plays a critical role in transduction of extracellular
signals from cytokines and growth factors involved in hematopoiesis, immune
regulation, fertility, lactation, growth and embryogenesis. JAK family contains
four cytoplasmic tyrosine kinases, JAK1-3 and Tyk2. Seven STAT proteins have
been identif...
Nanobody-based CAR-T cells for cancer immunotherapy
Tập 10 Số 1 - 2022
AbstractChimeric antigen receptor T-cell (CAR-T) therapy is the result of
combining genetic engineering-based cancer immunotherapy with adoptive cell
therapy (ACT). CAR-T therapy has been successful in treating various types of
hematological cancers. CARs are receptors made of an extracellular domain, a
membrane-spanning domain, and an intracellular domain. The extracellular domain
of CARs harbors...
Biomarkers for hepatocellular carcinoma: progression in early diagnosis, prognosis, and personalized therapy
- 2013
Abstract Hepatocellular carcinoma (HCC) is one of the most common malignant
tumors in the world. Currently, surgical resection, liver transplantation, and
local ablation are considered curative therapeutic practices for HCC. The
diagnosis of HCC without pathologic confirmation is achieved by analyzing serum
alpha-fetoprotein (AFP) levels combined with imaging techniques, including
ultrasonography,...
Metabolomic analyses for atherosclerosis, diabetes, and obesity
Tập 1 Số 1 - 2013
Abstract Insulin resistance associated with type 2 diabetes mellitus (T2DM),
obesity, and atherosclerosis is a global health problem. A portfolio of
abnormalities of metabolic and vascular homeostasis accompanies T2DM and
obesity, which are believed to conspire to lead to accelerated atherosclerosis
and premature death. The complexity of metabolic changes in the diseases
presents challenges for a ...
Organ specific responses to first-line lenvatinib plus anti-PD-1 antibodies in patients with unresectable hepatocellular carcinoma: a retrospective analysis
Tập 9 Số 1 - 2021
Abstract Background We evaluated organ-specific response rates (OSRRs) to
first-line lenvatinib plus anti-PD-1 antibodies in patients with advanced
hepatocellular carcinoma (HCC). Methods This retrospective analysis included
Chinese patients with unresectable/advanced HCC who received first-line
lenvatinib (8 mg/day) plus ≥3 infusions of anti-PD-1 antibodies between October
2018 and May 2020. Tumo...